Procainamide (hydrochloride)_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Procainamide (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Procainamide (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
GOLGA4 golgin A4 0.107712
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.106661
ADAM10 ADAM metallopeptidase domain 10 0.103972
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.098463
ZEB1 zinc finger E-box binding homeobox 1 0.0939207
TXNIP thioredoxin interacting protein 0.0938904
ZNF292 zinc finger protein 292 0.0915754
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0820589
NAMPT nicotinamide phosphoribosyltransferase 0.0818862
CAMTA1 calmodulin binding transcription activator 1 0.0798735
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.077755
SSBP2 single-stranded DNA binding protein 2 0.0770174
KDM3A lysine (K)-specific demethylase 3A 0.076143
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0752712
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0658283
RBM39 RNA binding motif protein 39 0.0638015
RNF145 ring finger protein 145 0.0637117
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0636904
QKI QKI, KH domain containing, RNA binding 0.0635874
PNISR PNN-interacting serine/arginine-rich protein 0.0633939
FLNB filamin B, beta 0.0622697
EVI5 ecotropic viral integration site 5 0.0616411
PYGB phosphorylase, glycogen; brain 0.0607604
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0599137
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0582206
PTMA prothymosin, alpha 0.0582022
TMSB4X thymosin beta 4, X-linked 0.0578004
RPS2 ribosomal protein S2 0.0570294
NBAS neuroblastoma amplified sequence 0.0569217
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0567714
DSCAM Down syndrome cell adhesion molecule 0.0565888
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0563853
EZR ezrin 0.0557209
VMP1 vacuole membrane protein 1 0.0544526
EML4 echinoderm microtubule associated protein like 4 0.0532239
NFIA nuclear factor I/A 0.050939
SLMAP sarcolemma associated protein 0.0478746
ENO1 enolase 1, (alpha) 0.0476078
SOX6 SRY (sex determining region Y)-box 6 0.0471189
PGK1 phosphoglycerate kinase 1 0.045944
MXI1 MAX interactor 1, dimerization protein 0.0455203
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0454318
JMJD1C jumonji domain containing 1C 0.0441882
EGLN1 egl-9 family hypoxia-inducible factor 1 0.0434078
TPT1 tumor protein, translationally-controlled 1 0.0430511
PDE4B phosphodiesterase 4B, cAMP-specific 0.0427968
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0424786
KMT2E lysine (K)-specific methyltransferase 2E 0.0423716
NAP1L1 nucleosome assembly protein 1-like 1 0.0415242
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0406635
XPO1 exportin 1 0.0401588
KDM6A lysine (K)-specific demethylase 6A 0.0400388
CAMKMT calmodulin-lysine N-methyltransferase 0.0393382
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0387334
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0385946
SET SET nuclear proto-oncogene 0.0385664
FXR1 fragile X mental retardation, autosomal homolog 1 0.0380729
YEATS2 YEATS domain containing 2 0.0380456
RPS8 ribosomal protein S8 0.0379333
CDC73 cell division cycle 73 0.0379317
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0376807
H1-4 H1.4 linker histone, cluster member 0.036812
DENND1A DENN/MADD domain containing 1A 0.0367433
TMF1 TATA element modulatory factor 1 0.0365705
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.0359328
RHOA ras homolog family member A 0.0358008
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0355772
AHNAK AHNAK nucleoprotein 0.0354911
UBA6 ubiquitin-like modifier activating enzyme 6 0.035464
OGA O-GlcNAcase 0.0347901
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0344973
RTN4 reticulon 4 0.0344257
COPB1 coatomer protein complex, subunit beta 1 0.0343959
SBF2 SET binding factor 2 0.0340644
LPP LIM domain containing preferred translocation partner in lipoma 0.0340168
PTBP2 polypyrimidine tract binding protein 2 0.0339449
USP3 ubiquitin specific peptidase 3 0.0337681
TMEM41B transmembrane protein 41B 0.0337005
NCOR1 nuclear receptor corepressor 1 0.0336432
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0336317
BMP2K BMP2 inducible kinase 0.033553
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0335489
WAC WW domain containing adaptor with coiled-coil 0.0335204
MEF2A myocyte enhancer factor 2A 0.0333864
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0333
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.0332038
DIAPH3 diaphanous-related formin 3 0.0331668
RPS12 ribosomal protein S12 0.0329935
FAR1 fatty acyl CoA reductase 1 0.0329747
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.0329074
EFNA5 ephrin-A5 0.0329002
PTK2 protein tyrosine kinase 2 0.0328231
ABHD12 abhydrolase domain containing 12 0.0319945
ELOVL5 ELOVL fatty acid elongase 5 0.0319857
GSK3B glycogen synthase kinase 3 beta 0.0316646
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0312331
PICALM phosphatidylinositol binding clathrin assembly protein 0.0309731
MATR3 matrin 3 0.0308522
ZMYM2 zinc finger, MYM-type 2 0.030698
ELP2 elongator acetyltransferase complex subunit 2 0.0306895

decreased expression

Symbol Name Standardized Value
PKM pyruvate kinase, muscle -0.0885208
EGFR epidermal growth factor receptor -0.0750766
PDE4D phosphodiesterase 4D, cAMP-specific -0.0738417
SLC38A2 solute carrier family 38, member 2 -0.0665022
ENO2 enolase 2 (gamma, neuronal) -0.0427714
PTPRG protein tyrosine phosphatase, receptor type, G -0.0398016
IFI16 interferon, gamma-inducible protein 16 -0.0393133
RPL35A ribosomal protein L35a -0.0373164
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0361605
ZBTB20 zinc finger and BTB domain containing 20 -0.0359454
PRDX2 peroxiredoxin 2 -0.0358221
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0349022
FOXP1 forkhead box P1 -0.0348951
EEF2 eukaryotic translation elongation factor 2 -0.0346898
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0333137
SPRY4 sprouty homolog 4 (Drosophila) -0.0296161
ARHGAP25 Rho GTPase activating protein 25 -0.0296072
ZMYND8 zinc finger, MYND-type containing 8 -0.0294155
PDE7B phosphodiesterase 7B -0.0287345
ACTG1 actin gamma 1 -0.0286248
BPTF bromodomain PHD finger transcription factor -0.0274848
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0272775
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0263271
ATP5F1B ATP synthase F1 subunit beta -0.0253225
GLI3 GLI family zinc finger 3 -0.025269
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0251862
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0243345
LOC112694756 uncharaterized LOC112694756 -0.0242799
PFN1 profilin 1 -0.0231593
POTEF POTE ankyrin domain family, member F -0.0229813
RPL3 ribosomal protein L3 -0.0229763
RPS6 ribosomal protein S6 -0.0228432
YLPM1 YLP motif containing 1 -0.0223974
WARS1 tryptophanyl-tRNA synthetase 1 -0.0223799
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0221256
IRS1 insulin receptor substrate 1 -0.0221247
HEG1 heart development protein with EGF-like domains 1 -0.0220759
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0220124
TXNRD1 thioredoxin reductase 1 -0.0220085
ONECUT2 one cut homeobox 2 -0.0214728
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0214169
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0210833
PRH1 proline-rich protein HaeIII subfamily 1 -0.020896
ZNF438 zinc finger protein 438 -0.0208406
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0205228
CCND1 cyclin D1 -0.0204097
S100A4 S100 calcium binding protein A4 -0.0201535
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0198354
GATAD2A GATA zinc finger domain containing 2A -0.019728
KIF5C kinesin family member 5C -0.0194676
TMSB10 thymosin beta 10 -0.0194384
ETNK1 ethanolamine kinase 1 -0.0193341
HLA-B major histocompatibility complex, class I, B -0.0192831
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0190289
SETX senataxin -0.0187708
FKBP10 FK506 binding protein 10, 65 kDa -0.0185166
EDRF1 erythroid differentiation regulatory factor 1 -0.0184561
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0177629
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0177117
DOCK1 dedicator of cytokinesis 1 -0.0175967
DHFR dihydrofolate reductase -0.0175565
BMP10 bone morphogenetic protein 10 -0.0175348
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.0173387
INTS6 integrator complex subunit 6 -0.0172625
MIPOL1 mirror-image polydactyly 1 -0.0169777
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -0.0168036
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0167704
FER1L6 fer-1-like family member 6 -0.0165777
NCEH1 neutral cholesterol ester hydrolase 1 -0.0164108
PARVA parvin, alpha -0.0164103
BRD4 bromodomain containing 4 -0.0163784
LOC102724023 ES1 protein homolog, mitochondrial -0.0163108
RNASE12 ribonuclease, RNase A family, 12 (non-active) -0.0161352
PRUNE2 prune homolog 2 (Drosophila) -0.0159969
RIGI RNA sensor RIG-I -0.0158871
IARS1 isoleucyl-tRNA synthetase 1 -0.0156785
DPYD dihydropyrimidine dehydrogenase -0.0156723
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0155225
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0154935
PHF14 PHD finger protein 14 -0.0153635
PLSCR1 phospholipid scramblase 1 -0.0150888
ZNHIT6 zinc finger, HIT-type containing 6 -0.0150077
RPS14 ribosomal protein S14 -0.0149033
TMCO3 transmembrane and coiled-coil domains 3 -0.0149029
RHOB ras homolog family member B -0.0148819
LATS2 large tumor suppressor kinase 2 -0.0148577
PIWIL1 piwi-like RNA-mediated gene silencing 1 -0.0148438
ARID5B AT rich interactive domain 5B (MRF1-like) -0.0148376
CORIN corin, serine peptidase -0.0147314
RUNX1 runt-related transcription factor 1 -0.0147134
GCLM glutamate-cysteine ligase, modifier subunit -0.0146793
FAM91A1 family with sequence similarity 91, member A1 -0.0146039
TSC22D1 TSC22 domain family, member 1 -0.0144602
PKP4 plakophilin 4 -0.0144453
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1 -0.0144232
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0142187
CREB5 cAMP responsive element binding protein 5 -0.0140069
RPS11 ribosomal protein S11 -0.0139923
DOCK3 dedicator of cytokinesis 3 -0.0139034
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.0138995