| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.107552 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.104235 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0820564 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0769003 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0687403 |
| TPI1 | triosephosphate isomerase 1 | 0.06597 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0653142 |
| TXNRD1 | thioredoxin reductase 1 | 0.0643099 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0563635 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0542788 |
| MKI67 | marker of proliferation Ki-67 | 0.0506356 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0490583 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0434492 |
| RPL23 | ribosomal protein L23 | 0.0426253 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0425752 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0419367 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0410499 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0405525 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0378897 |
| RPS2 | ribosomal protein S2 | 0.0371147 |
| KLF6 | Kruppel-like factor 6 | 0.0362274 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0359007 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0357879 |
| RPL12 | ribosomal protein L12 | 0.0351408 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0347667 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0342383 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0341875 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0334543 |
| RTN4 | reticulon 4 | 0.0325987 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.031033 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.030768 |
| DENR | density-regulated protein | 0.0306728 |
| RPS8 | ribosomal protein S8 | 0.0301241 |
| XPO1 | exportin 1 | 0.0300326 |
| IPO7 | importin 7 | 0.0295688 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0294476 |
| RPL21 | ribosomal protein L21 | 0.0287575 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0286369 |
| CIP2A | cellular inhibitor of PP2A | 0.0284901 |
| RPL11 | ribosomal protein L11 | 0.0282687 |
| TPX2 | TPX2, microtubule-associated | 0.0280957 |
| RPS7 | ribosomal protein S7 | 0.0278088 |
| CENPF | centromere protein F, 350/400kDa | 0.0277562 |
| RPS3 | ribosomal protein S3 | 0.027373 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0270701 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0270515 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0267061 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0266804 |
| SP3 | Sp3 transcription factor | 0.0266545 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0263522 |
| ZNF292 | zinc finger protein 292 | 0.0261628 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0257197 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0255593 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0252648 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0249807 |
| DIAPH3 | diaphanous-related formin 3 | 0.0248539 |
| LDHB | lactate dehydrogenase B | 0.0244498 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0243763 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0243756 |
| KIF5B | kinesin family member 5B | 0.0243627 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0242644 |
| VMP1 | vacuole membrane protein 1 | 0.0242594 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.024181 |
| PHIP | pleckstrin homology domain interacting protein | 0.0236068 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0235405 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0233419 |
| MELK | maternal embryonic leucine zipper kinase | 0.0232428 |
| MATR3 | matrin 3 | 0.0231654 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0230587 |
| SGO2 | shugoshin 2 | 0.022833 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0227419 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0227064 |
| RPS12 | ribosomal protein S12 | 0.0225497 |
| NUP153 | nucleoporin 153kDa | 0.0222967 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0222235 |
| MEMO1 | mediator of cell motility 1 | 0.0221135 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0220396 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0215507 |
| RPL18 | ribosomal protein L18 | 0.0215236 |
| CDK17 | cyclin-dependent kinase 17 | 0.0214898 |
| RPS21 | ribosomal protein S21 | 0.0214452 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0213648 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.021314 |
| TUBA1B | tubulin, alpha 1b | 0.021262 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0212533 |
| PGK1 | phosphoglycerate kinase 1 | 0.0210717 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.020618 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0206122 |
| RRM2 | ribonucleotide reductase M2 | 0.0202906 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0201996 |
| RPS16 | ribosomal protein S16 | 0.0201115 |
| CENPE | centromere protein E, 312kDa | 0.0200941 |
| KIF2C | kinesin family member 2C | 0.0200506 |
| RPS15 | ribosomal protein S15 | 0.0199442 |
| CKAP2 | cytoskeleton associated protein 2 | 0.019909 |
| GMPS | guanine monphosphate synthase | 0.0197926 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0197562 |
| ANLN | anillin, actin binding protein | 0.0197345 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0196996 |
| OGA | O-GlcNAcase | 0.0196682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.160307 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.108397 |
| COPA | coatomer protein complex, subunit alpha | -0.0869213 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0829276 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0734612 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0723695 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0716784 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0714005 |
| EGR1 | early growth response 1 | -0.0661777 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0653793 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0606199 |
| ATXN1 | ataxin 1 | -0.0599632 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0592032 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0532785 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0531217 |
| EGFR | epidermal growth factor receptor | -0.0513357 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0503269 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0496647 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0495789 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0461647 |
| PYGL | phosphorylase, glycogen, liver | -0.0453597 |
| CANX | calnexin | -0.0444231 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0441081 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0439541 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0433542 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0433496 |
| POTEF | POTE ankyrin domain family, member F | -0.0418071 |
| MCL1 | myeloid cell leukemia 1 | -0.0417912 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0408588 |
| GOLGB1 | golgin B1 | -0.0394983 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0393522 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0378975 |
| PDE10A | phosphodiesterase 10A | -0.0376566 |
| HLA-B | major histocompatibility complex, class I, B | -0.0375166 |
| OSMR | oncostatin M receptor | -0.0374332 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0374097 |
| PRKCE | protein kinase C, epsilon | -0.0373283 |
| RNF213 | ring finger protein 213 | -0.0370603 |
| HYOU1 | hypoxia up-regulated 1 | -0.0368799 |
| CALR | calreticulin | -0.0348822 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0345766 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0344047 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0332175 |
| ACTN1 | actinin, alpha 1 | -0.0331134 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0330086 |
| IGF2 | insulin-like growth factor 2 | -0.0310736 |
| TPM2 | tropomyosin 2 (beta) | -0.0308883 |
| SVIL | supervillin | -0.0308088 |
| RAD51B | RAD51 paralog B | -0.0306988 |
| TAPBP | TAP binding protein (tapasin) | -0.030622 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0302356 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0301312 |
| AEBP2 | AE binding protein 2 | -0.0301252 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0297141 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0296404 |
| RSF1 | remodeling and spacing factor 1 | -0.0290492 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0289892 |
| GPATCH2L | G patch domain containing 2-like | -0.028016 |
| HLA-A | major histocompatibility complex, class I, A | -0.0280081 |
| ZNF207 | zinc finger protein 207 | -0.0278574 |
| FLNA | filamin A, alpha | -0.0277264 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0273999 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0272442 |
| RPL35A | ribosomal protein L35a | -0.0272295 |
| PKM | pyruvate kinase, muscle | -0.0271906 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0271488 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0267079 |
| HDAC4 | histone deacetylase 4 | -0.0266937 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0264041 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0259724 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0259535 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.025605 |
| UBAP2L | ubiquitin associated protein 2-like | -0.0253824 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0252376 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0252318 |
| ATF6 | activating transcription factor 6 | -0.0250893 |
| CUX1 | cut-like homeobox 1 | -0.0249383 |
| RYR3 | ryanodine receptor 3 | -0.0248517 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0248459 |
| EXOC4 | exocyst complex component 4 | -0.0248087 |
| NBAS | neuroblastoma amplified sequence | -0.0246502 |
| FMNL2 | formin-like 2 | -0.0245392 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0244635 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.02435 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.024334 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0242132 |
| PRELID2 | PRELI domain containing 2 | -0.0241484 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0236081 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0233907 |
| INTS6 | integrator complex subunit 6 | -0.0230977 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0230737 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0230058 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.022824 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0227135 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0227044 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0224688 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0224638 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0223157 |
| GON4L | gon-4-like (C. elegans) | -0.0222624 |
| SMAD3 | SMAD family member 3 | -0.0222594 |
