| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.107078 |
| MSN | moesin | 0.0620565 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0525414 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0496327 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.044024 |
| RPS12 | ribosomal protein S12 | 0.0422841 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.042135 |
| RPS2 | ribosomal protein S2 | 0.0419997 |
| RPS6 | ribosomal protein S6 | 0.0374449 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0357254 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0353904 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0346688 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0334131 |
| HMGA1 | high mobility group AT-hook 1 | 0.0310348 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0306655 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0303278 |
| FOSL1 | FOS-like antigen 1 | 0.0275556 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0262733 |
| CENPF | centromere protein F, 350/400kDa | 0.0262413 |
| CCNL1 | cyclin L1 | 0.0255782 |
| RPL21 | ribosomal protein L21 | 0.0250761 |
| DSPP | dentin sialophosphoprotein | 0.0246785 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0230066 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0217961 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0210851 |
| ZNF292 | zinc finger protein 292 | 0.0209599 |
| MSMO1 | methylsterol monooxygenase 1 | 0.020801 |
| RNF145 | ring finger protein 145 | 0.0207895 |
| RYBP | RING1 and YY1 binding protein | 0.0207801 |
| VEGFA | vascular endothelial growth factor A | 0.0202356 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0195815 |
| MKI67 | marker of proliferation Ki-67 | 0.0194712 |
| H1-4 | H1.4 linker histone, cluster member | 0.0187494 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0179567 |
| LDHB | lactate dehydrogenase B | 0.0177817 |
| RPL5 | ribosomal protein L5 | 0.0172365 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0171224 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0163329 |
| CCNB1 | cyclin B1 | 0.0160905 |
| PNN | pinin, desmosome associated protein | 0.0159074 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0158872 |
| ANXA5 | annexin A5 | 0.0157737 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0151799 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0151102 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0143695 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0142531 |
| RACK1 | receptor for activated C kinase 1 | 0.0141416 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0141032 |
| RPLP0 | ribosomal protein, large, P0 | 0.0138216 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0137298 |
| USP3 | ubiquitin specific peptidase 3 | 0.0136727 |
| NUP58 | nucleoporin 58 | 0.0136622 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0134687 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0134022 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0131318 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0129953 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0128025 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.012697 |
| DSTN | destrin (actin depolymerizing factor) | 0.012654 |
| RPS7 | ribosomal protein S7 | 0.0126314 |
| CD83 | CD83 molecule | 0.0125319 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0124212 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.012332 |
| DUSP5 | dual specificity phosphatase 5 | 0.0122162 |
| CDK1 | cyclin-dependent kinase 1 | 0.0121794 |
| IRF1 | interferon regulatory factor 1 | 0.0121207 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0121033 |
| FHIT | fragile histidine triad | 0.0121025 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0120392 |
| AREG | amphiregulin | 0.0120093 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.011943 |
| TPX2 | TPX2, microtubule-associated | 0.0118942 |
| SET | SET nuclear proto-oncogene | 0.0118534 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0118076 |
| NRDC | nardilysin convertase | 0.0114743 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0113844 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0113666 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0113535 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0112602 |
| SSRP1 | structure specific recognition protein 1 | 0.0112542 |
| CAV2 | caveolin 2 | 0.0111077 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0109939 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0109721 |
| GLO1 | glyoxalase I | 0.0109066 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0108655 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0108606 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0108573 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0107835 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0107291 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0106747 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0106661 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0106584 |
| GOLM2 | golgi membrane protein 2 | 0.0106489 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.010635 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0106285 |
| CD24 | CD24 molecule | 0.0104783 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0104731 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0104634 |
| RPS23 | ribosomal protein S23 | 0.0104633 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.0104546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.160483 |
| UBC | ubiquitin C | -0.149352 |
| TMSB10 | thymosin beta 10 | -0.148828 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.139634 |
| LMO7 | LIM domain 7 | -0.133513 |
| PTMA | prothymosin, alpha | -0.12263 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.107067 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.106182 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.104793 |
| ACTG1 | actin gamma 1 | -0.097484 |
| TMSB4X | thymosin beta 4, X-linked | -0.0968016 |
| FN1 | fibronectin 1 | -0.0840286 |
| ASPH | aspartate beta-hydroxylase | -0.0823802 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0798281 |
| MYO6 | myosin VI | -0.0794458 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0779752 |
| ERBIN | erbb2 interacting protein | -0.0759804 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0736517 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0734473 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0690124 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0680507 |
| EFNA5 | ephrin-A5 | -0.0673331 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0671174 |
| FBXO32 | F-box protein 32 | -0.06459 |
| LAMC2 | laminin, gamma 2 | -0.0636121 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0624929 |
| S100A6 | S100 calcium binding protein A6 | -0.0623161 |
| DSCAM | Down syndrome cell adhesion molecule | -0.062018 |
| CD2AP | CD2-associated protein | -0.0618969 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0604928 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0603549 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0597272 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0595613 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0590029 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0588531 |
| COPA | coatomer protein complex, subunit alpha | -0.0564367 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0564224 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0563646 |
| HLA-A | major histocompatibility complex, class I, A | -0.0560886 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.055711 |
| PGK1 | phosphoglycerate kinase 1 | -0.0530862 |
| ANXA2 | annexin A2 | -0.0521529 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0515473 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0500876 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0494228 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0494017 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0493502 |
| AHNAK | AHNAK nucleoprotein | -0.0491813 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0487225 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0486583 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0486408 |
| FLNB | filamin B, beta | -0.0481983 |
| CALU | calumenin | -0.047795 |
| LAMB3 | laminin, beta 3 | -0.0470314 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0468627 |
| HLA-B | major histocompatibility complex, class I, B | -0.0466936 |
| TPM4 | tropomyosin 4 | -0.0466296 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0463379 |
| GNAS | GNAS complex locus | -0.0461674 |
| VCL | vinculin | -0.0460879 |
| PARD3 | par-3 family cell polarity regulator | -0.0458813 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0458783 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0457759 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0455432 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0454146 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0448207 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0447609 |
| JMJD1C | jumonji domain containing 1C | -0.0445179 |
| NF1 | neurofibromin 1 | -0.0442758 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0442694 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0438416 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0438411 |
| RASAL2 | RAS protein activator like 2 | -0.0434673 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.04325 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0430532 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0430334 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0430317 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0413649 |
| HDLBP | high density lipoprotein binding protein | -0.041323 |
| PLEC | plectin | -0.0408098 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0401676 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0401033 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0400731 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0396954 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0395272 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0395114 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0391601 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0385624 |
| S100A10 | S100 calcium binding protein A10 | -0.0385267 |
| TOP1 | topoisomerase (DNA) I | -0.0384902 |
| GOLGA4 | golgin A4 | -0.038152 |
| MCU | mitochondrial calcium uniporter | -0.0377729 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0375645 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0374701 |
| CALR | calreticulin | -0.037457 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0373785 |
| LDHA | lactate dehydrogenase A | -0.0373125 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.037285 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0372737 |
| CCND1 | cyclin D1 | -0.0372583 |
