| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.0703852 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0534182 |
| ZNF292 | zinc finger protein 292 | 0.0512589 |
| CENPF | centromere protein F, 350/400kDa | 0.047935 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0431883 |
| RAD51B | RAD51 paralog B | 0.0411469 |
| RIT2 | Ras-like without CAAX 2 | 0.038766 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0327799 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0316407 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0283437 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0275386 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0267644 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0266653 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0263302 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0261 |
| XPO1 | exportin 1 | 0.0259565 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0254723 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0254689 |
| DTNA | dystrobrevin, alpha | 0.0245959 |
| ITGAV | integrin, alpha V | 0.0243995 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0235822 |
| H1-4 | H1.4 linker histone, cluster member | 0.0235239 |
| NCKAP5 | NCK-associated protein 5 | 0.023127 |
| NUP58 | nucleoporin 58 | 0.0230424 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0225178 |
| H1-2 | H1.2 linker histone, cluster member | 0.0225128 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0223692 |
| RTN4 | reticulon 4 | 0.0219496 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0219337 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0218712 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0213021 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0212835 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0210614 |
| RNF145 | ring finger protein 145 | 0.0209829 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0205967 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0203615 |
| CDK8 | cyclin-dependent kinase 8 | 0.0199386 |
| FHIT | fragile histidine triad | 0.0196925 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0196028 |
| CD24 | CD24 molecule | 0.0192086 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0192084 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0190395 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | 0.0188682 |
| NFIA | nuclear factor I/A | 0.0187224 |
| NRXN1 | neurexin 1 | 0.0185064 |
| NBAS | neuroblastoma amplified sequence | 0.0182455 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0181525 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0181311 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0178545 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0178247 |
| CADM1 | cell adhesion molecule 1 | 0.017769 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0176479 |
| LSAMP | limbic system-associated membrane protein | 0.0175977 |
| HLTF | helicase-like transcription factor | 0.0175796 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.017274 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0171035 |
| FAT1 | FAT atypical cadherin 1 | 0.016841 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0167753 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0167569 |
| DST | dystonin | 0.016554 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0165229 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0165029 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0164504 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0163677 |
| AGBL4 | ATP/GTP binding protein-like 4 | 0.0163569 |
| PNN | pinin, desmosome associated protein | 0.0162879 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0162861 |
| PPME1 | protein phosphatase methylesterase 1 | 0.016247 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0161741 |
| MACROD2 | MACRO domain containing 2 | 0.016166 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0161365 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0160639 |
| AHR | aryl hydrocarbon receptor | 0.0159761 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0159406 |
| NGLY1 | N-glycanase 1 | 0.0158404 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0157816 |
| WWOX | WW domain containing oxidoreductase | 0.0157693 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0157121 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0156224 |
| PDS5B | PDS5 cohesin associated factor B | 0.0155692 |
| NLGN1 | neuroligin 1 | 0.0154946 |
| YEATS2 | YEATS domain containing 2 | 0.0154563 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0153519 |
| PCM1 | pericentriolar material 1 | 0.0152798 |
| TXNIP | thioredoxin interacting protein | 0.0152733 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0151877 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0151519 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0150846 |
| ERGIC2 | ERGIC and golgi 2 | 0.0150606 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0150432 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0150028 |
| CHKA | choline kinase alpha | 0.0147944 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.014678 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0146457 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0146375 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0146178 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0145737 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0145523 |
| ZNF326 | zinc finger protein 326 | 0.0144998 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0143627 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.182297 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.100358 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0961147 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0933986 |
| FTL | ferritin, light polypeptide | -0.0871959 |
| VGF | VGF nerve growth factor inducible | -0.0789228 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0783764 |
| ACTG1 | actin gamma 1 | -0.0780415 |
| INHBA | inhibin, beta A | -0.0680359 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0663358 |
| EGR1 | early growth response 1 | -0.0657068 |
| CALCA | calcitonin-related polypeptide alpha | -0.0651652 |
| CNKSR3 | CNKSR family member 3 | -0.0622978 |
| MCL1 | myeloid cell leukemia 1 | -0.0606856 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0590276 |
| RPS3 | ribosomal protein S3 | -0.0572656 |
| STC1 | stanniocalcin 1 | -0.0556496 |
| RPLP1 | ribosomal protein, large, P1 | -0.0554598 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0495024 |
| RPL37A | ribosomal protein L37a | -0.0493188 |
| RPS6 | ribosomal protein S6 | -0.0492744 |
| NBEA | neurobeachin | -0.0491211 |
| RPL8 | ribosomal protein L8 | -0.0486117 |
| ENO1 | enolase 1, (alpha) | -0.0466545 |
| RPS8 | ribosomal protein S8 | -0.0456568 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0455077 |
| CHGA | chromogranin A | -0.0446329 |
| TPM4 | tropomyosin 4 | -0.0440874 |
| COL22A1 | collagen, type XXII, alpha 1 | -0.0429712 |
| PEG10 | paternally expressed 10 | -0.0428892 |
| MT2A | metallothionein 2A | -0.0427208 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0421473 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0409496 |
| RPS21 | ribosomal protein S21 | -0.039582 |
| GNAS | GNAS complex locus | -0.0386252 |
| RPL19 | ribosomal protein L19 | -0.0385141 |
| CANX | calnexin | -0.0384408 |
| FUS | FUS RNA binding protein | -0.0380549 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0372553 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0371227 |
| RPL7 | ribosomal protein L7 | -0.037061 |
| RPS27A | ribosomal protein S27a | -0.0363863 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0356115 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355493 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0349649 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0345347 |
| RPL11 | ribosomal protein L11 | -0.0342295 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0337118 |
| RPL37 | ribosomal protein L37 | -0.0336193 |
| RPL26 | ribosomal protein L26 | -0.0335583 |
| S100A9 | S100 calcium binding protein A9 | -0.0335391 |
| RPS19 | ribosomal protein S19 | -0.0334745 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0329847 |
| UBB | ubiquitin B | -0.0326612 |
| PTCHD4 | patched domain containing 4 | -0.0324788 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0324132 |
| PKM | pyruvate kinase, muscle | -0.0320465 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0319021 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0318863 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0318039 |
| MAP1B | microtubule-associated protein 1B | -0.0317837 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0317582 |
| RPL12 | ribosomal protein L12 | -0.0311869 |
| RPL30 | ribosomal protein L30 | -0.0309868 |
| SVIL | supervillin | -0.030693 |
| RPL23 | ribosomal protein L23 | -0.0306115 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0304594 |
| KIF26B | kinesin family member 26B | -0.0304479 |
| YBX1 | Y box binding protein 1 | -0.0303362 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0303263 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0301596 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.0300901 |
| HOMER1 | homer scaffolding protein 1 | -0.029866 |
| CPE | carboxypeptidase E | -0.029861 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0297699 |
| RPL32 | ribosomal protein L32 | -0.0296179 |
| RPL5 | ribosomal protein L5 | -0.029577 |
| NAV2 | neuron navigator 2 | -0.0293575 |
| RPS16 | ribosomal protein S16 | -0.0293421 |
| NRG1 | neuregulin 1 | -0.0293305 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0291988 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0289485 |
| TMSB10 | thymosin beta 10 | -0.0288062 |
| SETX | senataxin | -0.0288025 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0287901 |
| TXNRD1 | thioredoxin reductase 1 | -0.0285577 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0281069 |
| TMSB4X | thymosin beta 4, X-linked | -0.0280968 |
| RPL35 | ribosomal protein L35 | -0.0278036 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0277371 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0277117 |
| RPS27 | ribosomal protein S27 | -0.0276924 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0276761 |
| ZFHX3 | zinc finger homeobox 3 | -0.0275061 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0274582 |
| GPC6 | glypican 6 | -0.0271995 |
| RPL38 | ribosomal protein L38 | -0.0271203 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0270275 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | -0.0268473 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0267342 |
