| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFP36 | ZFP36 ring finger protein | 0.163497 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.161693 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0794151 |
| RPS2 | ribosomal protein S2 | 0.0739179 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0730158 |
| RPS12 | ribosomal protein S12 | 0.0617931 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.060203 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0548632 |
| RPS16 | ribosomal protein S16 | 0.0514205 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0493525 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0462603 |
| SNX14 | sorting nexin 14 | 0.0458387 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0444895 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.044421 |
| ATP13A3 | ATPase type 13A3 | 0.0439865 |
| RPL21 | ribosomal protein L21 | 0.0435508 |
| RPS3 | ribosomal protein S3 | 0.0431534 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.043016 |
| GOLGA4 | golgin A4 | 0.0419124 |
| RPLP2 | ribosomal protein, large, P2 | 0.0403138 |
| VMP1 | vacuole membrane protein 1 | 0.0402753 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0400574 |
| ZNF292 | zinc finger protein 292 | 0.0397344 |
| FOSL1 | FOS-like antigen 1 | 0.0388351 |
| WDR43 | WD repeat domain 43 | 0.0386994 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0380548 |
| SET | SET nuclear proto-oncogene | 0.0364763 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0345608 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0345586 |
| TMEM41B | transmembrane protein 41B | 0.0339972 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0334444 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0333454 |
| SPAG9 | sperm associated antigen 9 | 0.03332 |
| MATR3 | matrin 3 | 0.0331095 |
| RNF145 | ring finger protein 145 | 0.0320217 |
| OGA | O-GlcNAcase | 0.0314876 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0310488 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0305482 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0302181 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0301378 |
| ARRDC3 | arrestin domain containing 3 | 0.030135 |
| RPS8 | ribosomal protein S8 | 0.0300551 |
| SMAD3 | SMAD family member 3 | 0.0299315 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0292814 |
| DSTN | destrin (actin depolymerizing factor) | 0.0286875 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0281484 |
| NOP58 | NOP58 ribonucleoprotein | 0.0278181 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0277426 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0276377 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0275252 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0272512 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0270676 |
| RPS7 | ribosomal protein S7 | 0.0267312 |
| SETD5 | SET domain containing 5 | 0.0264947 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0264121 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0259361 |
| IMMT | inner membrane protein, mitochondrial | 0.0258107 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0257575 |
| SUCO | SUN domain containing ossification factor | 0.025603 |
| MSN | moesin | 0.0253898 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0253426 |
| RPL11 | ribosomal protein L11 | 0.0247397 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0244367 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0242514 |
| SRP54 | signal recognition particle 54kDa | 0.023814 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0238132 |
| NUP153 | nucleoporin 153kDa | 0.0237348 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0235236 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0233899 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0233848 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0233108 |
| H1-4 | H1.4 linker histone, cluster member | 0.0232967 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0228726 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0228332 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0225887 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0223681 |
| SERF2 | small EDRK-rich factor 2 | 0.0222975 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0220842 |
| DENR | density-regulated protein | 0.021647 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.021368 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0213273 |
| RACK1 | receptor for activated C kinase 1 | 0.0208049 |
| WDR26 | WD repeat domain 26 | 0.0207027 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0207023 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.020567 |
| RPL37A | ribosomal protein L37a | 0.0204138 |
| SP3 | Sp3 transcription factor | 0.0202847 |
| NUP58 | nucleoporin 58 | 0.0202643 |
| JMJD1C | jumonji domain containing 1C | 0.0200807 |
| RLF | rearranged L-myc fusion | 0.0198355 |
| SLMAP | sarcolemma associated protein | 0.0197885 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0195939 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0194895 |
| RPS25 | ribosomal protein S25 | 0.0192955 |
| KLF6 | Kruppel-like factor 6 | 0.0192067 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0190684 |
| XPO1 | exportin 1 | 0.0190231 |
| USP3 | ubiquitin specific peptidase 3 | 0.0189725 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0189376 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0189187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.158235 |
| VIM | vimentin | -0.149713 |
| AHNAK | AHNAK nucleoprotein | -0.10408 |
| SLC35F3 | solute carrier family 35, member F3 | -0.101126 |
| ACTN4 | actinin, alpha 4 | -0.0977926 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0944466 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0900493 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0863184 |
| TMSB10 | thymosin beta 10 | -0.082432 |
| EGFR | epidermal growth factor receptor | -0.081804 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0802151 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0738177 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0679503 |
| DST | dystonin | -0.06726 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0613619 |
| RPL35A | ribosomal protein L35a | -0.0586941 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0569688 |
| INTS6 | integrator complex subunit 6 | -0.052311 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0519167 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0505641 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0498301 |
| MAP1B | microtubule-associated protein 1B | -0.0497475 |
| RNF213 | ring finger protein 213 | -0.0492154 |
| TNS3 | tensin 3 | -0.0491388 |
| PKM | pyruvate kinase, muscle | -0.0486932 |
| CTSD | cathepsin D | -0.0478339 |
| TPM1 | tropomyosin 1 (alpha) | -0.0470222 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0470186 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0468411 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0468332 |
| EGR1 | early growth response 1 | -0.0459951 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0453751 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0446891 |
| PTK2 | protein tyrosine kinase 2 | -0.043203 |
| EHBP1 | EH domain binding protein 1 | -0.0425633 |
| RASAL2 | RAS protein activator like 2 | -0.0425268 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0424328 |
| MYO1E | myosin IE | -0.0402844 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0400032 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0396654 |
| ZNF780B | zinc finger protein 780B | -0.039549 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0394861 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0389477 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0386969 |
| EXOC4 | exocyst complex component 4 | -0.0384589 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0379984 |
| TMEM123 | transmembrane protein 123 | -0.0376568 |
| SFTPA2 | surfactant protein A2 | -0.0375528 |
| CANX | calnexin | -0.0372677 |
| ATG7 | autophagy related 7 | -0.0371264 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.03676 |
| ATXN1 | ataxin 1 | -0.0364006 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0353797 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0352183 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.035166 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0340237 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0339453 |
| ATM | ATM serine/threonine kinase | -0.0337391 |
| CBX3 | chromobox homolog 3 | -0.033739 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0337336 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0331265 |
| ZNF407 | zinc finger protein 407 | -0.033011 |
| HMGA2 | high mobility group AT-hook 2 | -0.0330078 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0326698 |
| NUP98 | nucleoporin 98kDa | -0.0323763 |
| DIAPH2 | diaphanous-related formin 2 | -0.0323002 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0321035 |
| RNF220 | ring finger protein 220 | -0.032014 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0318876 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0314693 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0310652 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0306536 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0306389 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0304554 |
| MYOF | myoferlin | -0.0300406 |
| L1CAM | L1 cell adhesion molecule | -0.0299421 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0296159 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0295886 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0293884 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0292757 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0292016 |
| TCF12 | transcription factor 12 | -0.0290232 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0289865 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0289794 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0286693 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0286016 |
| MED29 | mediator complex subunit 29 | -0.028495 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.028336 |
| NF1 | neurofibromin 1 | -0.0281969 |
| ACTG1 | actin gamma 1 | -0.0279132 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0271386 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.026964 |
| PHF14 | PHD finger protein 14 | -0.026675 |
| UBAP2 | ubiquitin associated protein 2 | -0.026443 |
| ZNF546 | zinc finger protein 546 | -0.0264414 |
| FLNA | filamin A, alpha | -0.0263169 |
| LDHA | lactate dehydrogenase A | -0.0262219 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0262083 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0258512 |
| ATP9B | ATPase, class II, type 9B | -0.0256827 |
