| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.116094 |
| TXNIP | thioredoxin interacting protein | 0.115811 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0964225 |
| FAM13A | family with sequence similarity 13, member A | 0.0862502 |
| RNF145 | ring finger protein 145 | 0.0749926 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0709041 |
| NDRG1 | N-myc downstream regulated 1 | 0.0703226 |
| EZR | ezrin | 0.0657338 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0601041 |
| ZNF292 | zinc finger protein 292 | 0.0596327 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.056343 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0549838 |
| RBM39 | RNA binding motif protein 39 | 0.0540224 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0538655 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0533253 |
| MED13L | mediator complex subunit 13-like | 0.0530334 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0523428 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0519171 |
| EREG | epiregulin | 0.0495173 |
| SETD5 | SET domain containing 5 | 0.0478884 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0466723 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0459948 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0454815 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0438948 |
| NUP58 | nucleoporin 58 | 0.0435618 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0434617 |
| GOLGA4 | golgin A4 | 0.0431044 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0413391 |
| ANXA1 | annexin A1 | 0.03976 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0392419 |
| PCBP2 | poly(rC) binding protein 2 | 0.0388999 |
| USP3 | ubiquitin specific peptidase 3 | 0.0381717 |
| RPS2 | ribosomal protein S2 | 0.0377064 |
| VEGFA | vascular endothelial growth factor A | 0.0376815 |
| VMP1 | vacuole membrane protein 1 | 0.0370457 |
| RPS6 | ribosomal protein S6 | 0.0368034 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0364755 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0352053 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0351748 |
| CCNL1 | cyclin L1 | 0.0351187 |
| AREG | amphiregulin | 0.0337207 |
| TFG | TRK-fused gene | 0.0327009 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0324798 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0321247 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.031985 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0317877 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0314149 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0312627 |
| RPL21 | ribosomal protein L21 | 0.0311557 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0308711 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0306878 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0303575 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0299537 |
| CCNY | cyclin Y | 0.0299419 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0296457 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0291945 |
| NCKAP1 | NCK-associated protein 1 | 0.0291258 |
| USP6NL | USP6 N-terminal like | 0.0287978 |
| DSPP | dentin sialophosphoprotein | 0.0286892 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0283832 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0283787 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0281878 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0279292 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0277309 |
| NEK7 | NIMA-related kinase 7 | 0.0277022 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0276854 |
| FNBP1L | formin binding protein 1-like | 0.0275639 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0273544 |
| RLF | rearranged L-myc fusion | 0.0273375 |
| PNN | pinin, desmosome associated protein | 0.0271791 |
| HELZ | helicase with zinc finger | 0.0271286 |
| LRRC1 | leucine rich repeat containing 1 | 0.0269189 |
| MTF2 | metal response element binding transcription factor 2 | 0.0268238 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.0267833 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0262444 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0262205 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0260981 |
| YTHDC1 | YTH domain containing 1 | 0.0260137 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.025707 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0255331 |
| FOXJ3 | forkhead box J3 | 0.0255074 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0253569 |
| WDR43 | WD repeat domain 43 | 0.0252704 |
| ABHD17C | abhydrolase domain containing 17C | 0.024739 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0247052 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0246929 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0244347 |
| TPM3 | tropomyosin 3 | 0.0239111 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0238168 |
| ZNF654 | zinc finger protein 654 | 0.0237453 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0235874 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0234495 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.023419 |
| ATP11B | ATPase, class VI, type 11B | 0.0232758 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0232099 |
| PDS5B | PDS5 cohesin associated factor B | 0.0231703 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0228189 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0226861 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0226392 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0225868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.197377 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.174493 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.171486 |
| NPSR1 | neuropeptide S receptor 1 | -0.16677 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.120955 |
| FAT1 | FAT atypical cadherin 1 | -0.116237 |
| MYO1E | myosin IE | -0.113689 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.112476 |
| AHNAK | AHNAK nucleoprotein | -0.110182 |
| EXT1 | exostosin glycosyltransferase 1 | -0.102178 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.087326 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0854724 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0813833 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0806626 |
| PTMA | prothymosin, alpha | -0.0794806 |
| ONECUT3 | one cut homeobox 3 | -0.0779694 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0779117 |
| VCL | vinculin | -0.0755476 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0743272 |
| KRT18 | keratin 18, type I | -0.0699745 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.069239 |
| ACTG1 | actin gamma 1 | -0.0690597 |
| KRT8 | keratin 8, type II | -0.0637818 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0629435 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0629402 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0606008 |
| TPM4 | tropomyosin 4 | -0.0605585 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0597873 |
| EGFR | epidermal growth factor receptor | -0.0542624 |
| SMYD3 | SET and MYND domain containing 3 | -0.052024 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0508266 |
| POF1B | premature ovarian failure, 1B | -0.0487817 |
| TMSB10 | thymosin beta 10 | -0.04818 |
| FHIT | fragile histidine triad | -0.0479383 |
| PIGR | polymeric immunoglobulin receptor | -0.0465327 |
| AGR2 | anterior gradient 2 | -0.0460571 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0451778 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0451011 |
| CANX | calnexin | -0.0448256 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0447251 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0445309 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0437995 |
| ASPH | aspartate beta-hydroxylase | -0.0436713 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0434568 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.043442 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0432968 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0423363 |
| HDLBP | high density lipoprotein binding protein | -0.0413897 |
| CCND1 | cyclin D1 | -0.0411174 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0404192 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0398699 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0391247 |
| NEBL | nebulette | -0.0391186 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0384315 |
| RAD51B | RAD51 paralog B | -0.0382651 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0373565 |
| PALLD | palladin, cytoskeletal associated protein | -0.0371778 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0368811 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0367221 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0365027 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0351555 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0336276 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0334385 |
| DENND1A | DENN/MADD domain containing 1A | -0.033359 |
| CALR | calreticulin | -0.0330987 |
| RNF217 | ring finger protein 217 | -0.0328975 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0326703 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0326411 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0326366 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0324888 |
| TFF1 | trefoil factor 1 | -0.0322271 |
| PDLIM5 | PDZ and LIM domain 5 | -0.032023 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0318513 |
| RPS24 | ribosomal protein S24 | -0.0314958 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0313428 |
| FOXP1 | forkhead box P1 | -0.0312882 |
| H1-0 | H1.0 linker histone | -0.0312611 |
| MECOM | MDS1 and EVI1 complex locus | -0.0312395 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0311876 |
| DIAPH2 | diaphanous-related formin 2 | -0.0311532 |
| IER3 | immediate early response 3 | -0.0311227 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0310846 |
| CUX1 | cut-like homeobox 1 | -0.0309831 |
| ACTN4 | actinin, alpha 4 | -0.0303098 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0299186 |
| NFIA | nuclear factor I/A | -0.0296007 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0295559 |
| FRMD5 | FERM domain containing 5 | -0.0292351 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0287607 |
| SH3D19 | SH3 domain containing 19 | -0.0286931 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0282109 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0280809 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0277968 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0277314 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0275446 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.027235 |
| AEBP2 | AE binding protein 2 | -0.0272054 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0270965 |
| FLNB | filamin B, beta | -0.0269048 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0268991 |
