| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.12452 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.118597 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0927107 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0875296 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0855016 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0823391 |
| ZNF292 | zinc finger protein 292 | 0.0801208 |
| SRP54 | signal recognition particle 54kDa | 0.0719734 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0676502 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0672619 |
| H1-4 | H1.4 linker histone, cluster member | 0.0658196 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0644598 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0633321 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0607627 |
| RPS12 | ribosomal protein S12 | 0.0598686 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0589296 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0585271 |
| SPAG9 | sperm associated antigen 9 | 0.0574299 |
| B2M | beta-2-microglobulin | 0.0554395 |
| RPS2 | ribosomal protein S2 | 0.0544875 |
| RPS16 | ribosomal protein S16 | 0.0540063 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0534308 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0530342 |
| FBXO11 | F-box protein 11 | 0.0524523 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.052005 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0512106 |
| DENND4C | DENN/MADD domain containing 4C | 0.0510102 |
| QKI | QKI, KH domain containing, RNA binding | 0.0486124 |
| CFL2 | cofilin 2 (muscle) | 0.0483901 |
| RPL21 | ribosomal protein L21 | 0.0467237 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0467124 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0466375 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0462776 |
| USP3 | ubiquitin specific peptidase 3 | 0.0449286 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0445614 |
| RPL5 | ribosomal protein L5 | 0.0442348 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0438177 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0437662 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0436331 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.042917 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.042745 |
| TPX2 | TPX2, microtubule-associated | 0.0422051 |
| WDR43 | WD repeat domain 43 | 0.0420767 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0419722 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0419425 |
| CENPF | centromere protein F, 350/400kDa | 0.0418728 |
| MB21D2 | Mab-21 domain containing 2 | 0.0417762 |
| MTF2 | metal response element binding transcription factor 2 | 0.0416286 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0414143 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0405783 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0404981 |
| H1-2 | H1.2 linker histone, cluster member | 0.0396873 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0395746 |
| JMJD1C | jumonji domain containing 1C | 0.0392631 |
| DSTN | destrin (actin depolymerizing factor) | 0.0391367 |
| ZFP36 | ZFP36 ring finger protein | 0.038754 |
| PCBP2 | poly(rC) binding protein 2 | 0.0383202 |
| NOP58 | NOP58 ribonucleoprotein | 0.0382633 |
| PDS5A | PDS5 cohesin associated factor A | 0.0381209 |
| DST | dystonin | 0.038003 |
| MBIP | MAP3K12 binding inhibitory protein 1 | 0.0372571 |
| XPO1 | exportin 1 | 0.0369404 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0368585 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0368214 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.036501 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0364329 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0356051 |
| ATG5 | autophagy related 5 | 0.0354799 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0354138 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0352824 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0349447 |
| COLEC11 | collectin sub-family member 11 | 0.034824 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0347722 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0347179 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0346513 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0344658 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0343563 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.034193 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0336369 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0336107 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.03332 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0329984 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.032906 |
| NCKAP1 | NCK-associated protein 1 | 0.0328872 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0328131 |
| CCDC88A | coiled-coil domain containing 88A | 0.0326875 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0326189 |
| SSRP1 | structure specific recognition protein 1 | 0.0326127 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0322717 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0322487 |
| CBX5 | chromobox homolog 5 | 0.0322109 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0319462 |
| PAPOLA | poly(A) polymerase alpha | 0.0317205 |
| HELZ | helicase with zinc finger | 0.0315295 |
| OPHN1 | oligophrenin 1 | 0.0314545 |
| VMP1 | vacuole membrane protein 1 | 0.0313277 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0312548 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0307926 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0306634 |
| MSN | moesin | 0.0306321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.180638 |
| CADM2 | cell adhesion molecule 2 | -0.142733 |
| COL5A2 | collagen, type V, alpha 2 | -0.106204 |
| PCDH9 | protocadherin 9 | -0.100128 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0925061 |
| VIM | vimentin | -0.0700454 |
| NTM | neurotrimin | -0.0659135 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.06532 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.062994 |
| CDH19 | cadherin 19, type 2 | -0.0611184 |
| THBS1 | thrombospondin 1 | -0.059178 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0566689 |
| RPLP1 | ribosomal protein, large, P1 | -0.0557046 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0555442 |
| ACTG1 | actin gamma 1 | -0.0550019 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0540514 |
| TENM3 | teneurin transmembrane protein 3 | -0.0528639 |
| TMSB4X | thymosin beta 4, X-linked | -0.0514059 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0513202 |
| RASAL2 | RAS protein activator like 2 | -0.050889 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0496283 |
| GPC3 | glypican 3 | -0.0475977 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0467038 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0441875 |
| FOXP2 | forkhead box P2 | -0.0433857 |
| LRRC4C | leucine rich repeat containing 4C | -0.0429023 |
| RPS24 | ribosomal protein S24 | -0.042828 |
| TMSB10 | thymosin beta 10 | -0.042349 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.041554 |
| PCDH7 | protocadherin 7 | -0.040061 |
| RAD51B | RAD51 paralog B | -0.0396972 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0396686 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0391624 |
| AHNAK | AHNAK nucleoprotein | -0.0390586 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0386925 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0379299 |
| ACTN4 | actinin, alpha 4 | -0.0376438 |
| COL3A1 | collagen, type III, alpha 1 | -0.0367697 |
| PROS1 | protein S (alpha) | -0.0366292 |
| VCL | vinculin | -0.03644 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0359491 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0356231 |
| MEIS2 | Meis homeobox 2 | -0.035574 |
| MPG | N-methylpurine-DNA glycosylase | -0.0350825 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0345211 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0338668 |
| BSG | basigin (Ok blood group) | -0.0334422 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.033047 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0330324 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0325127 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0317774 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0316916 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0314641 |
| DEK | DEK proto-oncogene | -0.0310419 |
| POU3F2 | POU class 3 homeobox 2 | -0.0310363 |
| TJP1 | tight junction protein 1 | -0.030753 |
| FLNA | filamin A, alpha | -0.0305995 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0305221 |
| CAVIN1 | caveolae associated protein 1 | -0.0302786 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0300003 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0297377 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0294104 |
| PLCB4 | phospholipase C, beta 4 | -0.029389 |
| SSH2 | slingshot protein phosphatase 2 | -0.0288915 |
| PARD3B | par-3 family cell polarity regulator beta | -0.02885 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0284204 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0283805 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | -0.0283606 |
| TXNRD1 | thioredoxin reductase 1 | -0.0278394 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0275186 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0274408 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0273039 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | -0.0272999 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0264496 |
| ACACA | acetyl-CoA carboxylase alpha | -0.02641 |
| RPL27A | ribosomal protein L27a | -0.0262497 |
| RPS19 | ribosomal protein S19 | -0.0262461 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0259324 |
| STAG2 | stromal antigen 2 | -0.0259058 |
| UBTF | upstream binding transcription factor, RNA polymerase I | -0.0258628 |
| EPHA5 | EPH receptor A5 | -0.0257563 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0254545 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0253771 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0252485 |
| RPLP0 | ribosomal protein, large, P0 | -0.0251003 |
| HDAC8 | histone deacetylase 8 | -0.0250509 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0247539 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0247373 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0247055 |
| SRP72 | signal recognition particle 72kDa | -0.0245606 |
| PRELID2 | PRELI domain containing 2 | -0.0245427 |
| PARK7 | parkinson protein 7 | -0.0241447 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0240804 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0240643 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0240469 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0237027 |
| MED12L | mediator complex subunit 12-like | -0.0236852 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0236312 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0235865 |
| NF1 | neurofibromin 1 | -0.0231895 |
