| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.155271 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.153799 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.110378 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.104337 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0724801 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0718565 |
| ZNF292 | zinc finger protein 292 | 0.0709607 |
| ANLN | anillin, actin binding protein | 0.070839 |
| ENO1 | enolase 1, (alpha) | 0.0689888 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0630499 |
| RPS2 | ribosomal protein S2 | 0.0614409 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0593131 |
| GOLGA4 | golgin A4 | 0.059302 |
| SET | SET nuclear proto-oncogene | 0.0590534 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0588174 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0551418 |
| RPS12 | ribosomal protein S12 | 0.0538469 |
| TXNIP | thioredoxin interacting protein | 0.0529473 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0490819 |
| KIZ | kizuna centrosomal protein | 0.0485518 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0451488 |
| TMF1 | TATA element modulatory factor 1 | 0.0440853 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0438191 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0428063 |
| RPL21 | ribosomal protein L21 | 0.0422968 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0418926 |
| SBF2 | SET binding factor 2 | 0.041236 |
| DSPP | dentin sialophosphoprotein | 0.0411346 |
| H1-2 | H1.2 linker histone, cluster member | 0.0410933 |
| PCBP2 | poly(rC) binding protein 2 | 0.0410693 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0410605 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0407252 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0390638 |
| MSN | moesin | 0.0381868 |
| CENPF | centromere protein F, 350/400kDa | 0.037787 |
| OGA | O-GlcNAcase | 0.0374755 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0374094 |
| MEF2A | myocyte enhancer factor 2A | 0.0366167 |
| RPS6 | ribosomal protein S6 | 0.0360348 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0359405 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0355693 |
| H1-4 | H1.4 linker histone, cluster member | 0.0354862 |
| CD46 | CD46 molecule, complement regulatory protein | 0.034555 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344146 |
| RPS8 | ribosomal protein S8 | 0.0344117 |
| SETD5 | SET domain containing 5 | 0.0334156 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0329767 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0327859 |
| CEP95 | centrosomal protein 95kDa | 0.0324174 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.032366 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0321304 |
| PRRC2C | proline-rich coiled-coil 2C | 0.03169 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0316547 |
| RPL37A | ribosomal protein L37a | 0.0312845 |
| ASPH | aspartate beta-hydroxylase | 0.0312668 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.031093 |
| RPS3 | ribosomal protein S3 | 0.0310045 |
| JMJD1C | jumonji domain containing 1C | 0.0309299 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0307611 |
| RPS7 | ribosomal protein S7 | 0.0307406 |
| SP3 | Sp3 transcription factor | 0.0302449 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0298226 |
| EFNB2 | ephrin-B2 | 0.029764 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0292486 |
| MKI67 | marker of proliferation Ki-67 | 0.0290943 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0287517 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0287086 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0285418 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0285189 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0284502 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0284172 |
| HELZ | helicase with zinc finger | 0.0281556 |
| ARHGAP18 | Rho GTPase activating protein 18 | 0.0280404 |
| YEATS2 | YEATS domain containing 2 | 0.0280348 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0280323 |
| ABHD2 | abhydrolase domain containing 2 | 0.0280291 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0279543 |
| ITGA6 | integrin, alpha 6 | 0.027832 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0277981 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0276485 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0272408 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0269901 |
| FNIP1 | folliculin interacting protein 1 | 0.0269024 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0269021 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0263206 |
| LDHA | lactate dehydrogenase A | 0.0262512 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0259874 |
| PNN | pinin, desmosome associated protein | 0.0258055 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0257383 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.025572 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0255478 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0254153 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0252372 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0251971 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0251885 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0250597 |
| RACK1 | receptor for activated C kinase 1 | 0.0250119 |
| SERINC1 | serine incorporator 1 | 0.0249852 |
| PLIN2 | perilipin 2 | 0.0248564 |
| NAV2 | neuron navigator 2 | 0.0247435 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.276643 |
| EGR1 | early growth response 1 | -0.106945 |
| SLC38A2 | solute carrier family 38, member 2 | -0.104029 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.101027 |
| VCL | vinculin | -0.0829867 |
| TNS3 | tensin 3 | -0.079473 |
| ACTN4 | actinin, alpha 4 | -0.07659 |
| TMSB10 | thymosin beta 10 | -0.0732808 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0727293 |
| SYT1 | synaptotagmin I | -0.0663586 |
| RPL35A | ribosomal protein L35a | -0.0566979 |
| SPATA13 | spermatogenesis associated 13 | -0.051574 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0497401 |
| INTS6 | integrator complex subunit 6 | -0.0487853 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.047211 |
| RPLP1 | ribosomal protein, large, P1 | -0.0471651 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0461263 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0447847 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0440962 |
| BCL2L1 | BCL2-like 1 | -0.0419798 |
| CCND1 | cyclin D1 | -0.0409583 |
| ACTG1 | actin gamma 1 | -0.040796 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0357354 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0351034 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0351013 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0347222 |
| CDK6 | cyclin-dependent kinase 6 | -0.0337463 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0333064 |
| DUSP6 | dual specificity phosphatase 6 | -0.0329668 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0323318 |
| HDAC4 | histone deacetylase 4 | -0.0319692 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0316361 |
| COBL | cordon-bleu WH2 repeat protein | -0.0302721 |
| EZR | ezrin | -0.0298721 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0296374 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0295214 |
| LMO7 | LIM domain 7 | -0.029124 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0285874 |
| JUN | jun proto-oncogene | -0.0275029 |
| YAP1 | Yes-associated protein 1 | -0.026487 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0263531 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0262681 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0262134 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0256727 |
| PKM | pyruvate kinase, muscle | -0.0253616 |
| UBAP2 | ubiquitin associated protein 2 | -0.025285 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0252285 |
| MT2A | metallothionein 2A | -0.0252074 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0251532 |
| CBX3 | chromobox homolog 3 | -0.0250769 |
| TMEM123 | transmembrane protein 123 | -0.0246952 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0242587 |
| ACTN1 | actinin, alpha 1 | -0.0242357 |
| TNS4 | tensin 4 | -0.0240098 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0233206 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0230573 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0228079 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0226323 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0224036 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0222672 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0222399 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0220579 |
| SYNJ2 | synaptojanin 2 | -0.0219242 |
| PKP4 | plakophilin 4 | -0.0215192 |
| TGM2 | transglutaminase 2 | -0.0215002 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0213862 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0213384 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0211057 |
| AFAP1L2 | actin filament associated protein 1-like 2 | -0.0209431 |
| STK24 | serine/threonine kinase 24 | -0.0203853 |
| SEPTIN9 | septin 9 | -0.0197931 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0197193 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0196131 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0195367 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0195059 |
| FOXP1 | forkhead box P1 | -0.0192685 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.0192271 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.01922 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0191313 |
| RPS24 | ribosomal protein S24 | -0.0189294 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0188864 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0187778 |
| NPR2 | natriuretic peptide receptor 2 | -0.018727 |
| MYO1E | myosin IE | -0.0185801 |
| SH3D19 | SH3 domain containing 19 | -0.0185443 |
| AARS1 | alanyl-tRNA synthetase 1 | -0.0183956 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0183126 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0182674 |
| CBFB | core-binding factor, beta subunit | -0.0181748 |
| POTEF | POTE ankyrin domain family, member F | -0.0180845 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.018067 |
| COMMD10 | COMM domain containing 10 | -0.0180627 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0179674 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.017956 |
| MTAP | methylthioadenosine phosphorylase | -0.0179299 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0177796 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0177148 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0176476 |
| PHF14 | PHD finger protein 14 | -0.0175688 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit | -0.0174481 |
