| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0201521 |
| SETD5 | SET domain containing 5 | 0.0162949 |
| GOLGA4 | golgin A4 | 0.0157628 |
| ATP13A3 | ATPase type 13A3 | 0.0152735 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0151129 |
| MMP12 | matrix metallopeptidase 12 | 0.0128448 |
| MYADM | myeloid-associated differentiation marker | 0.0125651 |
| FOSL1 | FOS-like antigen 1 | 0.0122569 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0113767 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.01136 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0110475 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0109998 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0108367 |
| TMF1 | TATA element modulatory factor 1 | 0.0107333 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0102949 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0102879 |
| NGLY1 | N-glycanase 1 | 0.0101356 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0100284 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.00992245 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.00979229 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.00947174 |
| SNX13 | sorting nexin 13 | 0.00943538 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00941384 |
| MSN | moesin | 0.00941143 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.00925509 |
| VMP1 | vacuole membrane protein 1 | 0.00916103 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00905617 |
| RPL21 | ribosomal protein L21 | 0.00886886 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.00882644 |
| TMEM39A | transmembrane protein 39A | 0.00874868 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.00849314 |
| RPS2 | ribosomal protein S2 | 0.00848047 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00836105 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.00833721 |
| LUC7L | LUC7-like (S. cerevisiae) | 0.0082946 |
| HAUS6 | HAUS augmin-like complex, subunit 6 | 0.00828948 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.00823402 |
| GAN | gigaxonin | 0.00814082 |
| RNF145 | ring finger protein 145 | 0.00808205 |
| RCOR1 | REST corepressor 1 | 0.0079975 |
| MEF2A | myocyte enhancer factor 2A | 0.00798989 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.00798608 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.00787705 |
| RND3 | Rho family GTPase 3 | 0.00783003 |
| MICU3 | mitochondrial calcium uptake family, member 3 | 0.00780512 |
| WDR26 | WD repeat domain 26 | 0.00763132 |
| MNT | MAX network transcriptional repressor | 0.00753545 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.00753474 |
| FAM193B | family with sequence similarity 193, member B | 0.00749656 |
| KIAA1328 | KIAA1328 | 0.00747038 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.00741579 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.00740714 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00736672 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.00719295 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.00716279 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.00713714 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00712768 |
| USP37 | ubiquitin specific peptidase 37 | 0.00707982 |
| PAXBP1 | PAX3 and PAX7 binding protein 1 | 0.00705113 |
| SARS1 | seryl-tRNA synthetase 1 | 0.00698217 |
| EXOC1 | exocyst complex component 1 | 0.00691739 |
| SUCO | SUN domain containing ossification factor | 0.00686023 |
| SNX4 | sorting nexin 4 | 0.00685506 |
| OPTN | optineurin | 0.00685309 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00684039 |
| WRN | Werner syndrome, RecQ helicase-like | 0.00683852 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.00682627 |
| CEP70 | centrosomal protein 70kDa | 0.00679726 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00671777 |
| LEMD3 | LEM domain containing 3 | 0.00668428 |
| MARCHF8 | membrane associated ring-CH-type finger 8 | 0.00663266 |
| DENND5A | DENN/MADD domain containing 5A | 0.00662327 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.00659556 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.00659497 |
| ABI1 | abl-interactor 1 | 0.00655748 |
| CD109 | CD109 molecule | 0.00655743 |
| CERT1 | ceramide transporter 1 | 0.00649912 |
| TMEM259 | transmembrane protein 259 | 0.00649335 |
| RAB8B | RAB8B, member RAS oncogene family | 0.00649148 |
| PCGF5 | polycomb group ring finger 5 | 0.0064889 |
| PGM3 | phosphoglucomutase 3 | 0.00646566 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.00644331 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.006429 |
| ZFP36 | ZFP36 ring finger protein | 0.00642107 |
| OXSR1 | oxidative stress responsive 1 | 0.00631572 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0063012 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.00629823 |
| PREPL | prolyl endopeptidase-like | 0.00627161 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.00625035 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.00620479 |
| RYK | receptor-like tyrosine kinase | 0.00617552 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.00613875 |
| NUP153 | nucleoporin 153kDa | 0.00610724 |
| PTEN | phosphatase and tensin homolog | 0.0060919 |
| TRIQK | triple QxxK/R motif containing | 0.00606325 |
| PCBP2 | poly(rC) binding protein 2 | 0.00605402 |
| NCKAP1 | NCK-associated protein 1 | 0.00604999 |
| DTNA | dystrobrevin, alpha | 0.00602679 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.00597719 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00597686 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.23158 |
| TMSB10 | thymosin beta 10 | -0.205171 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.167544 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156061 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146264 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.113269 |
| PODXL | podocalyxin-like | -0.108299 |
| AHNAK | AHNAK nucleoprotein | -0.104264 |
| LOX | lysyl oxidase | -0.103162 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.095052 |
| MT2A | metallothionein 2A | -0.0942679 |
| PLAT | plasminogen activator, tissue | -0.0834042 |
| NDRG1 | N-myc downstream regulated 1 | -0.0830678 |
| CD44 | CD44 molecule (Indian blood group) | -0.0802004 |
| HLA-B | major histocompatibility complex, class I, B | -0.0791856 |
| THBS2 | thrombospondin 2 | -0.0790217 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0776379 |
| NAV1 | neuron navigator 1 | -0.0774319 |
| S100A10 | S100 calcium binding protein A10 | -0.0764277 |
| COL5A1 | collagen, type V, alpha 1 | -0.0763616 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0761148 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0734442 |
| COL3A1 | collagen, type III, alpha 1 | -0.0713492 |
| LOXL2 | lysyl oxidase-like 2 | -0.070277 |
| ANXA2 | annexin A2 | -0.0664796 |
| LMNA | lamin A/C | -0.066429 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0594308 |
| TPM4 | tropomyosin 4 | -0.0588109 |
| COL5A2 | collagen, type V, alpha 2 | -0.058434 |
| B2M | beta-2-microglobulin | -0.0581476 |
| CDH13 | cadherin 13 | -0.0569523 |
| FBN1 | fibrillin 1 | -0.0556909 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0556299 |
| CANX | calnexin | -0.0544508 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0539779 |
| TMSB4X | thymosin beta 4, X-linked | -0.0528859 |
| LOC112694756 | uncharaterized LOC112694756 | -0.052007 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0513711 |
| CALR | calreticulin | -0.0508893 |
| MAP1B | microtubule-associated protein 1B | -0.0499156 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0498926 |
| PKM | pyruvate kinase, muscle | -0.0496631 |
| MX2 | MX dynamin-like GTPase 2 | -0.0495166 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0476585 |
| CAVIN1 | caveolae associated protein 1 | -0.0470097 |
| LDHA | lactate dehydrogenase A | -0.0469835 |
| HLA-C | major histocompatibility complex, class I, C | -0.0463793 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0454616 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0450372 |
| COL1A2 | collagen, type I, alpha 2 | -0.0441418 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0435168 |
| PTMA | prothymosin, alpha | -0.04147 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0414427 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0402266 |
| FSTL1 | follistatin-like 1 | -0.0393394 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0390486 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0381915 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0379127 |
| RNF213 | ring finger protein 213 | -0.037534 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0369367 |
| RIGI | RNA sensor RIG-I | -0.0366961 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0365697 |
| CCND1 | cyclin D1 | -0.0363594 |
| EGFR | epidermal growth factor receptor | -0.0360361 |
| S100A6 | S100 calcium binding protein A6 | -0.0360035 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0356571 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0354882 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0354629 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0351602 |
| ASPH | aspartate beta-hydroxylase | -0.0350224 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0350182 |
| RUNX1 | runt-related transcription factor 1 | -0.0342077 |
| PRSS23 | protease, serine, 23 | -0.0340633 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0338154 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0334881 |
| SP100 | SP100 nuclear antigen | -0.0332739 |
| CTSB | cathepsin B | -0.0323718 |
| ACTG1 | actin gamma 1 | -0.0323692 |
| FN1 | fibronectin 1 | -0.0323623 |
| PGK1 | phosphoglycerate kinase 1 | -0.0322258 |
| APP | amyloid beta (A4) precursor protein | -0.0322041 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0316379 |
| RTN4 | reticulon 4 | -0.0313371 |
| GNAS | GNAS complex locus | -0.0310466 |
| RRBP1 | ribosome binding protein 1 | -0.0302027 |
| ACTN4 | actinin, alpha 4 | -0.0300905 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0298782 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0298626 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0293681 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0293428 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0289771 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0288173 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0287226 |
| FLNA | filamin A, alpha | -0.0286482 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0284803 |
| RPL35A | ribosomal protein L35a | -0.0284437 |
| FLNB | filamin B, beta | -0.0283648 |
| PARD3 | par-3 family cell polarity regulator | -0.0280282 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0279772 |
| SFTPA2 | surfactant protein A2 | -0.0276374 |
