| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Procainamide (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Procainamide (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.174102 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0790847 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0672326 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0637003 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0604824 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0602625 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0536064 |
| GOLGA4 | golgin A4 | 0.0529954 |
| VMP1 | vacuole membrane protein 1 | 0.0447198 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0414059 |
| SPAG9 | sperm associated antigen 9 | 0.0406144 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0404148 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0392521 |
| CLTC | clathrin, heavy chain (Hc) | 0.037239 |
| FNDC3B | fibronectin type III domain containing 3B | 0.036953 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.036225 |
| DUSP10 | dual specificity phosphatase 10 | 0.0345338 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.033365 |
| OGA | O-GlcNAcase | 0.0307661 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0301404 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296054 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0293197 |
| RUNX1 | runt-related transcription factor 1 | 0.0287722 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0285195 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.027277 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0271251 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.026797 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0261324 |
| CENPF | centromere protein F, 350/400kDa | 0.0256367 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0253104 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0253022 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0247323 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0238421 |
| SQSTM1 | sequestosome 1 | 0.0238346 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0236131 |
| NUP58 | nucleoporin 58 | 0.0233693 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0233481 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0224972 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0218703 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0218065 |
| SRGN | serglycin | 0.0216075 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0215451 |
| BBX | bobby sox homolog (Drosophila) | 0.0213856 |
| DIAPH3 | diaphanous-related formin 3 | 0.0213598 |
| KIAA1217 | KIAA1217 | 0.0211365 |
| RNF145 | ring finger protein 145 | 0.0211275 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0209077 |
| COG6 | component of oligomeric golgi complex 6 | 0.0209042 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0208106 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0205774 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0204502 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0200333 |
| PHIP | pleckstrin homology domain interacting protein | 0.0199907 |
| SEC24A | SEC24 family member A | 0.0199617 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0199152 |
| ANXA5 | annexin A5 | 0.0198145 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0192393 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | 0.0188208 |
| RRBP1 | ribosome binding protein 1 | 0.0187684 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0186547 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.0186058 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0182907 |
| CDC27 | cell division cycle 27 | 0.0179792 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.01782 |
| INTS6 | integrator complex subunit 6 | 0.0178194 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.017793 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0176063 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0175915 |
| ENO1 | enolase 1, (alpha) | 0.0175192 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0174926 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0173182 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0171659 |
| ZNF292 | zinc finger protein 292 | 0.0171535 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0168644 |
| SEC23IP | SEC23 interacting protein | 0.0168442 |
| PER1 | period circadian clock 1 | 0.0167415 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0167073 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0166898 |
| CANX | calnexin | 0.0166764 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0166631 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0166251 |
| ZNF451 | zinc finger protein 451 | 0.0165561 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0164887 |
| LDHA | lactate dehydrogenase A | 0.0164817 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0164259 |
| DENND4A | DENN/MADD domain containing 4A | 0.0163881 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0163429 |
| SEPTIN2 | septin 2 | 0.0163261 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0162814 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0162691 |
| WDR43 | WD repeat domain 43 | 0.0161161 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0159709 |
| COPA | coatomer protein complex, subunit alpha | 0.0159488 |
| HELZ | helicase with zinc finger | 0.015857 |
| FAM13A | family with sequence similarity 13, member A | 0.0157279 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0156686 |
| ANLN | anillin, actin binding protein | 0.0156644 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0156544 |
| HDLBP | high density lipoprotein binding protein | 0.0156031 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.0155723 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.229036 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.214099 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.197005 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.186611 |
| INHBA | inhibin, beta A | -0.151474 |
| VIM | vimentin | -0.151394 |
| COL1A1 | collagen, type I, alpha 1 | -0.145642 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.143714 |
| COL6A2 | collagen, type VI, alpha 2 | -0.136759 |
| FN1 | fibronectin 1 | -0.12568 |
| MMP1 | matrix metallopeptidase 1 | -0.125457 |
| MYO10 | myosin X | -0.123485 |
| COL6A1 | collagen, type VI, alpha 1 | -0.111231 |
| OXR1 | oxidation resistance 1 | -0.109162 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.107989 |
| COL1A2 | collagen, type I, alpha 2 | -0.105092 |
| HMGA2 | high mobility group AT-hook 2 | -0.104641 |
| FBN1 | fibrillin 1 | -0.0980044 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0974491 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0899665 |
| EMP1 | epithelial membrane protein 1 | -0.0867812 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0853273 |
| ASPH | aspartate beta-hydroxylase | -0.083225 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0826648 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0791854 |
| TMSB10 | thymosin beta 10 | -0.0790288 |
| HLA-B | major histocompatibility complex, class I, B | -0.0679259 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0655239 |
| CLMP | CXADR-like membrane protein | -0.0637742 |
| CAVIN1 | caveolae associated protein 1 | -0.0608617 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0607998 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0597153 |
| FRMD4A | FERM domain containing 4A | -0.0569787 |
| CDH13 | cadherin 13 | -0.0563942 |
| PRRX1 | paired related homeobox 1 | -0.0553599 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0537193 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0529524 |
| NPTX1 | neuronal pentraxin I | -0.0523225 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0520195 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0470141 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0457547 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0455316 |
| TMEM165 | transmembrane protein 165 | -0.0451362 |
| NAV1 | neuron navigator 1 | -0.0441272 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0440384 |
| DIAPH2 | diaphanous-related formin 2 | -0.0431791 |
| CD44 | CD44 molecule (Indian blood group) | -0.0430827 |
| RAI14 | retinoic acid induced 14 | -0.0424354 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0408106 |
| GLIS3 | GLIS family zinc finger 3 | -0.0400364 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0387222 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0377772 |
| NDRG1 | N-myc downstream regulated 1 | -0.0349035 |
| NCKAP5 | NCK-associated protein 5 | -0.0348936 |
| AHNAK | AHNAK nucleoprotein | -0.0338717 |
| CA12 | carbonic anhydrase XII | -0.033505 |
| COL5A1 | collagen, type V, alpha 1 | -0.0333285 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0330497 |
| CCDC102B | coiled-coil domain containing 102B | -0.0325215 |
| COL5A2 | collagen, type V, alpha 2 | -0.0324775 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0320674 |
| EHBP1 | EH domain binding protein 1 | -0.0319663 |
| MED13L | mediator complex subunit 13-like | -0.0315653 |
| KIAA1549L | KIAA1549-like | -0.0313403 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0311799 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0310054 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0310019 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0308335 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0305503 |
| COL3A1 | collagen, type III, alpha 1 | -0.0304065 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.030364 |
| VCAN | versican | -0.029767 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0297265 |
| ITGA11 | integrin, alpha 11 | -0.0296102 |
| TPM4 | tropomyosin 4 | -0.0295436 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0294121 |
| HLA-A | major histocompatibility complex, class I, A | -0.0293453 |
| NRP1 | neuropilin 1 | -0.0293291 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0291442 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.028402 |
| PRSS23 | protease, serine, 23 | -0.0282972 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0276914 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0272403 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0272291 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0268092 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0267988 |
| RPL35A | ribosomal protein L35a | -0.0267731 |
| EGFR | epidermal growth factor receptor | -0.0266573 |
| CUX1 | cut-like homeobox 1 | -0.0264151 |
| PKM | pyruvate kinase, muscle | -0.0262666 |
| FRMD6 | FERM domain containing 6 | -0.0262323 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0260589 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0260345 |
| PDE8A | phosphodiesterase 8A | -0.0259059 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0251354 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0251197 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0247148 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0246279 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0246211 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0245997 |
