| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.114415 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.110037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0874774 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0801121 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0756362 |
| VEGFA | vascular endothelial growth factor A | 0.0743446 |
| HLA-B | major histocompatibility complex, class I, B | 0.0705323 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0680298 |
| B2M | beta-2-microglobulin | 0.0657356 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.064964 |
| ENO1 | enolase 1, (alpha) | 0.0563125 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0544598 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0525842 |
| UBC | ubiquitin C | 0.0522727 |
| POTEF | POTE ankyrin domain family, member F | 0.0522044 |
| ZNF292 | zinc finger protein 292 | 0.0520236 |
| MSN | moesin | 0.0494727 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0462098 |
| CENPF | centromere protein F, 350/400kDa | 0.0444237 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0436588 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0435732 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0433844 |
| COL1A2 | collagen, type I, alpha 2 | 0.0429688 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0411388 |
| ASPH | aspartate beta-hydroxylase | 0.041108 |
| PCBP2 | poly(rC) binding protein 2 | 0.0389591 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0382998 |
| PTMA | prothymosin, alpha | 0.037185 |
| FAM13A | family with sequence similarity 13, member A | 0.0370154 |
| CDH13 | cadherin 13 | 0.0349981 |
| SUCO | SUN domain containing ossification factor | 0.0349046 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0344458 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0335386 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0328575 |
| IL1B | interleukin 1, beta | 0.0326167 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.032404 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0321467 |
| TPM1 | tropomyosin 1 (alpha) | 0.0318087 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0317201 |
| MCL1 | myeloid cell leukemia 1 | 0.031154 |
| ANLN | anillin, actin binding protein | 0.0310385 |
| RPS27A | ribosomal protein S27a | 0.0310369 |
| WTAP | Wilms tumor 1 associated protein | 0.0309072 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0305377 |
| NUP58 | nucleoporin 58 | 0.0293126 |
| HLA-A | major histocompatibility complex, class I, A | 0.0291218 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0284942 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.0277991 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0277644 |
| RYBP | RING1 and YY1 binding protein | 0.0277367 |
| PTK2 | protein tyrosine kinase 2 | 0.0274913 |
| MATR3 | matrin 3 | 0.027127 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0270392 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270214 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0269152 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0268254 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0267025 |
| MTSS1 | metastasis suppressor 1 | 0.026698 |
| USP3 | ubiquitin specific peptidase 3 | 0.0266892 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0266253 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0265006 |
| PKM | pyruvate kinase, muscle | 0.0262947 |
| FOSL1 | FOS-like antigen 1 | 0.02627 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0262373 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.025681 |
| HDAC9 | histone deacetylase 9 | 0.0255508 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0253374 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0250552 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0250104 |
| NCKAP1 | NCK-associated protein 1 | 0.0249818 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0248393 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0246671 |
| TGM2 | transglutaminase 2 | 0.0246565 |
| COLEC11 | collectin sub-family member 11 | 0.0243942 |
| RPS12 | ribosomal protein S12 | 0.0243688 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0243573 |
| ARRDC3 | arrestin domain containing 3 | 0.024242 |
| COL1A1 | collagen, type I, alpha 1 | 0.0242289 |
| XPO1 | exportin 1 | 0.0239235 |
| CALR | calreticulin | 0.0237122 |
| NAV2 | neuron navigator 2 | 0.0236788 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0236476 |
| CCNL1 | cyclin L1 | 0.0232905 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0229921 |
| INHBA | inhibin, beta A | 0.0228123 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0227721 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0226307 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0225001 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0222384 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0220115 |
| FBXO32 | F-box protein 32 | 0.0219755 |
| ARF4 | ADP-ribosylation factor 4 | 0.021958 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0218356 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0218347 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.021779 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0217352 |
| RHOA | ras homolog family member A | 0.021485 |
| MMP12 | matrix metallopeptidase 12 | 0.0214027 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0213523 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0212244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.241745 |
| VIM | vimentin | -0.0896599 |
| FRMD4A | FERM domain containing 4A | -0.0786301 |
| MT2A | metallothionein 2A | -0.0769569 |
| CD44 | CD44 molecule (Indian blood group) | -0.0674484 |
| HPCAL1 | hippocalcin-like 1 | -0.0548849 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0548375 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.047603 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0474098 |
| TNNC1 | troponin C type 1 (slow) | -0.0445482 |
| NRP1 | neuropilin 1 | -0.0442143 |
| HMGA2 | high mobility group AT-hook 2 | -0.0411614 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0401022 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0392813 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0379253 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0369143 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0348914 |
| GNAS | GNAS complex locus | -0.0340127 |
| H1-0 | H1.0 linker histone | -0.0338934 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0334456 |
| VCL | vinculin | -0.0330141 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0327064 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0320275 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0320068 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0315327 |
| NF1 | neurofibromin 1 | -0.0313003 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.03095 |
| PCBP3 | poly(rC) binding protein 3 | -0.0300782 |
| COL5A3 | collagen, type V, alpha 3 | -0.0298721 |
| PGK1 | phosphoglycerate kinase 1 | -0.029768 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0292951 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.02909 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.029052 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0287402 |
| SVIL | supervillin | -0.0284636 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0280868 |
| RSU1 | Ras suppressor protein 1 | -0.0275259 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0272386 |
| FHL2 | four and a half LIM domains 2 | -0.0270919 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0269644 |
| TMEM178B | transmembrane protein 178B | -0.0267358 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0266768 |
| GLIS3 | GLIS family zinc finger 3 | -0.0265946 |
| HM13 | histocompatibility (minor) 13 | -0.0265153 |
| SCFD1 | sec1 family domain containing 1 | -0.0262908 |
| PAX3 | paired box 3 | -0.0262297 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.026042 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0259605 |
| GOLGB1 | golgin B1 | -0.025872 |
| MAP1B | microtubule-associated protein 1B | -0.0256502 |
| RRBP1 | ribosome binding protein 1 | -0.0248547 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0245699 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.024468 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0243597 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0240316 |
| NBEAL1 | neurobeachin-like 1 | -0.0237601 |
| PHF14 | PHD finger protein 14 | -0.023067 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0229905 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0228027 |
| LOX | lysyl oxidase | -0.0225987 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0225619 |
| OSMR | oncostatin M receptor | -0.0223005 |
| GPR173 | G protein-coupled receptor 173 | -0.0220582 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0218821 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0214434 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0209656 |
| BPTF | bromodomain PHD finger transcription factor | -0.0208846 |
| RNF213 | ring finger protein 213 | -0.020865 |
| ACTG1 | actin gamma 1 | -0.0205287 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0204789 |
| HDLBP | high density lipoprotein binding protein | -0.0204385 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0204231 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0203975 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.020363 |
| RTF2 | replication termination factor 2 | -0.0203106 |
| CCDC102B | coiled-coil domain containing 102B | -0.0202423 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.0199982 |
| PALLD | palladin, cytoskeletal associated protein | -0.0199072 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0194717 |
| FBXO11 | F-box protein 11 | -0.0194249 |
| RORA | RAR-related orphan receptor A | -0.0193967 |
| ATXN2 | ataxin 2 | -0.0192938 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0191691 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0191345 |
| SUMF1 | sulfatase modifying factor 1 | -0.0190987 |
| ZNF644 | zinc finger protein 644 | -0.0190686 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.018756 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0186628 |
| RUNX2 | runt-related transcription factor 2 | -0.0186044 |
| GOLGA3 | golgin A3 | -0.0180992 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.01798 |
| TCF12 | transcription factor 12 | -0.01794 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0178145 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0177939 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0177836 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0177739 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0176438 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0176082 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0175887 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0175646 |
