| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.115954 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.104348 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0921473 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0791398 |
| SMAD3 | SMAD family member 3 | 0.068064 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0621697 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0525228 |
| EFNA5 | ephrin-A5 | 0.0482591 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0414273 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.040956 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0409011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0387561 |
| FAM13A | family with sequence similarity 13, member A | 0.0365738 |
| SIK3 | SIK family kinase 3 | 0.0352639 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0350135 |
| ATP13A3 | ATPase type 13A3 | 0.0340777 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0336199 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0334605 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0326542 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0313939 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0313619 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0311062 |
| USP3 | ubiquitin specific peptidase 3 | 0.0306766 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0299427 |
| RNF145 | ring finger protein 145 | 0.0298956 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0286975 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0283806 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0277352 |
| CDCP1 | CUB domain containing protein 1 | 0.0277072 |
| AHR | aryl hydrocarbon receptor | 0.0274695 |
| NEK7 | NIMA-related kinase 7 | 0.0269487 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0268875 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0267319 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0265538 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0265468 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0263726 |
| HELZ | helicase with zinc finger | 0.0254559 |
| OGA | O-GlcNAcase | 0.0252687 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0251737 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0250175 |
| RPS2 | ribosomal protein S2 | 0.0240706 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0239938 |
| MT2A | metallothionein 2A | 0.023933 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.023878 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0238139 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0236463 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0231835 |
| PHIP | pleckstrin homology domain interacting protein | 0.0231093 |
| RPS12 | ribosomal protein S12 | 0.0218004 |
| PTK2 | protein tyrosine kinase 2 | 0.0215256 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0211153 |
| ZFR | zinc finger RNA binding protein | 0.0209928 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0207971 |
| RUNX1 | runt-related transcription factor 1 | 0.020606 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0204573 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0201523 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0199717 |
| IL6ST | interleukin 6 signal transducer | 0.019868 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0198119 |
| MYO6 | myosin VI | 0.0196243 |
| MSI2 | musashi RNA-binding protein 2 | 0.0195883 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0195228 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0193875 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0192952 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0191339 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0191171 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0189915 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0188082 |
| FBXO32 | F-box protein 32 | 0.0187788 |
| RASA2 | RAS p21 protein activator 2 | 0.0184348 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0184149 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0182474 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0181092 |
| DTNA | dystrobrevin, alpha | 0.0180196 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0179575 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0179192 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0178702 |
| NCKAP1 | NCK-associated protein 1 | 0.0178578 |
| XPO1 | exportin 1 | 0.0178081 |
| RARB | retinoic acid receptor, beta | 0.0177873 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0177379 |
| NAV2 | neuron navigator 2 | 0.017653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0176074 |
| WDR26 | WD repeat domain 26 | 0.0173805 |
| OTUD7B | OTU deubiquitinase 7B | 0.0171736 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0171376 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0171221 |
| PCNX1 | pecanex 1 | 0.0170913 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.016701 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.016667 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0165416 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0165309 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0162117 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0161539 |
| TXNRD1 | thioredoxin reductase 1 | 0.0161446 |
| KIAA1958 | KIAA1958 | 0.0160304 |
| STK38L | serine/threonine kinase 38 like | 0.0159891 |
| FCHO2 | FCH domain only 2 | 0.0158729 |
| RAB8B | RAB8B, member RAS oncogene family | 0.01575 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0156853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.173637 |
| LOX | lysyl oxidase | -0.154452 |
| FN1 | fibronectin 1 | -0.150923 |
| VIM | vimentin | -0.145351 |
| TMSB10 | thymosin beta 10 | -0.113687 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.104907 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.100398 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.086174 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0814178 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0813544 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0812113 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0796375 |
| SYT1 | synaptotagmin I | -0.0695701 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0692248 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0647777 |
| CDH13 | cadherin 13 | -0.0634201 |
| USP34 | ubiquitin specific peptidase 34 | -0.0609566 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0592272 |
| EGR1 | early growth response 1 | -0.0586958 |
| HMGA2 | high mobility group AT-hook 2 | -0.0556261 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0553331 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0534089 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.053298 |
| GPC6 | glypican 6 | -0.0521606 |
| FBN1 | fibrillin 1 | -0.0499525 |
| RAB1A | RAB1A, member RAS oncogene family | -0.049491 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0493153 |
| ARF4 | ADP-ribosylation factor 4 | -0.049147 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.048468 |
| DST | dystonin | -0.0482235 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0476213 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0461975 |
| COPA | coatomer protein complex, subunit alpha | -0.0456783 |
| ANKRD28 | ankyrin repeat domain 28 | -0.045464 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0452638 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0452468 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.044466 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0443013 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0442652 |
| HDLBP | high density lipoprotein binding protein | -0.0442381 |
| EHBP1 | EH domain binding protein 1 | -0.0438162 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0430237 |
| HM13 | histocompatibility (minor) 13 | -0.0429644 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0423481 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0419429 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0378172 |
| MAP1B | microtubule-associated protein 1B | -0.0377692 |
| AADAC | arylacetamide deacetylase | -0.0374956 |
| CUX1 | cut-like homeobox 1 | -0.037443 |
| HDAC9 | histone deacetylase 9 | -0.0374311 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0366079 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0359361 |
| CANX | calnexin | -0.0357796 |
| GOLGA4 | golgin A4 | -0.0353556 |
| RAI14 | retinoic acid induced 14 | -0.0352495 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0348502 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0347531 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0346939 |
| BPTF | bromodomain PHD finger transcription factor | -0.0345514 |
| S100A6 | S100 calcium binding protein A6 | -0.0341264 |
| NDRG1 | N-myc downstream regulated 1 | -0.0340671 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0338412 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.033452 |
| FNIP1 | folliculin interacting protein 1 | -0.0334414 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0334036 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0331906 |
| PTMA | prothymosin, alpha | -0.0331864 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0331834 |
| SRP54 | signal recognition particle 54kDa | -0.0328368 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0325592 |
| MYADM | myeloid-associated differentiation marker | -0.0325498 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0324952 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0322394 |
| EGFR | epidermal growth factor receptor | -0.032056 |
| SEC24A | SEC24 family member A | -0.0319743 |
| CALU | calumenin | -0.0319648 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.03182 |
| MORF4L2 | mortality factor 4 like 2 | -0.0315076 |
| NTN4 | netrin 4 | -0.0311792 |
| STC1 | stanniocalcin 1 | -0.0307701 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0306298 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0306051 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0303842 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0303492 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0302961 |
| GOLGA3 | golgin A3 | -0.0301079 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0298979 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0297993 |
| PRKCA | protein kinase C, alpha | -0.0297507 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0296172 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0295899 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0292274 |
| FTL | ferritin, light polypeptide | -0.0291196 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0291058 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.029091 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0290292 |
| ATM | ATM serine/threonine kinase | -0.0290188 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0288318 |
| SCFD1 | sec1 family domain containing 1 | -0.0287273 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0285219 |
