Procainamide (hydrochloride)_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Procainamide (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Procainamide (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
CLU clusterin 0.143829
MTSS1 metastasis suppressor 1 0.132376
FLNB filamin B, beta 0.0931068
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.082524
RPS12 ribosomal protein S12 0.0811551
RPL21 ribosomal protein L21 0.0805706
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0777971
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.0754791
RPS2 ribosomal protein S2 0.0722953
RPS6 ribosomal protein S6 0.0697273
RPS3 ribosomal protein S3 0.069011
ALCAM activated leukocyte cell adhesion molecule 0.0689897
MSN moesin 0.0675504
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0666
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.063666
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0631978
RPS8 ribosomal protein S8 0.0595302
MEF2A myocyte enhancer factor 2A 0.0555864
RAI14 retinoic acid induced 14 0.0546812
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0478977
PRRC2C proline-rich coiled-coil 2C 0.0465824
RIN2 Ras and Rab interactor 2 0.0442362
SLC35F3 solute carrier family 35, member F3 0.0435523
TPT1 tumor protein, translationally-controlled 1 0.0421945
FOSL1 FOS-like antigen 1 0.0411429
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0410127
SQSTM1 sequestosome 1 0.0406594
KTN1 kinectin 1 (kinesin receptor) 0.0402964
RPLP2 ribosomal protein, large, P2 0.0400244
BZW1 basic leucine zipper and W2 domains 1 0.038218
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0378644
NAV2 neuron navigator 2 0.0369911
TIMP3 TIMP metallopeptidase inhibitor 3 0.0366204
THOC2 THO complex 2 0.0359331
DOCK5 dedicator of cytokinesis 5 0.0355043
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0351521
ENO1 enolase 1, (alpha) 0.0351082
SET SET nuclear proto-oncogene 0.0339547
MACF1 microtubule-actin crosslinking factor 1 0.0337781
LAMC2 laminin, gamma 2 0.0336177
PDGFB platelet-derived growth factor beta polypeptide 0.0335487
S100A2 S100 calcium binding protein A2 0.0323648
RSL1D1 ribosomal L1 domain containing 1 0.031617
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.031549
CAPRIN2 caprin family member 2 0.0313999
RPS29 ribosomal protein S29 0.0313875
SBF2 SET binding factor 2 0.0313701
BCAR3 breast cancer anti-estrogen resistance 3 0.0306089
CAPN2 calpain 2, (m/II) large subunit 0.0300298
RPL37A ribosomal protein L37a 0.0299913
NAP1L1 nucleosome assembly protein 1-like 1 0.0298926
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0295139
ANLN anillin, actin binding protein 0.0293753
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.0293601
TPX2 TPX2, microtubule-associated 0.0292108
RPS7 ribosomal protein S7 0.0290426
DSTN destrin (actin depolymerizing factor) 0.0290155
RPL12 ribosomal protein L12 0.0288327
CNRIP1 cannabinoid receptor interacting protein 1 0.028466
ANXA5 annexin A5 0.0284319
AKAP13 A kinase (PRKA) anchor protein 13 0.0279731
CSTB cystatin B (stefin B) 0.0279705
NACA nascent polypeptide-associated complex alpha subunit 0.0278904
KIAA1217 KIAA1217 0.0274698
RPL7A ribosomal protein L7a 0.0274571
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0273956
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0273916
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0271276
SRRM1 serine/arginine repetitive matrix 1 0.0267095
RPL30 ribosomal protein L30 0.0266189
SPATS2 spermatogenesis associated, serine-rich 2 0.0265965
RPS27 ribosomal protein S27 0.0264961
RNF217 ring finger protein 217 0.0264621
MKI67 marker of proliferation Ki-67 0.026392
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 0.0259482
TMEM165 transmembrane protein 165 0.0258602
TMF1 TATA element modulatory factor 1 0.0255177
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0253609
RPL23 ribosomal protein L23 0.0252069
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0246769
PRKRIP1 PRKR interacting protein 1 (IL11 inducible) 0.0246288
SLMAP sarcolemma associated protein 0.0245834
TM4SF1 transmembrane 4 L six family member 1 0.0244634
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0239789
SMYD3 SET and MYND domain containing 3 0.0239638
VCL vinculin 0.0239577
RTN4 reticulon 4 0.0237518
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0236158
SLTM SAFB-like, transcription modulator 0.0235276
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.0234282
ITCH itchy E3 ubiquitin protein ligase 0.0233507
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0232623
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0232424
CDKN2A cyclin-dependent kinase inhibitor 2A 0.0232072
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0229043
XRN1 5'-3' exoribonuclease 1 0.0228925
TPM3 tropomyosin 3 0.0228724
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.022864
VMP1 vacuole membrane protein 1 0.0227523
RPL26 ribosomal protein L26 0.0227435

decreased expression

Symbol Name Standardized Value
NDRG1 N-myc downstream regulated 1 -0.202807
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.166087
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.139117
LOC112694756 uncharaterized LOC112694756 -0.124853
TGM2 transglutaminase 2 -0.0876115
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0836381
IGF2 insulin-like growth factor 2 -0.0736751
FTH1 ferritin, heavy polypeptide 1 -0.0736438
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0725594
PKM pyruvate kinase, muscle -0.0690938
LDHA lactate dehydrogenase A -0.0673855
POTEF POTE ankyrin domain family, member F -0.0661542
TMSB10 thymosin beta 10 -0.065833
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.05951
ACTN4 actinin, alpha 4 -0.0588345
ANXA1 annexin A1 -0.0579248
HSPG2 heparan sulfate proteoglycan 2 -0.055001
S100A10 S100 calcium binding protein A10 -0.0521938
H1-0 H1.0 linker histone -0.0507641
MYOF myoferlin -0.0487412
CYB5R3 cytochrome b5 reductase 3 -0.0476708
PODXL podocalyxin-like -0.0470257
MBNL2 muscleblind-like splicing regulator 2 -0.0466351
SULF1 sulfatase 1 -0.0453484
BSG basigin (Ok blood group) -0.0445873
COPA coatomer protein complex, subunit alpha -0.0436961
TMSB4X thymosin beta 4, X-linked -0.0435363
CD44 CD44 molecule (Indian blood group) -0.0423601
EEF2 eukaryotic translation elongation factor 2 -0.0413358
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0405087
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.040042
MORF4L2 mortality factor 4 like 2 -0.0397558
LAMA5 laminin, alpha 5 -0.0391926
SLC38A2 solute carrier family 38, member 2 -0.0390386
LMAN1 lectin, mannose-binding, 1 -0.0385889
KRT17 keratin 17, type I -0.0382231
IFITM3 interferon induced transmembrane protein 3 -0.0377799
TINAGL1 tubulointerstitial nephritis antigen-like 1 -0.0376045
SFTPA2 surfactant protein A2 -0.0364312
SULF2 sulfatase 2 -0.0362147
MT1X metallothionein 1X -0.035995
YBX1 Y box binding protein 1 -0.0352917
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.034706
FTL ferritin, light polypeptide -0.0342637
ARF1 ADP-ribosylation factor 1 -0.033954
UBC ubiquitin C -0.0337178
FLNA filamin A, alpha -0.0321887
SERINC3 serine incorporator 3 -0.0318612
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0315428
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0314563
INTS6 integrator complex subunit 6 -0.031386
IFITM1 interferon induced transmembrane protein 1 -0.0308398
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0303566
PLEC plectin -0.0297974
PCDH1 protocadherin 1 -0.029146
PFN1 profilin 1 -0.0290733
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -0.0289471
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0289133
ANKRD28 ankyrin repeat domain 28 -0.028882
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0286769
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.028529
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0283177
RPLP1 ribosomal protein, large, P1 -0.0280837
HOOK2 hook microtubule-tethering protein 2 -0.0280478
FNDC3B fibronectin type III domain containing 3B -0.0279614
EPHA2 EPH receptor A2 -0.0279247
ANXA2 annexin A2 -0.0276674
EZR ezrin -0.0276546
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -0.0267852
ATP5F1B ATP synthase F1 subunit beta -0.0262708
CAV1 caveolin 1, caveolae protein, 22kDa -0.0257993
NFIB nuclear factor I/B -0.0257209
TXNRD1 thioredoxin reductase 1 -0.0256631
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0254547
MRPS6 mitochondrial ribosomal protein S6 -0.0254083
ITGB4 integrin, beta 4 -0.025373
ZNFX1 zinc finger, NFX1-type containing 1 -0.0253105
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.0252718
PLTP phospholipid transfer protein -0.0250998
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.0250452
TMEM123 transmembrane protein 123 -0.0248576
RAP1B RAP1B, member of RAS oncogene family -0.0245283
COG6 component of oligomeric golgi complex 6 -0.0245217
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0243856
TAGLN2 transgelin 2 -0.0243546
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.0239382
CMIP c-Maf inducing protein -0.0235347
RPL35A ribosomal protein L35a -0.0234812
CBX3 chromobox homolog 3 -0.0232662
LMO7 LIM domain 7 -0.0232409
JMJD1C jumonji domain containing 1C -0.0231509
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 -0.022919
CEMIP cell migration inducing protein, hyaluronan binding -0.0227737
CTSD cathepsin D -0.0226739
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0226239
VDAC1 voltage-dependent anion channel 1 -0.0225933
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 -0.0225395
FOXP1 forkhead box P1 -0.022115
UBE2H ubiquitin-conjugating enzyme E2H -0.0220179
SCARB2 scavenger receptor class B, member 2 -0.0219912