| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.102301 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0907651 |
| GOLGA4 | golgin A4 | 0.0714167 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0644697 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.053484 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0484175 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0467025 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0414202 |
| OGA | O-GlcNAcase | 0.0400408 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0387138 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0378847 |
| ZNF292 | zinc finger protein 292 | 0.0373674 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0370522 |
| RPL21 | ribosomal protein L21 | 0.0358372 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0353471 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0348543 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0323111 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0311518 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0305805 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0293934 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0293637 |
| RNF145 | ring finger protein 145 | 0.0291595 |
| JMJD1C | jumonji domain containing 1C | 0.0291574 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0287562 |
| SBF2 | SET binding factor 2 | 0.028238 |
| SUCO | SUN domain containing ossification factor | 0.0278662 |
| USP3 | ubiquitin specific peptidase 3 | 0.0278052 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0275155 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0272876 |
| FAM135A | family with sequence similarity 135, member A | 0.0271008 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0269552 |
| NUP58 | nucleoporin 58 | 0.0268289 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.026793 |
| FTL | ferritin, light polypeptide | 0.0267456 |
| COG5 | component of oligomeric golgi complex 5 | 0.0265946 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0262517 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0259634 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.02591 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.025808 |
| RBM39 | RNA binding motif protein 39 | 0.0254913 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0252039 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0251597 |
| RPS2 | ribosomal protein S2 | 0.0250134 |
| CALU | calumenin | 0.0244954 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0238584 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0234293 |
| TMEM41B | transmembrane protein 41B | 0.0233614 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.023304 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0232527 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0230913 |
| RLF | rearranged L-myc fusion | 0.0230095 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.023007 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0228418 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0227941 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0223423 |
| PUM2 | pumilio RNA-binding family member 2 | 0.022086 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0219113 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0218936 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0218392 |
| HELZ | helicase with zinc finger | 0.0217243 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0217103 |
| PTEN | phosphatase and tensin homolog | 0.0216316 |
| NCKAP1 | NCK-associated protein 1 | 0.0215943 |
| MATR3 | matrin 3 | 0.0214651 |
| SLMAP | sarcolemma associated protein | 0.0212664 |
| CANX | calnexin | 0.0211672 |
| PDS5B | PDS5 cohesin associated factor B | 0.0211163 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0210377 |
| CCDC186 | coiled-coil domain containing 186 | 0.0206525 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0203321 |
| FAM13A | family with sequence similarity 13, member A | 0.0202004 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0201743 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0200837 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0200381 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0198481 |
| PREPL | prolyl endopeptidase-like | 0.0198336 |
| ZFR | zinc finger RNA binding protein | 0.0196499 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0196331 |
| XPO1 | exportin 1 | 0.0196261 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0195973 |
| KIF5B | kinesin family member 5B | 0.0195967 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0195674 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.019488 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.0192953 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.019166 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0191184 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0190323 |
| TLK1 | tousled-like kinase 1 | 0.0190087 |
| NEK7 | NIMA-related kinase 7 | 0.0189292 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0189112 |
| WDR26 | WD repeat domain 26 | 0.0189086 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0188481 |
| TOP1 | topoisomerase (DNA) I | 0.0186948 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0186472 |
| TPR | translocated promoter region, nuclear basket protein | 0.0186354 |
| HYOU1 | hypoxia up-regulated 1 | 0.018578 |
| UBE3A | ubiquitin protein ligase E3A | 0.01822 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.018161 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0181585 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0181477 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | -0.195812 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.133648 |
| KRT20 | keratin 20, type I | -0.13168 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.13013 |
| LAMA4 | laminin, alpha 4 | -0.105809 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0960786 |
| SLC45A4 | solute carrier family 45, member 4 | -0.092723 |
| SMAD3 | SMAD family member 3 | -0.0917174 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0868432 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0850772 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0845137 |
| TJP1 | tight junction protein 1 | -0.0837112 |
| EGR1 | early growth response 1 | -0.0831523 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0815929 |
| LMO7 | LIM domain 7 | -0.0813008 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0803405 |
| INTS6 | integrator complex subunit 6 | -0.0786431 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0782433 |
| KRT8 | keratin 8, type II | -0.0770293 |
| ANXA2 | annexin A2 | -0.0727794 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0710278 |
| TRIB1 | tribbles pseudokinase 1 | -0.0695918 |
| ACTN4 | actinin, alpha 4 | -0.0683871 |
| MYO1E | myosin IE | -0.0645288 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0613727 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0601093 |
| POF1B | premature ovarian failure, 1B | -0.0578826 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0575525 |
| FRY | furry homolog (Drosophila) | -0.0567327 |
| RNF213 | ring finger protein 213 | -0.0556828 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0556075 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0555824 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0550483 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0549757 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0531106 |
| DIAPH2 | diaphanous-related formin 2 | -0.0529422 |
| CTBP2 | C-terminal binding protein 2 | -0.0518788 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0516655 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0513985 |
| PRR5L | proline rich 5 like | -0.0497974 |
| TMEM65 | transmembrane protein 65 | -0.048959 |
| KRT19 | keratin 19, type I | -0.0486476 |
| AHNAK | AHNAK nucleoprotein | -0.0480291 |
| ACTG1 | actin gamma 1 | -0.0479512 |
| TMSB10 | thymosin beta 10 | -0.0478219 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0474341 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0473254 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0466758 |
| JUN | jun proto-oncogene | -0.0464509 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0456731 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0454637 |
| KRT18 | keratin 18, type I | -0.0452851 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0435521 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0430255 |
| POTEF | POTE ankyrin domain family, member F | -0.0426558 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.042426 |
| VCL | vinculin | -0.042408 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0414837 |
| NTN4 | netrin 4 | -0.0412145 |
| PKM | pyruvate kinase, muscle | -0.0406012 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0405815 |
| SLC38A2 | solute carrier family 38, member 2 | -0.040396 |
| GSN | gelsolin | -0.0398346 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0394304 |
| ETV6 | ets variant 6 | -0.0393691 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0392134 |
| MCL1 | myeloid cell leukemia 1 | -0.0384456 |
| EZR | ezrin | -0.0379716 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0375671 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0373577 |
| DGKH | diacylglycerol kinase, eta | -0.0363502 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0362974 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0362558 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0354602 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0353668 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0353353 |
| MMP7 | matrix metallopeptidase 7 | -0.0353238 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0352619 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0351043 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0343467 |
| SGMS2 | sphingomyelin synthase 2 | -0.0340986 |
| CAPN8 | calpain 8 | -0.0340232 |
| LYZ | lysozyme | -0.033695 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0336205 |
| NDRG1 | N-myc downstream regulated 1 | -0.0332381 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0331329 |
| ASPH | aspartate beta-hydroxylase | -0.0321558 |
| TMEM123 | transmembrane protein 123 | -0.0321437 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0321408 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.03153 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0314001 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0313115 |
| FAT1 | FAT atypical cadherin 1 | -0.0309563 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0304464 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0302446 |
| FHL2 | four and a half LIM domains 2 | -0.0300585 |
| S100A10 | S100 calcium binding protein A10 | -0.0300505 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0296985 |
| MYO5B | myosin VB | -0.029536 |
| PLK2 | polo-like kinase 2 | -0.0292382 |
