| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.109312 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0796441 |
| SNX14 | sorting nexin 14 | 0.072501 |
| MSN | moesin | 0.0707469 |
| PRELID2 | PRELI domain containing 2 | 0.0703963 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0695439 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0659621 |
| ZNF292 | zinc finger protein 292 | 0.0649327 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0618327 |
| SPAG9 | sperm associated antigen 9 | 0.0573477 |
| CENPF | centromere protein F, 350/400kDa | 0.0557557 |
| NUP58 | nucleoporin 58 | 0.0552859 |
| RNF145 | ring finger protein 145 | 0.0528203 |
| SETD5 | SET domain containing 5 | 0.0525833 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0499297 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0490218 |
| MKI67 | marker of proliferation Ki-67 | 0.0489522 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0477564 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0473272 |
| SET | SET nuclear proto-oncogene | 0.0464672 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0464232 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0455941 |
| TXNRD1 | thioredoxin reductase 1 | 0.0449339 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.044488 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0444667 |
| VMP1 | vacuole membrane protein 1 | 0.0443154 |
| EXOC6B | exocyst complex component 6B | 0.0432767 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0427823 |
| HELZ | helicase with zinc finger | 0.0409153 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0409144 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0407593 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.039518 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0394417 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0391255 |
| PCBP2 | poly(rC) binding protein 2 | 0.0382324 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0375524 |
| SEPTIN2 | septin 2 | 0.0374741 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0373901 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0370076 |
| CCNL1 | cyclin L1 | 0.0369323 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.036432 |
| ATP13A3 | ATPase type 13A3 | 0.0361541 |
| USP37 | ubiquitin specific peptidase 37 | 0.0359119 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0358324 |
| CEP170 | centrosomal protein 170kDa | 0.0355827 |
| TPX2 | TPX2, microtubule-associated | 0.0354151 |
| KIF20B | kinesin family member 20B | 0.0350856 |
| GOLGA4 | golgin A4 | 0.0350593 |
| ANKRD12 | ankyrin repeat domain 12 | 0.03499 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0348428 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0346606 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0344677 |
| DIAPH3 | diaphanous-related formin 3 | 0.0344672 |
| HMGB2 | high mobility group box 2 | 0.033837 |
| HJURP | Holliday junction recognition protein | 0.0338273 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0336526 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0334916 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0333563 |
| RPL11 | ribosomal protein L11 | 0.0330896 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0330437 |
| TUBB | tubulin, beta class I | 0.0329718 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0329018 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.0327145 |
| NBAS | neuroblastoma amplified sequence | 0.0326586 |
| SMAD3 | SMAD family member 3 | 0.0326434 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0325254 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0322916 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0319331 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0316475 |
| UTRN | utrophin | 0.0314035 |
| CCDC91 | coiled-coil domain containing 91 | 0.0313875 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0313549 |
| RACK1 | receptor for activated C kinase 1 | 0.0312552 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0311743 |
| SFXN1 | sideroflexin 1 | 0.0311598 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0308991 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0304532 |
| OLA1 | Obg-like ATPase 1 | 0.0304116 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0303253 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0303065 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0302293 |
| ARRDC3 | arrestin domain containing 3 | 0.0298278 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0294041 |
| CENPE | centromere protein E, 312kDa | 0.0293845 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.0290977 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0290684 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0290023 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0288559 |
| TFG | TRK-fused gene | 0.0288253 |
| ANLN | anillin, actin binding protein | 0.0287569 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0287145 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0285117 |
| CDK19 | cyclin-dependent kinase 19 | 0.0283513 |
| UBAC2 | UBA domain containing 2 | 0.0283363 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0283193 |
| ZNF670 | zinc finger protein 670 | 0.0278381 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0277267 |
| SMYD3 | SET and MYND domain containing 3 | 0.0276886 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0274235 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0273092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.153528 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.113871 |
| PRKCA | protein kinase C, alpha | -0.104377 |
| HMGA2 | high mobility group AT-hook 2 | -0.0949739 |
| LOC112694756 | uncharaterized LOC112694756 | -0.091665 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0874468 |
| LDHA | lactate dehydrogenase A | -0.0821156 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.078274 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0769034 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0755228 |
| INTS6 | integrator complex subunit 6 | -0.0748291 |
| DST | dystonin | -0.0683715 |
| IGF2 | insulin-like growth factor 2 | -0.0682719 |
| VCL | vinculin | -0.0610678 |
| SVIL | supervillin | -0.0577147 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0572001 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0567953 |
| EGR1 | early growth response 1 | -0.0564725 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0529368 |
| PTMA | prothymosin, alpha | -0.051902 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0512138 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0504765 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0504279 |
| EFNA5 | ephrin-A5 | -0.0490779 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0490513 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0490248 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.04846 |
| HDAC9 | histone deacetylase 9 | -0.0476386 |
| AHNAK | AHNAK nucleoprotein | -0.0461417 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0450452 |
| ZNF609 | zinc finger protein 609 | -0.0449423 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0449203 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0447234 |
| VIM | vimentin | -0.0446746 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0446341 |
| ATM | ATM serine/threonine kinase | -0.0438579 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0435181 |
| FMN1 | formin 1 | -0.0429233 |
| PARD3 | par-3 family cell polarity regulator | -0.0426172 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0418665 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0409398 |
| EGFR | epidermal growth factor receptor | -0.0405962 |
| RAI14 | retinoic acid induced 14 | -0.0403958 |
| DENND5B | DENN/MADD domain containing 5B | -0.040261 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0397816 |
| ETV6 | ets variant 6 | -0.0395097 |
| ATG7 | autophagy related 7 | -0.0392472 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0384771 |
| TMEM123 | transmembrane protein 123 | -0.0379015 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0377256 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0375492 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0374336 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0373425 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.037235 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0368767 |
| ATG10 | autophagy related 10 | -0.0363184 |
| FNIP1 | folliculin interacting protein 1 | -0.0362583 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0358079 |
| NLK | nemo-like kinase | -0.0345853 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0345801 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0345502 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0344404 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0343371 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0339538 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0337582 |
| GPC6 | glypican 6 | -0.0337447 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0336252 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0333692 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0331582 |
| TCF12 | transcription factor 12 | -0.0330629 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0329689 |
| TBCA | tubulin folding cofactor A | -0.0329239 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0328811 |
| RAD51B | RAD51 paralog B | -0.0327892 |
| ACTN1 | actinin, alpha 1 | -0.0327475 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0326984 |
| PRSS23 | protease, serine, 23 | -0.0316562 |
| ERBIN | erbb2 interacting protein | -0.0316347 |
| BPTF | bromodomain PHD finger transcription factor | -0.0315505 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0312098 |
| ATXN1 | ataxin 1 | -0.030874 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0307733 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0307281 |
| COL5A1 | collagen, type V, alpha 1 | -0.030591 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.030407 |
| PKM | pyruvate kinase, muscle | -0.0302729 |
| SDC4 | syndecan 4 | -0.0299941 |
| H1-0 | H1.0 linker histone | -0.0297882 |
| PRR16 | proline rich 16 | -0.0297029 |
| GPC5 | glypican 5 | -0.029681 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0294086 |
| SATB2 | SATB homeobox 2 | -0.028994 |
| ACTG1 | actin gamma 1 | -0.0289557 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0288835 |
| TAOK1 | TAO kinase 1 | -0.0288406 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0286584 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0286477 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0285997 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0285691 |
| NALCN | sodium leak channel, non selective | -0.0284642 |
