| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS12 | ribosomal protein S12 | 0.0510495 |
| FAM13A | family with sequence similarity 13, member A | 0.0415222 |
| RPS2 | ribosomal protein S2 | 0.0412495 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0392244 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0337328 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0312046 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0303735 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0298885 |
| PCBP3 | poly(rC) binding protein 3 | 0.0289611 |
| RPL21 | ribosomal protein L21 | 0.0285095 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0275783 |
| STC1 | stanniocalcin 1 | 0.0265717 |
| RPS7 | ribosomal protein S7 | 0.0248714 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0233479 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0231043 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0230721 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0230591 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0229592 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0228952 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0205658 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0203562 |
| GOLGA4 | golgin A4 | 0.0191146 |
| RPS3 | ribosomal protein S3 | 0.0182895 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0182622 |
| RNF145 | ring finger protein 145 | 0.018132 |
| NBEAL1 | neurobeachin-like 1 | 0.0171816 |
| CRLF2 | cytokine receptor-like factor 2 | 0.0171009 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0170275 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0167738 |
| ANKRD11 | ankyrin repeat domain 11 | 0.016501 |
| CLU | clusterin | 0.0163886 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0159932 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0158325 |
| NGLY1 | N-glycanase 1 | 0.0156109 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0149814 |
| TPR | translocated promoter region, nuclear basket protein | 0.0144863 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0144577 |
| TMF1 | TATA element modulatory factor 1 | 0.0140855 |
| DNER | delta/notch-like EGF repeat containing | 0.0139318 |
| SQSTM1 | sequestosome 1 | 0.0139108 |
| RPS8 | ribosomal protein S8 | 0.0131488 |
| TMEM165 | transmembrane protein 165 | 0.0130606 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0129356 |
| ZNF638 | zinc finger protein 638 | 0.0129331 |
| VMP1 | vacuole membrane protein 1 | 0.0127386 |
| FNIP1 | folliculin interacting protein 1 | 0.0124985 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0122663 |
| RPL23A | ribosomal protein L23a | 0.0121432 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0120728 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0119168 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0116601 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.011597 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0114942 |
| YBX3 | Y box binding protein 3 | 0.0114629 |
| DENR | density-regulated protein | 0.0113667 |
| ARFGEF3 | ARFGEF family member 3 | 0.0113586 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0113052 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.011207 |
| RYR2 | ryanodine receptor 2 (cardiac) | 0.0111688 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.011128 |
| BMERB1 | bMERB domain containing 1 | 0.0110466 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0110408 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0110204 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.011014 |
| PGM3 | phosphoglucomutase 3 | 0.0108301 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0106376 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0105023 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0104567 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0103151 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0102539 |
| MLKL | mixed lineage kinase domain-like | 0.010203 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0101072 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.010066 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00999979 |
| KAZN | kazrin, periplakin interacting protein | 0.00992759 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.00991632 |
| SLC16A6 | solute carrier family 16, member 6 | 0.00988279 |
| DENND1A | DENN/MADD domain containing 1A | 0.00984774 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00982012 |
| H1-2 | H1.2 linker histone, cluster member | 0.00972183 |
| H1-4 | H1.4 linker histone, cluster member | 0.00957532 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0094824 |
| ATG7 | autophagy related 7 | 0.0094418 |
| XBP1 | X-box binding protein 1 | 0.00929556 |
| RNF24 | ring finger protein 24 | 0.00927107 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.00925015 |
| TENM2 | teneurin transmembrane protein 2 | 0.00922816 |
| ZNF292 | zinc finger protein 292 | 0.00922319 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.00912549 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00905495 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.00905247 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.00904321 |
| SETD5 | SET domain containing 5 | 0.00902127 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.00899566 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.00898385 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00895235 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.00892986 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.00885974 |
| RIGI | RNA sensor RIG-I | 0.0088235 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0088094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.163508 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157838 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.136532 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130174 |
| ASPH | aspartate beta-hydroxylase | -0.129112 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.123729 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.115138 |
| GDA | guanine deaminase | -0.110063 |
| COL5A2 | collagen, type V, alpha 2 | -0.0880191 |
| TMSB10 | thymosin beta 10 | -0.0863461 |
| FTL | ferritin, light polypeptide | -0.0816948 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0809351 |
| PDE10A | phosphodiesterase 10A | -0.0806019 |
| RPLP1 | ribosomal protein, large, P1 | -0.0765734 |
| MYOF | myoferlin | -0.0764399 |
| SLC38A2 | solute carrier family 38, member 2 | -0.076139 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0719694 |
| PTMA | prothymosin, alpha | -0.0718068 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0684245 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0682255 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0644669 |
| GRAMD1B | GRAM domain containing 1B | -0.0604206 |
| NRCAM | neuronal cell adhesion molecule | -0.0603351 |
| DST | dystonin | -0.060224 |
| VIM | vimentin | -0.0582405 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0573225 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0558305 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0555845 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0542001 |
| RPL35A | ribosomal protein L35a | -0.0534636 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0533636 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0525971 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0525421 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0519961 |
| RPS24 | ribosomal protein S24 | -0.0517835 |
| NEK7 | NIMA-related kinase 7 | -0.0512384 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0508911 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0502842 |
| TNPO1 | transportin 1 | -0.0498073 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0491612 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.049095 |
| FN1 | fibronectin 1 | -0.0489293 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0480283 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0472872 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0469777 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0465682 |
| RPLP0 | ribosomal protein, large, P0 | -0.0459946 |
| RTN4 | reticulon 4 | -0.0455647 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0445279 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0443407 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0442142 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0434409 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0415159 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0414528 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0410318 |
| CANX | calnexin | -0.0391915 |
| MAP1B | microtubule-associated protein 1B | -0.0386077 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0384745 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0378286 |
| UBC | ubiquitin C | -0.0378059 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0376684 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0363428 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0357361 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0357012 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0354223 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0348197 |
| CDK6 | cyclin-dependent kinase 6 | -0.0347982 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0341589 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0338273 |
| PALLD | palladin, cytoskeletal associated protein | -0.0337005 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0334964 |
| SMYD3 | SET and MYND domain containing 3 | -0.0334833 |
| PKM | pyruvate kinase, muscle | -0.0333112 |
| JMJD1C | jumonji domain containing 1C | -0.0332876 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0329447 |
| EZR | ezrin | -0.0329298 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0325009 |
| ACTG1 | actin gamma 1 | -0.0323449 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0321256 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0307268 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0304863 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0304435 |
| RPS4X | ribosomal protein S4, X-linked | -0.0303669 |
| ENAH | enabled homolog (Drosophila) | -0.0299566 |
| NDRG1 | N-myc downstream regulated 1 | -0.0295744 |
| PTEN | phosphatase and tensin homolog | -0.0295689 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0290749 |
| MCL1 | myeloid cell leukemia 1 | -0.0288239 |
| LDHA | lactate dehydrogenase A | -0.0286682 |
| TUSC3 | tumor suppressor candidate 3 | -0.0285464 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0281987 |
| PCBP2 | poly(rC) binding protein 2 | -0.0280427 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0279474 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0277722 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0276624 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0276286 |
| RPS23 | ribosomal protein S23 | -0.0275755 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0275653 |
| YBX1 | Y box binding protein 1 | -0.0274439 |
| PTGR1 | prostaglandin reductase 1 | -0.0271779 |
