| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | 0.143829 |
| MTSS1 | metastasis suppressor 1 | 0.132376 |
| FLNB | filamin B, beta | 0.0931068 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.082524 |
| RPS12 | ribosomal protein S12 | 0.0811551 |
| RPL21 | ribosomal protein L21 | 0.0805706 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0777971 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0754791 |
| RPS2 | ribosomal protein S2 | 0.0722953 |
| RPS6 | ribosomal protein S6 | 0.0697273 |
| RPS3 | ribosomal protein S3 | 0.069011 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0689897 |
| MSN | moesin | 0.0675504 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0666 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.063666 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0631978 |
| RPS8 | ribosomal protein S8 | 0.0595302 |
| MEF2A | myocyte enhancer factor 2A | 0.0555864 |
| RAI14 | retinoic acid induced 14 | 0.0546812 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0478977 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0465824 |
| RIN2 | Ras and Rab interactor 2 | 0.0442362 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0435523 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0421945 |
| FOSL1 | FOS-like antigen 1 | 0.0411429 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0410127 |
| SQSTM1 | sequestosome 1 | 0.0406594 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0402964 |
| RPLP2 | ribosomal protein, large, P2 | 0.0400244 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.038218 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0378644 |
| NAV2 | neuron navigator 2 | 0.0369911 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0366204 |
| THOC2 | THO complex 2 | 0.0359331 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0355043 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0351521 |
| ENO1 | enolase 1, (alpha) | 0.0351082 |
| SET | SET nuclear proto-oncogene | 0.0339547 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0337781 |
| LAMC2 | laminin, gamma 2 | 0.0336177 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0335487 |
| S100A2 | S100 calcium binding protein A2 | 0.0323648 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.031617 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.031549 |
| CAPRIN2 | caprin family member 2 | 0.0313999 |
| RPS29 | ribosomal protein S29 | 0.0313875 |
| SBF2 | SET binding factor 2 | 0.0313701 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0306089 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0300298 |
| RPL37A | ribosomal protein L37a | 0.0299913 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0298926 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0295139 |
| ANLN | anillin, actin binding protein | 0.0293753 |
| NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 0.0293601 |
| TPX2 | TPX2, microtubule-associated | 0.0292108 |
| RPS7 | ribosomal protein S7 | 0.0290426 |
| DSTN | destrin (actin depolymerizing factor) | 0.0290155 |
| RPL12 | ribosomal protein L12 | 0.0288327 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.028466 |
| ANXA5 | annexin A5 | 0.0284319 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0279731 |
| CSTB | cystatin B (stefin B) | 0.0279705 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0278904 |
| KIAA1217 | KIAA1217 | 0.0274698 |
| RPL7A | ribosomal protein L7a | 0.0274571 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0273956 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0273916 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0271276 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0267095 |
| RPL30 | ribosomal protein L30 | 0.0266189 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0265965 |
| RPS27 | ribosomal protein S27 | 0.0264961 |
| RNF217 | ring finger protein 217 | 0.0264621 |
| MKI67 | marker of proliferation Ki-67 | 0.026392 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0259482 |
| TMEM165 | transmembrane protein 165 | 0.0258602 |
| TMF1 | TATA element modulatory factor 1 | 0.0255177 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0253609 |
| RPL23 | ribosomal protein L23 | 0.0252069 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0246769 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0246288 |
| SLMAP | sarcolemma associated protein | 0.0245834 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0244634 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0239789 |
| SMYD3 | SET and MYND domain containing 3 | 0.0239638 |
| VCL | vinculin | 0.0239577 |
| RTN4 | reticulon 4 | 0.0237518 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0236158 |
| SLTM | SAFB-like, transcription modulator | 0.0235276 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0234282 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0233507 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0232623 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0232424 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0232072 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0229043 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0228925 |
| TPM3 | tropomyosin 3 | 0.0228724 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.022864 |
| VMP1 | vacuole membrane protein 1 | 0.0227523 |
| RPL26 | ribosomal protein L26 | 0.0227435 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.202807 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166087 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.139117 |
| LOC112694756 | uncharaterized LOC112694756 | -0.124853 |
| TGM2 | transglutaminase 2 | -0.0876115 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0836381 |
| IGF2 | insulin-like growth factor 2 | -0.0736751 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0736438 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0725594 |
| PKM | pyruvate kinase, muscle | -0.0690938 |
| LDHA | lactate dehydrogenase A | -0.0673855 |
| POTEF | POTE ankyrin domain family, member F | -0.0661542 |
| TMSB10 | thymosin beta 10 | -0.065833 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.05951 |
| ACTN4 | actinin, alpha 4 | -0.0588345 |
| ANXA1 | annexin A1 | -0.0579248 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.055001 |
| S100A10 | S100 calcium binding protein A10 | -0.0521938 |
| H1-0 | H1.0 linker histone | -0.0507641 |
| MYOF | myoferlin | -0.0487412 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0476708 |
| PODXL | podocalyxin-like | -0.0470257 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0466351 |
| SULF1 | sulfatase 1 | -0.0453484 |
| BSG | basigin (Ok blood group) | -0.0445873 |
| COPA | coatomer protein complex, subunit alpha | -0.0436961 |
| TMSB4X | thymosin beta 4, X-linked | -0.0435363 |
| CD44 | CD44 molecule (Indian blood group) | -0.0423601 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0413358 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0405087 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.040042 |
| MORF4L2 | mortality factor 4 like 2 | -0.0397558 |
| LAMA5 | laminin, alpha 5 | -0.0391926 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0390386 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0385889 |
| KRT17 | keratin 17, type I | -0.0382231 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0377799 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0376045 |
| SFTPA2 | surfactant protein A2 | -0.0364312 |
| SULF2 | sulfatase 2 | -0.0362147 |
| MT1X | metallothionein 1X | -0.035995 |
| YBX1 | Y box binding protein 1 | -0.0352917 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.034706 |
| FTL | ferritin, light polypeptide | -0.0342637 |
| ARF1 | ADP-ribosylation factor 1 | -0.033954 |
| UBC | ubiquitin C | -0.0337178 |
| FLNA | filamin A, alpha | -0.0321887 |
| SERINC3 | serine incorporator 3 | -0.0318612 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0315428 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0314563 |
| INTS6 | integrator complex subunit 6 | -0.031386 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0308398 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0303566 |
| PLEC | plectin | -0.0297974 |
| PCDH1 | protocadherin 1 | -0.029146 |
| PFN1 | profilin 1 | -0.0290733 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0289471 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0289133 |
| ANKRD28 | ankyrin repeat domain 28 | -0.028882 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | -0.0286769 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.028529 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0283177 |
| RPLP1 | ribosomal protein, large, P1 | -0.0280837 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0280478 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0279614 |
| EPHA2 | EPH receptor A2 | -0.0279247 |
| ANXA2 | annexin A2 | -0.0276674 |
| EZR | ezrin | -0.0276546 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | -0.0267852 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0262708 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0257993 |
| NFIB | nuclear factor I/B | -0.0257209 |
| TXNRD1 | thioredoxin reductase 1 | -0.0256631 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0254547 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0254083 |
| ITGB4 | integrin, beta 4 | -0.025373 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0253105 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0252718 |
| PLTP | phospholipid transfer protein | -0.0250998 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0250452 |
| TMEM123 | transmembrane protein 123 | -0.0248576 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0245283 |
| COG6 | component of oligomeric golgi complex 6 | -0.0245217 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0243856 |
| TAGLN2 | transgelin 2 | -0.0243546 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0239382 |
| CMIP | c-Maf inducing protein | -0.0235347 |
| RPL35A | ribosomal protein L35a | -0.0234812 |
| CBX3 | chromobox homolog 3 | -0.0232662 |
| LMO7 | LIM domain 7 | -0.0232409 |
| JMJD1C | jumonji domain containing 1C | -0.0231509 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.022919 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0227737 |
| CTSD | cathepsin D | -0.0226739 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0226239 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0225933 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0225395 |
| FOXP1 | forkhead box P1 | -0.022115 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0220179 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0219912 |