| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0812476 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0770616 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0607292 |
| EFNA5 | ephrin-A5 | 0.0558575 |
| PARD3 | par-3 family cell polarity regulator | 0.0529068 |
| SETD5 | SET domain containing 5 | 0.0517179 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0497194 |
| RPS2 | ribosomal protein S2 | 0.0496075 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0488819 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0481345 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0474394 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0466001 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0443533 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0438231 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.042902 |
| PTGES2 | prostaglandin E synthase 2 | 0.0425955 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0414771 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0412414 |
| RAP1A | RAP1A, member of RAS oncogene family | 0.0399941 |
| TPM3 | tropomyosin 3 | 0.0399854 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0396355 |
| VIRMA | vir like m6A methyltransferase associated | 0.0366693 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.036536 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0364707 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0364504 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0357427 |
| RHEB | Ras homolog enriched in brain | 0.035728 |
| RPS8 | ribosomal protein S8 | 0.03563 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.035298 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0351232 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0347905 |
| RPL34 | ribosomal protein L34 | 0.0347542 |
| YEATS2 | YEATS domain containing 2 | 0.0347154 |
| SERINC1 | serine incorporator 1 | 0.0336524 |
| RNF145 | ring finger protein 145 | 0.0335031 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0330527 |
| RNF24 | ring finger protein 24 | 0.0329664 |
| RCOR1 | REST corepressor 1 | 0.0329452 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0327599 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.032512 |
| TMEM165 | transmembrane protein 165 | 0.0323797 |
| RPS3 | ribosomal protein S3 | 0.0317097 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0313603 |
| GOLGB1 | golgin B1 | 0.0312173 |
| RPL9 | ribosomal protein L9 | 0.030826 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0306875 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0302908 |
| SMAD3 | SMAD family member 3 | 0.0296124 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0295129 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0294455 |
| GMPS | guanine monphosphate synthase | 0.0292869 |
| TOP1 | topoisomerase (DNA) I | 0.0288929 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0288926 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0288822 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0288332 |
| SETD2 | SET domain containing 2 | 0.0283704 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 0.0282238 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0280379 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0279832 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0278305 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0275337 |
| HDAC8 | histone deacetylase 8 | 0.0273849 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0273424 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.027261 |
| RORA | RAR-related orphan receptor A | 0.0269244 |
| CDK13 | cyclin-dependent kinase 13 | 0.0269132 |
| MALT1 | MALT1 paracaspase | 0.0268892 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0267423 |
| ACVR1 | activin A receptor, type I | 0.0265987 |
| BRD7 | bromodomain containing 7 | 0.0265617 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0263956 |
| CAB39 | calcium binding protein 39 | 0.0260218 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.025937 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0256878 |
| ADD3 | adducin 3 (gamma) | 0.0256752 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0255285 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | 0.0254274 |
| RPS12 | ribosomal protein S12 | 0.0254047 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0252983 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0252094 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0251454 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0251268 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0250855 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0248695 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0247751 |
| RNF38 | ring finger protein 38 | 0.0247261 |
| HELZ | helicase with zinc finger | 0.0246584 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0246436 |
| NKTR | natural killer cell triggering receptor | 0.0244085 |
| C12ORF75 | chromosome 12 open reading frame 75 | 0.0243106 |
| LAMB1 | laminin, beta 1 | 0.0242466 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0240292 |
| COASY | CoA synthase | 0.0240127 |
| RPL23A | ribosomal protein L23a | 0.023974 |
| RPL21 | ribosomal protein L21 | 0.0237536 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0237337 |
| SMYD3 | SET and MYND domain containing 3 | 0.023707 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.023691 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0236166 |
| TMEM263 | transmembrane protein 263 | 0.0235874 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.247422 |
| COL6A3 | collagen, type VI, alpha 3 | -0.235023 |
| MT2A | metallothionein 2A | -0.19816 |
| HLA-B | major histocompatibility complex, class I, B | -0.163689 |
| TMSB10 | thymosin beta 10 | -0.142766 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.123226 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.110889 |
| MAP1B | microtubule-associated protein 1B | -0.106714 |
| LOX | lysyl oxidase | -0.105721 |
| B2M | beta-2-microglobulin | -0.0992996 |
| VIM | vimentin | -0.0967898 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0896474 |
| SDC4 | syndecan 4 | -0.0873241 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0867959 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0838663 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0829529 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0780469 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0741987 |
| ADM | adrenomedullin | -0.0731058 |
| STC1 | stanniocalcin 1 | -0.0702617 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0700706 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0671132 |
| NRXN3 | neurexin 3 | -0.0635215 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0620774 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0609402 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0583017 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0556488 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0556198 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0542111 |
| ECE1 | endothelin converting enzyme 1 | -0.0541242 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0541094 |
| PKM | pyruvate kinase, muscle | -0.0540528 |
| HLA-C | major histocompatibility complex, class I, C | -0.0538833 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0519579 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0514083 |
| SPAG9 | sperm associated antigen 9 | -0.0513235 |
| POTEF | POTE ankyrin domain family, member F | -0.0509388 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0496183 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0495179 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0495021 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0486079 |
| HIP1 | huntingtin interacting protein 1 | -0.0478039 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0477711 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0467567 |
| CALD1 | caldesmon 1 | -0.0459032 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0458061 |
| RPL11 | ribosomal protein L11 | -0.0456184 |
| UBC | ubiquitin C | -0.0455928 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0451976 |
| NDRG1 | N-myc downstream regulated 1 | -0.0450724 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0447883 |
| QKI | QKI, KH domain containing, RNA binding | -0.0437398 |
| INSIG2 | insulin induced gene 2 | -0.0425577 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0424491 |
| TPM4 | tropomyosin 4 | -0.0420974 |
| CADM1 | cell adhesion molecule 1 | -0.041925 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0411051 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0401339 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.040007 |
| ENO1 | enolase 1, (alpha) | -0.0398923 |
| CYLD | cylindromatosis (turban tumor syndrome) | -0.039478 |
| BSG | basigin (Ok blood group) | -0.0386431 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0381146 |
| ZNF292 | zinc finger protein 292 | -0.0380738 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0378693 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0356257 |
| GPC6 | glypican 6 | -0.035217 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0351938 |
| HDAC9 | histone deacetylase 9 | -0.0346139 |
| TAGLN2 | transgelin 2 | -0.0345155 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0342009 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0341158 |
| WASHC4 | WASH complex subunit 4 | -0.0330414 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0328656 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0327456 |
| CLIC4 | chloride intracellular channel 4 | -0.0322592 |
| CD99 | CD99 molecule | -0.0321627 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0317593 |
| MRTFA | myocardin related transcription factor A | -0.0316634 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0316587 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0314369 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | -0.0314077 |
| CREBBP | CREB binding protein | -0.0312686 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0311699 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0311325 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0310422 |
| MATR3 | matrin 3 | -0.0310335 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0309295 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0307356 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | -0.030677 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0305672 |
| RYBP | RING1 and YY1 binding protein | -0.0304474 |
| YIPF5 | Yip1 domain family, member 5 | -0.0303554 |
| YBX1 | Y box binding protein 1 | -0.0301429 |
| CCNI | cyclin I | -0.0299969 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0298586 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0297187 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.029693 |
| CD44 | CD44 molecule (Indian blood group) | -0.0296818 |
| EGR1 | early growth response 1 | -0.029337 |
