| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.112289 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0990994 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0796006 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0790849 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0624831 |
| MSN | moesin | 0.0538643 |
| ZNF292 | zinc finger protein 292 | 0.0511487 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0495422 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0482691 |
| RTN4 | reticulon 4 | 0.0477068 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0468976 |
| RPS6 | ribosomal protein S6 | 0.0438226 |
| GOLGA4 | golgin A4 | 0.0397683 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0383813 |
| CCNL1 | cyclin L1 | 0.0377545 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0376577 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0374862 |
| MKI67 | marker of proliferation Ki-67 | 0.0373823 |
| POTEF | POTE ankyrin domain family, member F | 0.0367912 |
| PCBP2 | poly(rC) binding protein 2 | 0.0366002 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0365671 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0363278 |
| CENPF | centromere protein F, 350/400kDa | 0.0351944 |
| ATP13A3 | ATPase type 13A3 | 0.0344563 |
| RNF145 | ring finger protein 145 | 0.0330703 |
| RBM39 | RNA binding motif protein 39 | 0.0312398 |
| DSTN | destrin (actin depolymerizing factor) | 0.0301865 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.029775 |
| ARRDC3 | arrestin domain containing 3 | 0.0297247 |
| ANLN | anillin, actin binding protein | 0.0295041 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0284988 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0282381 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0281978 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0281903 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0281177 |
| RPS12 | ribosomal protein S12 | 0.0280073 |
| OGA | O-GlcNAcase | 0.0278706 |
| CRY1 | cryptochrome circadian clock 1 | 0.0268908 |
| MATR3 | matrin 3 | 0.0267879 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0266898 |
| PTMA | prothymosin, alpha | 0.0263675 |
| TXNIP | thioredoxin interacting protein | 0.0262363 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0256883 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0256137 |
| TXNRD1 | thioredoxin reductase 1 | 0.0255047 |
| FOSL1 | FOS-like antigen 1 | 0.0252142 |
| SETD5 | SET domain containing 5 | 0.0250601 |
| XPO1 | exportin 1 | 0.0248684 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0242778 |
| YBX1 | Y box binding protein 1 | 0.0241542 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0235459 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0234545 |
| WDR43 | WD repeat domain 43 | 0.0232969 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0232345 |
| ANXA5 | annexin A5 | 0.0230645 |
| SYAP1 | synapse associated protein 1 | 0.0229939 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0228212 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.02269 |
| RPS2 | ribosomal protein S2 | 0.022504 |
| RLF | rearranged L-myc fusion | 0.0223612 |
| B2M | beta-2-microglobulin | 0.022358 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0223275 |
| QKI | QKI, KH domain containing, RNA binding | 0.0221495 |
| SBF2 | SET binding factor 2 | 0.022112 |
| TFG | TRK-fused gene | 0.0220365 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0219835 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0216864 |
| TMEM41B | transmembrane protein 41B | 0.0214303 |
| SRGN | serglycin | 0.0213417 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0212351 |
| NUP153 | nucleoporin 153kDa | 0.0212082 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0210469 |
| HELZ | helicase with zinc finger | 0.0209823 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0209817 |
| MIS18BP1 | MIS18 binding protein 1 | 0.020636 |
| TBK1 | TANK-binding kinase 1 | 0.0205566 |
| TPX2 | TPX2, microtubule-associated | 0.0203683 |
| DIAPH3 | diaphanous-related formin 3 | 0.0203369 |
| EZR | ezrin | 0.0201426 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0199677 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0199674 |
| SET | SET nuclear proto-oncogene | 0.0198895 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0198508 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0197524 |
| RPL21 | ribosomal protein L21 | 0.0197465 |
| KLF6 | Kruppel-like factor 6 | 0.0195282 |
| RPLP2 | ribosomal protein, large, P2 | 0.0194795 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0185392 |
| ARF4 | ADP-ribosylation factor 4 | 0.0184893 |
| UVRAG | UV radiation resistance associated | 0.0184233 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0183983 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0183559 |
| SPAG9 | sperm associated antigen 9 | 0.0183359 |
| KIF4A | kinesin family member 4A | 0.0183167 |
| HBS1L | HBS1-like translational GTPase | 0.0182937 |
| RPL23 | ribosomal protein L23 | 0.0182081 |
| RASA2 | RAS p21 protein activator 2 | 0.0181459 |
| RBM25 | RNA binding motif protein 25 | 0.0181252 |
| WTAP | Wilms tumor 1 associated protein | 0.0179187 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0178996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.200841 |
| GLIS3 | GLIS family zinc finger 3 | -0.14873 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.146705 |
| HMGA2 | high mobility group AT-hook 2 | -0.126333 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.12396 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.105149 |
| COL6A3 | collagen, type VI, alpha 3 | -0.102264 |
| CDH13 | cadherin 13 | -0.0982266 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0961283 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0947194 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0912834 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0909115 |
| VIM | vimentin | -0.0795311 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.07881 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0781818 |
| PDE10A | phosphodiesterase 10A | -0.0770683 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0716791 |
| HDAC9 | histone deacetylase 9 | -0.0705401 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0694645 |
| INTS6 | integrator complex subunit 6 | -0.0678063 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0678052 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0672263 |
| DST | dystonin | -0.0658982 |
| CD44 | CD44 molecule (Indian blood group) | -0.0644571 |
| KYNU | kynureninase | -0.0643385 |
| VCL | vinculin | -0.0634647 |
| CANX | calnexin | -0.0624788 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.062111 |
| FRMD4A | FERM domain containing 4A | -0.0616044 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0611129 |
| DIAPH2 | diaphanous-related formin 2 | -0.0599328 |
| IER3 | immediate early response 3 | -0.0596092 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0592939 |
| TNS3 | tensin 3 | -0.0585021 |
| HLA-B | major histocompatibility complex, class I, B | -0.0580932 |
| BICC1 | BicC family RNA binding protein 1 | -0.0569339 |
| AHNAK | AHNAK nucleoprotein | -0.056671 |
| EGFR | epidermal growth factor receptor | -0.0565887 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.055739 |
| COL5A1 | collagen, type V, alpha 1 | -0.0553408 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0547126 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0547061 |
| TMEM132D | transmembrane protein 132D | -0.0524898 |
| LDHA | lactate dehydrogenase A | -0.0523061 |
| ATXN1 | ataxin 1 | -0.0515681 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0512259 |
| RAI14 | retinoic acid induced 14 | -0.0508246 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0503766 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0490864 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.047971 |
| FNIP1 | folliculin interacting protein 1 | -0.0479214 |
| HLA-E | major histocompatibility complex, class I, E | -0.0474697 |
| HLA-A | major histocompatibility complex, class I, A | -0.0472409 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0443735 |
| RNF213 | ring finger protein 213 | -0.0439567 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0439238 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0430774 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0425493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0425028 |
| SQSTM1 | sequestosome 1 | -0.0424662 |
| ASPH | aspartate beta-hydroxylase | -0.0421336 |
| VCAN | versican | -0.0411591 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0411073 |
| NAV1 | neuron navigator 1 | -0.0410842 |
| FAM20C | family with sequence similarity 20, member C | -0.0403652 |
| LOX | lysyl oxidase | -0.039685 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0394654 |
| EFNA5 | ephrin-A5 | -0.0383702 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0376581 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0374791 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0373044 |
| NABP1 | nucleic acid binding protein 1 | -0.0373002 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0371318 |
| TMSB4X | thymosin beta 4, X-linked | -0.0365612 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0357235 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.035592 |
| RND3 | Rho family GTPase 3 | -0.035071 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0341267 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0340642 |
| NDRG1 | N-myc downstream regulated 1 | -0.0340414 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0332854 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0332369 |
| SMYD3 | SET and MYND domain containing 3 | -0.0331104 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0326054 |
| PCBP3 | poly(rC) binding protein 3 | -0.0325755 |
| RAD51B | RAD51 paralog B | -0.0322153 |
| PLIN2 | perilipin 2 | -0.0319913 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0317464 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0316033 |
| GOLGB1 | golgin B1 | -0.0314443 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0313479 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0312016 |
| PHF3 | PHD finger protein 3 | -0.0311324 |
| THBS2 | thrombospondin 2 | -0.0306807 |
| INHBA | inhibin, beta A | -0.0304055 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0299303 |
| CTSB | cathepsin B | -0.0298404 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0297972 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0294668 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0293372 |
