| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.0892163 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.060837 |
| LAMC2 | laminin, gamma 2 | 0.0549753 |
| RPS6 | ribosomal protein S6 | 0.0528705 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0506417 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0503825 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0503788 |
| FAM13A | family with sequence similarity 13, member A | 0.0501868 |
| RPL21 | ribosomal protein L21 | 0.0494388 |
| RPS12 | ribosomal protein S12 | 0.0468495 |
| SLMAP | sarcolemma associated protein | 0.0451201 |
| RNF145 | ring finger protein 145 | 0.0450771 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0443848 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0428615 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0423659 |
| MSN | moesin | 0.0415855 |
| ATP13A3 | ATPase type 13A3 | 0.0407898 |
| ANKRD12 | ankyrin repeat domain 12 | 0.040042 |
| SETD5 | SET domain containing 5 | 0.0388593 |
| RPS3 | ribosomal protein S3 | 0.0388389 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0383936 |
| RPS2 | ribosomal protein S2 | 0.0377763 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0373193 |
| VMP1 | vacuole membrane protein 1 | 0.0367707 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0367348 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.034914 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0345461 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.033085 |
| FOSL1 | FOS-like antigen 1 | 0.033059 |
| NGLY1 | N-glycanase 1 | 0.0329771 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0329639 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0325031 |
| TOP1 | topoisomerase (DNA) I | 0.0323987 |
| SMAD3 | SMAD family member 3 | 0.0322504 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0312514 |
| PNN | pinin, desmosome associated protein | 0.0306605 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0301135 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0290663 |
| SLTM | SAFB-like, transcription modulator | 0.0284005 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0281449 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0280256 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0280179 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0276069 |
| RASA2 | RAS p21 protein activator 2 | 0.026643 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0258088 |
| RTN4 | reticulon 4 | 0.0254963 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0254377 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0254337 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0253644 |
| RCOR1 | REST corepressor 1 | 0.0253382 |
| RBM25 | RNA binding motif protein 25 | 0.0251566 |
| S100P | S100 calcium binding protein P | 0.0251427 |
| PCBP2 | poly(rC) binding protein 2 | 0.0249312 |
| AREG | amphiregulin | 0.024715 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0246253 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0245115 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0244343 |
| SCEL | sciellin | 0.0241093 |
| MPZL2 | myelin protein zero-like 2 | 0.0237885 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0236254 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0231775 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0228684 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0226544 |
| CLU | clusterin | 0.0225357 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0224648 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.022054 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0220477 |
| TPM3 | tropomyosin 3 | 0.0217881 |
| RNF149 | ring finger protein 149 | 0.0215485 |
| TMF1 | TATA element modulatory factor 1 | 0.0212757 |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.0210761 |
| TMEM87A | transmembrane protein 87A | 0.0209043 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0208648 |
| RPS8 | ribosomal protein S8 | 0.0207433 |
| FA2H | fatty acid 2-hydroxylase | 0.0205289 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0202105 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0201326 |
| SNX9 | sorting nexin 9 | 0.0200535 |
| NUP58 | nucleoporin 58 | 0.0200386 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.019701 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0196524 |
| ANXA5 | annexin A5 | 0.0191943 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0191506 |
| MYO1D | myosin ID | 0.0191424 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0191038 |
| CDCP1 | CUB domain containing protein 1 | 0.0190115 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0189848 |
| DUSP5 | dual specificity phosphatase 5 | 0.0189241 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0187994 |
| PTK2 | protein tyrosine kinase 2 | 0.0187919 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.018628 |
| ZNF292 | zinc finger protein 292 | 0.0186177 |
| RPS17 | ribosomal protein S17 | 0.0186076 |
| ZFP36 | ZFP36 ring finger protein | 0.0184876 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0184568 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0184282 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0183444 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0183254 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0182664 |
| USP47 | ubiquitin specific peptidase 47 | 0.018233 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.205857 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161498 |
| LOC112694756 | uncharaterized LOC112694756 | -0.152295 |
| TXNRD1 | thioredoxin reductase 1 | -0.1468 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.143248 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.130705 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113117 |
| H1-0 | H1.0 linker histone | -0.105928 |
| EGFR | epidermal growth factor receptor | -0.104283 |
| TMSB10 | thymosin beta 10 | -0.0959935 |
| HDLBP | high density lipoprotein binding protein | -0.0917989 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0866882 |
| INTS6 | integrator complex subunit 6 | -0.0859632 |
| CANX | calnexin | -0.0836899 |
| PKM | pyruvate kinase, muscle | -0.0825941 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0728818 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0693517 |
| CES1 | carboxylesterase 1 | -0.0647565 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0623207 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0602126 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0597877 |
| ASPH | aspartate beta-hydroxylase | -0.0592377 |
| AHNAK | AHNAK nucleoprotein | -0.0555136 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0541848 |
| ABLIM1 | actin binding LIM protein 1 | -0.0511274 |
| PGK1 | phosphoglycerate kinase 1 | -0.0506855 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0489968 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0482318 |
| ARF1 | ADP-ribosylation factor 1 | -0.0476778 |
| LMO7 | LIM domain 7 | -0.0472282 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0460888 |
| HBP1 | HMG-box transcription factor 1 | -0.04597 |
| ANXA2 | annexin A2 | -0.0458236 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0456849 |
| RPLP1 | ribosomal protein, large, P1 | -0.0456318 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0453582 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0449754 |
| NDRG1 | N-myc downstream regulated 1 | -0.0449527 |
| PTMA | prothymosin, alpha | -0.0438589 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0428522 |
| RNF169 | ring finger protein 169 | -0.0423159 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0419583 |
| PLEC | plectin | -0.0412509 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0411909 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0409511 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0409112 |
| RPL35A | ribosomal protein L35a | -0.0404432 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0401316 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0394531 |
| MORF4L2 | mortality factor 4 like 2 | -0.0389377 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0387356 |
| RNF213 | ring finger protein 213 | -0.038505 |
| NABP1 | nucleic acid binding protein 1 | -0.0383341 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.038274 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0367689 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0363912 |
| EMP1 | epithelial membrane protein 1 | -0.0361709 |
| OGA | O-GlcNAcase | -0.0357991 |
| RPL4 | ribosomal protein L4 | -0.0355599 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0352828 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0352008 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0350688 |
| GM2A | GM2 ganglioside activator | -0.0350411 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0349501 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.034504 |
| DSCAM | Down syndrome cell adhesion molecule | -0.034072 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0334699 |
| CTBP2 | C-terminal binding protein 2 | -0.0334545 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0334343 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0333226 |
| XRRA1 | X-ray radiation resistance associated 1 | -0.0328135 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0320908 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0317744 |
| GOLGB1 | golgin B1 | -0.0317434 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0313887 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0313105 |
| TKT | transketolase | -0.0309752 |
| HYOU1 | hypoxia up-regulated 1 | -0.0309239 |
| WDR45B | WD repeat domain 45B | -0.0305649 |
| COPA | coatomer protein complex, subunit alpha | -0.0301877 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0301701 |
| USP34 | ubiquitin specific peptidase 34 | -0.0301244 |
| RPS24 | ribosomal protein S24 | -0.0295151 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0294921 |
| UBC | ubiquitin C | -0.0294596 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0293494 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0289957 |
| SUMF1 | sulfatase modifying factor 1 | -0.0289612 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0287739 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0283856 |
| CCND1 | cyclin D1 | -0.0283833 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0283086 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0281835 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0280987 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0280254 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0279059 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0277397 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0276714 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0275993 |
| SEC24D | SEC24 family member D | -0.0271279 |
