| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | 0.0550491 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0543944 |
| MT2A | metallothionein 2A | 0.0521904 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.044412 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0360771 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0311884 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0307367 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0279582 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0268416 |
| NGLY1 | N-glycanase 1 | 0.0265908 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0238438 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0231858 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0225782 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.022158 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0218473 |
| RNF145 | ring finger protein 145 | 0.0214817 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0214333 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0211941 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0200627 |
| MSN | moesin | 0.0197174 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0180726 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.017398 |
| CDK19 | cyclin-dependent kinase 19 | 0.0173013 |
| TMF1 | TATA element modulatory factor 1 | 0.0164675 |
| MMP12 | matrix metallopeptidase 12 | 0.0164371 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.016377 |
| NUP58 | nucleoporin 58 | 0.0163627 |
| TENM1 | teneurin transmembrane protein 1 | 0.0160012 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0157981 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0153151 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0152599 |
| SETD5 | SET domain containing 5 | 0.015257 |
| MT1X | metallothionein 1X | 0.0152331 |
| ZNF292 | zinc finger protein 292 | 0.0150572 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0150509 |
| NDRG1 | N-myc downstream regulated 1 | 0.0149726 |
| ARRDC3 | arrestin domain containing 3 | 0.0149332 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.01489 |
| USP3 | ubiquitin specific peptidase 3 | 0.0147597 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0147164 |
| SPAG9 | sperm associated antigen 9 | 0.014599 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0145356 |
| RPS2 | ribosomal protein S2 | 0.0145262 |
| SEC24A | SEC24 family member A | 0.0137729 |
| VMP1 | vacuole membrane protein 1 | 0.0137442 |
| KLF6 | Kruppel-like factor 6 | 0.0137193 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0136708 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0135938 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.013578 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0130571 |
| RIOK3 | RIO kinase 3 | 0.0130122 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0129694 |
| HELZ | helicase with zinc finger | 0.012865 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0126793 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0126237 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.01241 |
| SMAP1 | small ArfGAP 1 | 0.012309 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0122878 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0122375 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0121782 |
| ATP13A3 | ATPase type 13A3 | 0.012156 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0121389 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0121292 |
| TPM3 | tropomyosin 3 | 0.0120147 |
| SUCO | SUN domain containing ossification factor | 0.0119389 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0117949 |
| CD109 | CD109 molecule | 0.0114291 |
| CEP70 | centrosomal protein 70kDa | 0.011385 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.011305 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0111981 |
| POM121 | POM121 transmembrane nucleoporin | 0.0111416 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0111187 |
| MLF1 | myeloid leukemia factor 1 | 0.0111129 |
| H1-4 | H1.4 linker histone, cluster member | 0.0108726 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0107949 |
| ANXA5 | annexin A5 | 0.0107818 |
| NAV2 | neuron navigator 2 | 0.0107328 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0107247 |
| RLF | rearranged L-myc fusion | 0.0105251 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0104821 |
| GPR137B | G protein-coupled receptor 137B | 0.0104502 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0104394 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0103681 |
| SRP54 | signal recognition particle 54kDa | 0.0103599 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0103352 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0103085 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0102175 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0101983 |
| PRKCI | protein kinase C, iota | 0.0101982 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0101975 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0101903 |
| DENR | density-regulated protein | 0.0101741 |
| OGA | O-GlcNAcase | 0.0101597 |
| RPL21 | ribosomal protein L21 | 0.0101578 |
| CSTB | cystatin B (stefin B) | 0.0101517 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0101459 |
| ZNF654 | zinc finger protein 654 | 0.0100921 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0100583 |
| RPS12 | ribosomal protein S12 | 0.0100518 |
| FBXO42 | F-box protein 42 | 0.0100012 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.262717 |
| FMN1 | formin 1 | -0.23346 |
| NLGN1 | neuroligin 1 | -0.208954 |
| NRG3 | neuregulin 3 | -0.198196 |
| LSAMP | limbic system-associated membrane protein | -0.178968 |
| VIM | vimentin | -0.155787 |
| FRMD4A | FERM domain containing 4A | -0.13538 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0950999 |
| CCND1 | cyclin D1 | -0.084854 |
| PTMA | prothymosin, alpha | -0.0795962 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0720182 |
| FN1 | fibronectin 1 | -0.0701497 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.068125 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0674456 |
| RAD51B | RAD51 paralog B | -0.0662279 |
| DST | dystonin | -0.065255 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0631875 |
| TMSB10 | thymosin beta 10 | -0.0630508 |
| RNF213 | ring finger protein 213 | -0.0596741 |
| ENO1 | enolase 1, (alpha) | -0.0565573 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0552428 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0551538 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0523062 |
| FHIT | fragile histidine triad | -0.0512382 |
| RPL35A | ribosomal protein L35a | -0.0511109 |
| PKM | pyruvate kinase, muscle | -0.0498171 |
| SP100 | SP100 nuclear antigen | -0.0497225 |
| FRMD5 | FERM domain containing 5 | -0.0491902 |
| HDAC9 | histone deacetylase 9 | -0.0490674 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0488939 |
| SFTPA2 | surfactant protein A2 | -0.0486349 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0484518 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0480726 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0466382 |
| HLA-B | major histocompatibility complex, class I, B | -0.0465657 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.045799 |
| PGK1 | phosphoglycerate kinase 1 | -0.0456072 |
| TNNC1 | troponin C type 1 (slow) | -0.0430341 |
| CDK6 | cyclin-dependent kinase 6 | -0.0429917 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.041214 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0392926 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0392366 |
| COMMD10 | COMM domain containing 10 | -0.0391202 |
| PRAME | preferentially expressed antigen in melanoma | -0.0376307 |
| B2M | beta-2-microglobulin | -0.0372678 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0361922 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0359023 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0354172 |
| CBX3 | chromobox homolog 3 | -0.0353878 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0352279 |
| CTTN | cortactin | -0.0337379 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0332964 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0332682 |
| IFI44L | interferon-induced protein 44-like | -0.0330315 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0329753 |
| EHBP1 | EH domain binding protein 1 | -0.0326882 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.032542 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.032297 |
| CTSD | cathepsin D | -0.0315988 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0315827 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0315277 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0312253 |
| RUNX1 | runt-related transcription factor 1 | -0.0310466 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0310156 |
| SQSTM1 | sequestosome 1 | -0.0306227 |
| PLSCR1 | phospholipid scramblase 1 | -0.0302561 |
| EXOC4 | exocyst complex component 4 | -0.0301757 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0300592 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0296667 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0296638 |
| PMEL | premelanosome protein | -0.0295909 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0295209 |
| MSI2 | musashi RNA-binding protein 2 | -0.0292221 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0289085 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0286403 |
| SEPTIN9 | septin 9 | -0.0285435 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0283539 |
| BPTF | bromodomain PHD finger transcription factor | -0.0278218 |
| DIAPH2 | diaphanous-related formin 2 | -0.0275988 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0275659 |
| FOXP1 | forkhead box P1 | -0.0273127 |
| SVIL | supervillin | -0.0268292 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0265909 |
| RPS24 | ribosomal protein S24 | -0.0265741 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0265654 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0264735 |
| RIGI | RNA sensor RIG-I | -0.026465 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0264072 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0263371 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0260571 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0260232 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0259711 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0259419 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0258717 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0258378 |
| HLA-E | major histocompatibility complex, class I, E | -0.0257673 |
| MELTF | melanotransferrin | -0.0256899 |
| CADM1 | cell adhesion molecule 1 | -0.0256545 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0254282 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0253464 |
