| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Procainamide (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0892863 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0542557 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0539372 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0514638 |
| MKI67 | marker of proliferation Ki-67 | 0.0453106 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0445264 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.041845 |
| CENPF | centromere protein F, 350/400kDa | 0.0411545 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.03868 |
| TPX2 | TPX2, microtubule-associated | 0.0367224 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0358918 |
| FTL | ferritin, light polypeptide | 0.0353619 |
| EZR | ezrin | 0.0331246 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0329203 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.032027 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0319889 |
| SNX9 | sorting nexin 9 | 0.0317275 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0312678 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0297644 |
| USP3 | ubiquitin specific peptidase 3 | 0.0280024 |
| PCBP2 | poly(rC) binding protein 2 | 0.0279479 |
| B2M | beta-2-microglobulin | 0.0271632 |
| TXNIP | thioredoxin interacting protein | 0.0269544 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.026912 |
| RNF145 | ring finger protein 145 | 0.0259678 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0256138 |
| MATR3 | matrin 3 | 0.0250321 |
| RIOK3 | RIO kinase 3 | 0.0248978 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0247416 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0235649 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0234852 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0233204 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0231971 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0230602 |
| ZNF292 | zinc finger protein 292 | 0.0227471 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0226488 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0226107 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0217783 |
| DSPP | dentin sialophosphoprotein | 0.021715 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0216659 |
| S100A10 | S100 calcium binding protein A10 | 0.0211101 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0209423 |
| SEPTIN7 | septin 7 | 0.0208556 |
| VMP1 | vacuole membrane protein 1 | 0.020723 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0204931 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0203754 |
| RPS25 | ribosomal protein S25 | 0.0199387 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0195223 |
| FOSL1 | FOS-like antigen 1 | 0.0192071 |
| SGO2 | shugoshin 2 | 0.0190451 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0187991 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0187434 |
| NEK7 | NIMA-related kinase 7 | 0.0186046 |
| MORF4L1 | mortality factor 4 like 1 | 0.0184943 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0182331 |
| PERP | PERP, TP53 apoptosis effector | 0.0179174 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0178895 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0176692 |
| EHF | ets homologous factor | 0.0175619 |
| CDK1 | cyclin-dependent kinase 1 | 0.0174996 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0174222 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.017368 |
| ZFP36 | ZFP36 ring finger protein | 0.0173206 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0172222 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0171395 |
| RPS8 | ribosomal protein S8 | 0.0170876 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0170861 |
| GSTP1 | glutathione S-transferase pi 1 | 0.017 |
| CENPE | centromere protein E, 312kDa | 0.0169733 |
| RPL12 | ribosomal protein L12 | 0.0168481 |
| SET | SET nuclear proto-oncogene | 0.016756 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0165823 |
| KIF4A | kinesin family member 4A | 0.0162432 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0161334 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0161298 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0159916 |
| KIF23 | kinesin family member 23 | 0.0158312 |
| RPS7 | ribosomal protein S7 | 0.0158155 |
| CKAP5 | cytoskeleton associated protein 5 | 0.01574 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0155937 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.015562 |
| DEK | DEK proto-oncogene | 0.0154269 |
| FN1 | fibronectin 1 | 0.0153909 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.015363 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0150285 |
| AREG | amphiregulin | 0.0150197 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0149417 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0148798 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0148747 |
| ANLN | anillin, actin binding protein | 0.0148436 |
| RDX | radixin | 0.0144532 |
| LBR | lamin B receptor | 0.0143915 |
| DSTN | destrin (actin depolymerizing factor) | 0.014357 |
| SERF2 | small EDRK-rich factor 2 | 0.0142889 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0142817 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0142409 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0142368 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.01422 |
| SYAP1 | synapse associated protein 1 | 0.0140077 |
| ENO1 | enolase 1, (alpha) | 0.0139697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.139368 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0861432 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0850803 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0780614 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0775851 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0775563 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0678838 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0670128 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0623552 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0604654 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0595607 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0577677 |
| CDK13 | cyclin-dependent kinase 13 | -0.0561944 |
| NEBL | nebulette | -0.0550091 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0548488 |
| ACTN4 | actinin, alpha 4 | -0.0504336 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0503138 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0497066 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0497021 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0489458 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0469474 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0464986 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0455656 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0454024 |
| BCL2L1 | BCL2-like 1 | -0.0453932 |
| INTS6 | integrator complex subunit 6 | -0.0442749 |
| PLEC | plectin | -0.0441106 |
| EHBP1 | EH domain binding protein 1 | -0.0437787 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0431984 |
| HM13 | histocompatibility (minor) 13 | -0.0427289 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0426991 |
| FLNA | filamin A, alpha | -0.0421542 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0420262 |
| KRT8 | keratin 8, type II | -0.0404192 |
| GOLGB1 | golgin B1 | -0.0400376 |
| GOLGA4 | golgin A4 | -0.0398775 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0392195 |
| APP | amyloid beta (A4) precursor protein | -0.0383366 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0382824 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0382356 |
| VCL | vinculin | -0.0376703 |
| CADPS | Ca++-dependent secretion activator | -0.0370406 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0359905 |
| MYO1E | myosin IE | -0.0357263 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0356685 |
| FAT1 | FAT atypical cadherin 1 | -0.0355655 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0354831 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.035406 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0353212 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0352605 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0346742 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0346316 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0345106 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0343641 |
| CTBP2 | C-terminal binding protein 2 | -0.0342755 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0342163 |
| SVIL | supervillin | -0.03421 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0340442 |
| FAM107B | family with sequence similarity 107, member B | -0.0339737 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0339527 |
| GPHN | gephyrin | -0.033741 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0334835 |
| UBAP2 | ubiquitin associated protein 2 | -0.0328947 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0328343 |
| SMAD3 | SMAD family member 3 | -0.0326731 |
| WWC1 | WW and C2 domain containing 1 | -0.0324953 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0324674 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0324382 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0322554 |
| PKP4 | plakophilin 4 | -0.0315045 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0313659 |
| SRPK2 | SRSF protein kinase 2 | -0.0312556 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0311179 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0310363 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0310185 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0309806 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0308042 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0306398 |
| FRMD5 | FERM domain containing 5 | -0.030188 |
| CMIP | c-Maf inducing protein | -0.0301275 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0301237 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0299668 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0299374 |
| NCOA3 | nuclear receptor coactivator 3 | -0.029397 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0288373 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0286957 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0286686 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0284061 |
| NKTR | natural killer cell triggering receptor | -0.0283643 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0282553 |
| SETX | senataxin | -0.0280125 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0279159 |
| ANXA2 | annexin A2 | -0.0277681 |
| NABP1 | nucleic acid binding protein 1 | -0.0276997 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0273608 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0270141 |
| BBX | bobby sox homolog (Drosophila) | -0.0269111 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0268873 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0268708 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.026791 |
