| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.182366 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.176976 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.138147 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0939663 |
| RNF145 | ring finger protein 145 | 0.0757546 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0751745 |
| RPS12 | ribosomal protein S12 | 0.0741851 |
| RPS2 | ribosomal protein S2 | 0.0722469 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0695243 |
| WDR43 | WD repeat domain 43 | 0.0593539 |
| RPS6 | ribosomal protein S6 | 0.0589545 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0575001 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0572018 |
| FLNB | filamin B, beta | 0.0549593 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0531187 |
| SETD5 | SET domain containing 5 | 0.0525379 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0516726 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0507791 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0506963 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0505236 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0490345 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0489785 |
| VMP1 | vacuole membrane protein 1 | 0.0453163 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0443258 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0442274 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0439414 |
| RPS3 | ribosomal protein S3 | 0.0438023 |
| RBM39 | RNA binding motif protein 39 | 0.0427191 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.041787 |
| RPS7 | ribosomal protein S7 | 0.0413447 |
| ZNF292 | zinc finger protein 292 | 0.0412773 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0405883 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0398135 |
| TPD52 | tumor protein D52 | 0.0397005 |
| TPM3 | tropomyosin 3 | 0.0388264 |
| PNN | pinin, desmosome associated protein | 0.0387304 |
| MSN | moesin | 0.0383136 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0380816 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0379823 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0375867 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0365721 |
| RPS8 | ribosomal protein S8 | 0.0365006 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0360578 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0355463 |
| RTN4 | reticulon 4 | 0.0347571 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0337114 |
| RPL37A | ribosomal protein L37a | 0.0334944 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0333051 |
| LDHA | lactate dehydrogenase A | 0.0332866 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0331916 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.032979 |
| KIF5B | kinesin family member 5B | 0.0329233 |
| PCBP2 | poly(rC) binding protein 2 | 0.032702 |
| RASAL2 | RAS protein activator like 2 | 0.0323923 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320966 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0315513 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0312848 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0310585 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0308077 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0306439 |
| GOLGA4 | golgin A4 | 0.030487 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0303306 |
| CLU | clusterin | 0.0302552 |
| SNU13 | small nuclear ribonucleoprotein 13 | 0.0297828 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0296111 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0295974 |
| HDGF | hepatoma-derived growth factor | 0.0295317 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0294345 |
| YY1 | YY1 transcription factor | 0.0292524 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0291093 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0290843 |
| RPS25 | ribosomal protein S25 | 0.0288375 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0287322 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0284102 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0283967 |
| NUP153 | nucleoporin 153kDa | 0.0282152 |
| FNBP1L | formin binding protein 1-like | 0.0281796 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0281564 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0277882 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0275959 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0271342 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0270835 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0270559 |
| BRD2 | bromodomain containing 2 | 0.0270341 |
| CABIN1 | calcineurin binding protein 1 | 0.0269725 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.026774 |
| ERBIN | erbb2 interacting protein | 0.0267285 |
| FOXN2 | forkhead box N2 | 0.0264842 |
| PYGL | phosphorylase, glycogen, liver | 0.026258 |
| SLTM | SAFB-like, transcription modulator | 0.0259988 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0257973 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0257598 |
| HELZ | helicase with zinc finger | 0.0255624 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0252259 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0251919 |
| TLK1 | tousled-like kinase 1 | 0.0251524 |
| SBF2 | SET binding factor 2 | 0.024859 |
| JMJD1C | jumonji domain containing 1C | 0.0247427 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0247402 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0247266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.304374 |
| PM20D1 | peptidase M20 domain containing 1 | -0.157609 |
| TMSB10 | thymosin beta 10 | -0.148863 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.140295 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139908 |
| TXNRD1 | thioredoxin reductase 1 | -0.124948 |
| FTL | ferritin, light polypeptide | -0.111093 |
| GRAMD1B | GRAM domain containing 1B | -0.10868 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.075855 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0687187 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0617091 |
| VIM | vimentin | -0.0595616 |
| RPLP1 | ribosomal protein, large, P1 | -0.0580816 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0564288 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0525165 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0523089 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0505595 |
| FGG | fibrinogen gamma chain | -0.0467296 |
| RPL19 | ribosomal protein L19 | -0.0460191 |
| PFN1 | profilin 1 | -0.0435642 |
| RPL35A | ribosomal protein L35a | -0.042972 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.0392962 |
| ANXA2 | annexin A2 | -0.0366331 |
| RPS20 | ribosomal protein S20 | -0.0361334 |
| WWOX | WW domain containing oxidoreductase | -0.0356697 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0349326 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0347391 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0346749 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0328826 |
| OSMR | oncostatin M receptor | -0.0328525 |
| IGF2 | insulin-like growth factor 2 | -0.0327524 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0325637 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0324938 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0324876 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0318906 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.030984 |
| MAP1B | microtubule-associated protein 1B | -0.030171 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0300744 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0299475 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0296098 |
| BICC1 | BicC family RNA binding protein 1 | -0.0290527 |
| RRM2 | ribonucleotide reductase M2 | -0.0285528 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0284338 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0280728 |
| NRG1 | neuregulin 1 | -0.0280057 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0277135 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0276988 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0276143 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0275191 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0268807 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0254405 |
| S100A10 | S100 calcium binding protein A10 | -0.0252885 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0251235 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0239564 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0235534 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0234455 |
| FUS | FUS RNA binding protein | -0.0231967 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0230516 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0226951 |
| EGR1 | early growth response 1 | -0.02261 |
| RPLP0 | ribosomal protein, large, P0 | -0.0225105 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | -0.0219939 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0216243 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0215416 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0207134 |
| ZNF804A | zinc finger protein 804A | -0.0205318 |
| TNPO1 | transportin 1 | -0.0204936 |
| NAV3 | neuron navigator 3 | -0.0203428 |
| NPR2 | natriuretic peptide receptor 2 | -0.0200969 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0198158 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0197348 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0195846 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0195012 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0193483 |
| NPTN | neuroplastin | -0.0190598 |
| AARS1 | alanyl-tRNA synthetase 1 | -0.018915 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0188234 |
| EFNA5 | ephrin-A5 | -0.0188212 |
| KYNU | kynureninase | -0.0187935 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0186592 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0183117 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0180783 |
| UPP1 | uridine phosphorylase 1 | -0.0179917 |
| SSH1 | slingshot protein phosphatase 1 | -0.0179196 |
| TTLL10 | tubulin tyrosine ligase-like family member 10 | -0.0179168 |
| RPS5 | ribosomal protein S5 | -0.0178471 |
| FGB | fibrinogen beta chain | -0.0178451 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0177354 |
| GANAB | glucosidase, alpha; neutral AB | -0.0177074 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0175862 |
| HLA-B | major histocompatibility complex, class I, B | -0.0174869 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0174573 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0172141 |
| RPS21 | ribosomal protein S21 | -0.0171538 |
| RPL34 | ribosomal protein L34 | -0.0170269 |
| H1-0 | H1.0 linker histone | -0.0166994 |
| SDC4 | syndecan 4 | -0.0166824 |
| FLNA | filamin A, alpha | -0.0166626 |
| CYTH1 | cytohesin 1 | -0.0166536 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0165102 |
