| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.104934 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0696541 |
| WDR43 | WD repeat domain 43 | 0.0671408 |
| NUP58 | nucleoporin 58 | 0.0638381 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.063529 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0601958 |
| ZNF292 | zinc finger protein 292 | 0.0525855 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.052358 |
| MED13L | mediator complex subunit 13-like | 0.0495314 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0474013 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0470028 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0469711 |
| USP15 | ubiquitin specific peptidase 15 | 0.0468561 |
| RTN4 | reticulon 4 | 0.0458664 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0457305 |
| RPS2 | ribosomal protein S2 | 0.0454112 |
| ATP13A3 | ATPase type 13A3 | 0.0449804 |
| RPL21 | ribosomal protein L21 | 0.0426688 |
| NCKAP1 | NCK-associated protein 1 | 0.0422964 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0417884 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0415609 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0400423 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0398684 |
| BRD2 | bromodomain containing 2 | 0.0398546 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0397817 |
| SPAG9 | sperm associated antigen 9 | 0.0384502 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0383325 |
| NUP153 | nucleoporin 153kDa | 0.0383222 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0382505 |
| APP | amyloid beta (A4) precursor protein | 0.0380006 |
| WDR26 | WD repeat domain 26 | 0.0376366 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0374231 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0369854 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0367147 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0364214 |
| RNF145 | ring finger protein 145 | 0.0360463 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.035874 |
| RPS12 | ribosomal protein S12 | 0.035864 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0357837 |
| QKI | QKI, KH domain containing, RNA binding | 0.0356874 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0355912 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0345938 |
| RPL37A | ribosomal protein L37a | 0.0345197 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0344618 |
| RLF | rearranged L-myc fusion | 0.0342287 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0342178 |
| KIF5B | kinesin family member 5B | 0.0339291 |
| RASA2 | RAS p21 protein activator 2 | 0.0335284 |
| CUL3 | cullin 3 | 0.0333684 |
| TFG | TRK-fused gene | 0.0330784 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0328828 |
| OLA1 | Obg-like ATPase 1 | 0.0328069 |
| RBM39 | RNA binding motif protein 39 | 0.0325122 |
| NEK7 | NIMA-related kinase 7 | 0.0324861 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0318979 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0318235 |
| TNPO1 | transportin 1 | 0.031613 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.030311 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0297366 |
| RBM33 | RNA binding motif protein 33 | 0.0296959 |
| ABI1 | abl-interactor 1 | 0.0296895 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0296332 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0294881 |
| SETD5 | SET domain containing 5 | 0.0293289 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0291038 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0290914 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0290827 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0290327 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0288593 |
| CCNL1 | cyclin L1 | 0.0286834 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0286786 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.028467 |
| FOXJ3 | forkhead box J3 | 0.028348 |
| MSN | moesin | 0.0283227 |
| VCL | vinculin | 0.0282601 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.028072 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0280282 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0278869 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0272494 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0271955 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0271234 |
| CRY1 | cryptochrome circadian clock 1 | 0.0270019 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0267036 |
| TFRC | transferrin receptor | 0.026648 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.026625 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0265971 |
| MEF2A | myocyte enhancer factor 2A | 0.0265371 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.026144 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0258342 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.025787 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0257404 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0256486 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0256333 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0255592 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0254247 |
| TEX10 | testis expressed 10 | 0.0254101 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.025311 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0250633 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0250498 |
| RPL23 | ribosomal protein L23 | 0.0250135 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.284807 |
| EFNA5 | ephrin-A5 | -0.162984 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.123661 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.122193 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.113797 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.107637 |
| TMSB10 | thymosin beta 10 | -0.101245 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.100475 |
| CDH13 | cadherin 13 | -0.0877195 |
| EGR1 | early growth response 1 | -0.0864588 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0782491 |
| NDRG1 | N-myc downstream regulated 1 | -0.0694657 |
| LSAMP | limbic system-associated membrane protein | -0.0649142 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0620687 |
| DTNA | dystrobrevin, alpha | -0.0616005 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0615734 |
| KIAA1549L | KIAA1549-like | -0.0609431 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0600896 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0600661 |
| NAV1 | neuron navigator 1 | -0.0600535 |
| EXT1 | exostosin glycosyltransferase 1 | -0.05628 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0560687 |
| MMP12 | matrix metallopeptidase 12 | -0.0560328 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0554104 |
| RUNX1 | runt-related transcription factor 1 | -0.0551009 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0547331 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0536499 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0533899 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0515072 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0514333 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0494113 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0481355 |
| JUN | jun proto-oncogene | -0.0474098 |
| MYO10 | myosin X | -0.0466921 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0443562 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0427086 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.041804 |
| FN1 | fibronectin 1 | -0.0404904 |
| NTM | neurotrimin | -0.0402645 |
| KIAA1217 | KIAA1217 | -0.0401052 |
| RNF213 | ring finger protein 213 | -0.038353 |
| RIGI | RNA sensor RIG-I | -0.0375256 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.036172 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0360914 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0359496 |
| PTK2 | protein tyrosine kinase 2 | -0.0358077 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.035611 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0353378 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0352797 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0344382 |
| PRKCE | protein kinase C, epsilon | -0.0335541 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0333008 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0332139 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0323257 |
| GPC6 | glypican 6 | -0.0320701 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0318335 |
| KDM2B | lysine (K)-specific demethylase 2B | -0.0305407 |
| FMNL2 | formin-like 2 | -0.0300727 |
| MCL1 | myeloid cell leukemia 1 | -0.0299069 |
| HMGA2 | high mobility group AT-hook 2 | -0.0297647 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0293999 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0292021 |
| FOXP1 | forkhead box P1 | -0.0291271 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0277083 |
| RPLP1 | ribosomal protein, large, P1 | -0.0273528 |
| CAVIN1 | caveolae associated protein 1 | -0.0270104 |
| TPM4 | tropomyosin 4 | -0.026854 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0264373 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0263482 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0261836 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0256722 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0255768 |
| DGKH | diacylglycerol kinase, eta | -0.0251072 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0249903 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0247028 |
| TENM2 | teneurin transmembrane protein 2 | -0.0246981 |
| MYO9A | myosin IXA | -0.0245392 |
| RPL35A | ribosomal protein L35a | -0.0242383 |
| ASPH | aspartate beta-hydroxylase | -0.0241113 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0238731 |
| SSH2 | slingshot protein phosphatase 2 | -0.0233902 |
| TAOK1 | TAO kinase 1 | -0.0230887 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.023081 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0229602 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0229327 |
| HAS2 | hyaluronan synthase 2 | -0.0228469 |
| CD109 | CD109 molecule | -0.022705 |
| MAP4 | microtubule-associated protein 4 | -0.0225757 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.022227 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0221698 |
| DST | dystonin | -0.0219099 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0218519 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0217415 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0213756 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0213561 |
| CDK6 | cyclin-dependent kinase 6 | -0.0212638 |
| RAD51B | RAD51 paralog B | -0.0212178 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0209273 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0208831 |
| SBF2 | SET binding factor 2 | -0.0208128 |
