| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.107713 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0965963 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0915459 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0820425 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0818495 |
| VMP1 | vacuole membrane protein 1 | 0.0791947 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0731187 |
| GLIS3 | GLIS family zinc finger 3 | 0.066496 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0617937 |
| VCL | vinculin | 0.0599149 |
| AHR | aryl hydrocarbon receptor | 0.058516 |
| WDR26 | WD repeat domain 26 | 0.0561968 |
| SMAD3 | SMAD family member 3 | 0.0560296 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0547745 |
| TMEM156 | transmembrane protein 156 | 0.0533481 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0527298 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0519135 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0506944 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0506317 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0503715 |
| OSMR | oncostatin M receptor | 0.0485023 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0483536 |
| INTS6 | integrator complex subunit 6 | 0.0472686 |
| SMYD3 | SET and MYND domain containing 3 | 0.0450927 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0449669 |
| COG5 | component of oligomeric golgi complex 5 | 0.0446038 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0443075 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0429115 |
| ETV6 | ets variant 6 | 0.042703 |
| ADD3 | adducin 3 (gamma) | 0.0425781 |
| ETNK1 | ethanolamine kinase 1 | 0.0423914 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0422126 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0418264 |
| SEPTIN9 | septin 9 | 0.0412881 |
| PTK2 | protein tyrosine kinase 2 | 0.0412244 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0405659 |
| NEK7 | NIMA-related kinase 7 | 0.0401745 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0399415 |
| RUNX1 | runt-related transcription factor 1 | 0.0391475 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0389665 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0387311 |
| GPC6 | glypican 6 | 0.0386575 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0381481 |
| RUNX2 | runt-related transcription factor 2 | 0.0378887 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0370239 |
| PRELID2 | PRELI domain containing 2 | 0.0367149 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0363013 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0356779 |
| WDR43 | WD repeat domain 43 | 0.035316 |
| AEBP2 | AE binding protein 2 | 0.0353042 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0341971 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0330645 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0329177 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0326413 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0325336 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0322023 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0318954 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.031387 |
| CENPF | centromere protein F, 350/400kDa | 0.0313047 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0310113 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0308686 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0306501 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0305574 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0305408 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0302001 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0300826 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0299642 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0298526 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0294971 |
| GSK3B | glycogen synthase kinase 3 beta | 0.029292 |
| SLAIN2 | SLAIN motif family, member 2 | 0.0291891 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.029141 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0290919 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.028938 |
| TMEM165 | transmembrane protein 165 | 0.028893 |
| ETV1 | ets variant 1 | 0.0287764 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0286451 |
| PELO | pelota homolog (Drosophila) | 0.0285102 |
| ASPH | aspartate beta-hydroxylase | 0.0284619 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0284534 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0283914 |
| CAB39 | calcium binding protein 39 | 0.0282561 |
| DENND5B | DENN/MADD domain containing 5B | 0.0280419 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0279163 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0278378 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0277585 |
| SP3 | Sp3 transcription factor | 0.0275778 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0275017 |
| RPL11 | ribosomal protein L11 | 0.027496 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0274717 |
| DST | dystonin | 0.0274653 |
| USP12 | ubiquitin specific peptidase 12 | 0.0274416 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0273367 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0273303 |
| GPHN | gephyrin | 0.02721 |
| SLTM | SAFB-like, transcription modulator | 0.02719 |
| TOP1 | topoisomerase (DNA) I | 0.0271843 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0271437 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0268377 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0268043 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.167582 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.119205 |
| NDRG1 | N-myc downstream regulated 1 | -0.106181 |
| MT2A | metallothionein 2A | -0.0920821 |
| LMNA | lamin A/C | -0.0876063 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0841466 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0794769 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0719278 |
| STC2 | stanniocalcin 2 | -0.067567 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0603372 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.057048 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.054666 |
| TMSB4X | thymosin beta 4, X-linked | -0.0542039 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0536977 |
| PLIN2 | perilipin 2 | -0.0507152 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0495844 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.048319 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0480578 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0474112 |
| FAM13A | family with sequence similarity 13, member A | -0.0464004 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0455318 |
| RAI14 | retinoic acid induced 14 | -0.0448952 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0447417 |
| S100A6 | S100 calcium binding protein A6 | -0.0425576 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0421109 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0413073 |
| EZR | ezrin | -0.0410233 |
| MYOF | myoferlin | -0.0398096 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0386241 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0354594 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.034743 |
| SIRT1 | sirtuin 1 | -0.0343828 |
| DUSP6 | dual specificity phosphatase 6 | -0.0343787 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0336157 |
| ITGA1 | integrin, alpha 1 | -0.0334532 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0326222 |
| UBC | ubiquitin C | -0.030829 |
| CD109 | CD109 molecule | -0.0307414 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0293578 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0291034 |
| EMP1 | epithelial membrane protein 1 | -0.027915 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0271839 |
| WDR45B | WD repeat domain 45B | -0.0263942 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0262129 |
| MYADM | myeloid-associated differentiation marker | -0.0260556 |
| VEGFA | vascular endothelial growth factor A | -0.0259059 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0249109 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.024803 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0246832 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0242519 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.024047 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0239271 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0236041 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0233823 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0229971 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0229778 |
| TCIM | transcriptional and immune response regulator | -0.022956 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0225825 |
| CALR | calreticulin | -0.0224587 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.022288 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0219892 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0219739 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0207757 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0207119 |
| YBX3 | Y box binding protein 3 | -0.0202754 |
| S100A10 | S100 calcium binding protein A10 | -0.0197867 |
| FTL | ferritin, light polypeptide | -0.0196456 |
| FBN1 | fibrillin 1 | -0.0193086 |
| TXNIP | thioredoxin interacting protein | -0.0189598 |
| SPAG9 | sperm associated antigen 9 | -0.018951 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0188476 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0187188 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0185434 |
| MTSS1 | metastasis suppressor 1 | -0.0184565 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0184451 |
| JUN | jun proto-oncogene | -0.0184328 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0183982 |
| RASEF | RAS and EF-hand domain containing | -0.0183783 |
| MT1X | metallothionein 1X | -0.0181556 |
| MMP13 | matrix metallopeptidase 13 | -0.0181067 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.017997 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0178095 |
| NEBL | nebulette | -0.0177066 |
| ZNF395 | zinc finger protein 395 | -0.0175964 |
| TNRC6C | trinucleotide repeat containing 6C | -0.0175512 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0174915 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.0173668 |
| IL6R | interleukin 6 receptor | -0.0173363 |
| IGF2 | insulin-like growth factor 2 | -0.0172047 |
| FOSL1 | FOS-like antigen 1 | -0.0171958 |
| PKM | pyruvate kinase, muscle | -0.0171062 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0168551 |
| IRS2 | insulin receptor substrate 2 | -0.0166546 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0165672 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | -0.0164591 |
| WASF2 | WAS protein family, member 2 | -0.0163484 |
| LAMB3 | laminin, beta 3 | -0.0162935 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.016179 |
| TENM4 | teneurin transmembrane protein 4 | -0.0160848 |
| RAB6A | RAB6A, member RAS oncogene family | -0.016084 |
