| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.100718 |
| STC1 | stanniocalcin 1 | 0.100505 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0809461 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0714289 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0582057 |
| TXNRD1 | thioredoxin reductase 1 | 0.0542318 |
| AHNAK | AHNAK nucleoprotein | 0.0525048 |
| USP3 | ubiquitin specific peptidase 3 | 0.0510469 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.046844 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0445018 |
| STK4 | serine/threonine kinase 4 | 0.0423541 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0415031 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0408036 |
| RPL23 | ribosomal protein L23 | 0.0406307 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0388 |
| MKI67 | marker of proliferation Ki-67 | 0.037817 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0375559 |
| ENO1 | enolase 1, (alpha) | 0.0367259 |
| NCKAP1 | NCK-associated protein 1 | 0.0342329 |
| CDK17 | cyclin-dependent kinase 17 | 0.0336027 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0333148 |
| RPL26 | ribosomal protein L26 | 0.0331557 |
| MTAP | methylthioadenosine phosphorylase | 0.0328947 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0327016 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0323002 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0322265 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0312701 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0305601 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303978 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0303819 |
| ATP13A3 | ATPase type 13A3 | 0.0301201 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0291898 |
| FHL2 | four and a half LIM domains 2 | 0.0291187 |
| S100A2 | S100 calcium binding protein A2 | 0.0290577 |
| KIF5B | kinesin family member 5B | 0.0290064 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0288914 |
| TPX2 | TPX2, microtubule-associated | 0.0286291 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0284934 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0284739 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0280325 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.027389 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0272801 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0272098 |
| TEX10 | testis expressed 10 | 0.0271294 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0269936 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0269233 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0268143 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0266814 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0265322 |
| WDR43 | WD repeat domain 43 | 0.0264465 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0263863 |
| RPL12 | ribosomal protein L12 | 0.026339 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.0262368 |
| CDC73 | cell division cycle 73 | 0.0261272 |
| MTF2 | metal response element binding transcription factor 2 | 0.0261185 |
| RBM39 | RNA binding motif protein 39 | 0.0261084 |
| ECT2 | epithelial cell transforming 2 | 0.0260477 |
| RASA2 | RAS p21 protein activator 2 | 0.0256416 |
| RPL11 | ribosomal protein L11 | 0.0256403 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0254407 |
| MTPN | myotrophin | 0.0250967 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0248342 |
| PGK1 | phosphoglycerate kinase 1 | 0.0247718 |
| OTUD4 | OTU deubiquitinase 4 | 0.0247146 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0246776 |
| RPL21 | ribosomal protein L21 | 0.0245533 |
| SNX9 | sorting nexin 9 | 0.0243381 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237506 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0237309 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0237005 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0236209 |
| YME1L1 | YME1-like 1 ATPase | 0.0232577 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0230439 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.0228743 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0228263 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0227922 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0226698 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0225782 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0223897 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.0223687 |
| H1-4 | H1.4 linker histone, cluster member | 0.022232 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0220123 |
| G0S2 | G0/G1 switch 2 | 0.021996 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0219475 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0219457 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0219151 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0218171 |
| SLC35F2 | solute carrier family 35, member F2 | 0.0218105 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0214568 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0212947 |
| RPL5 | ribosomal protein L5 | 0.0212722 |
| PTCD3 | pentatricopeptide repeat domain 3 | 0.0211971 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0211657 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0210647 |
| ABI1 | abl-interactor 1 | 0.0210474 |
| RPS2 | ribosomal protein S2 | 0.0210403 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0210378 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.0209519 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.020808 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0207668 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HDAC9 | histone deacetylase 9 | -0.231108 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.156841 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.156397 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.146135 |
| FRMD6 | FERM domain containing 6 | -0.126587 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.113105 |
| FLNB | filamin B, beta | -0.105998 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.100127 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0980843 |
| FRMD4A | FERM domain containing 4A | -0.0960659 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0956659 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.091764 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0883992 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0795518 |
| NAV3 | neuron navigator 3 | -0.0792236 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0787382 |
| ZNF438 | zinc finger protein 438 | -0.0779293 |
| FTL | ferritin, light polypeptide | -0.0777499 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0763482 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0712678 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0712434 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0711316 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.070218 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0663568 |
| GOLGA4 | golgin A4 | -0.0656507 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0628958 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0604764 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0600767 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.058805 |
| NDRG1 | N-myc downstream regulated 1 | -0.0586417 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0581249 |
| NABP1 | nucleic acid binding protein 1 | -0.0581182 |
| CALD1 | caldesmon 1 | -0.0555949 |
| BNC2 | basonuclin 2 | -0.0554598 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0527976 |
| FNIP1 | folliculin interacting protein 1 | -0.0525743 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.051732 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0515905 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0514532 |
| DENND1A | DENN/MADD domain containing 1A | -0.0481745 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0477976 |
| JMJD1C | jumonji domain containing 1C | -0.0471932 |
| PCNX4 | pecanex 4 | -0.0467862 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.046128 |
| CANX | calnexin | -0.0449724 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0446316 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0430088 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0422765 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0410212 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0405281 |
| CUX1 | cut-like homeobox 1 | -0.0401321 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0391146 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0389011 |
| CAST | calpastatin | -0.0388928 |
| INTS6 | integrator complex subunit 6 | -0.0384007 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0380543 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0380441 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.037886 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0375973 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.036515 |
| RPL35A | ribosomal protein L35a | -0.0364825 |
| CALU | calumenin | -0.0360298 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0358042 |
| MROH1 | maestro heat-like repeat family member 1 | -0.035599 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0354056 |
| SEC24A | SEC24 family member A | -0.0353681 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0353413 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.035265 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0349472 |
| DGKI | diacylglycerol kinase, iota | -0.0348926 |
| RPS6 | ribosomal protein S6 | -0.0348925 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | -0.0347717 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0347352 |
| XPC | xeroderma pigmentosum, complementation group C | -0.0346788 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0346141 |
| HM13 | histocompatibility (minor) 13 | -0.0345828 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0345802 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0342576 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.034155 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0340646 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.033897 |
| LATS2 | large tumor suppressor kinase 2 | -0.0338814 |
| EGR1 | early growth response 1 | -0.0336462 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0334146 |
| KPNB1 | karyopherin (importin) beta 1 | -0.033056 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0330218 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0329498 |
| HLA-A | major histocompatibility complex, class I, A | -0.0319541 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0316858 |
| RRBP1 | ribosome binding protein 1 | -0.0314394 |
| PRKCE | protein kinase C, epsilon | -0.0313984 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0313699 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0310196 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0308795 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.0307497 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0304182 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0303786 |
| RAD51B | RAD51 paralog B | -0.0303768 |
| PARD3 | par-3 family cell polarity regulator | -0.0303075 |
| MTDH | metadherin | -0.0300838 |
