| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.0784788 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0673095 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0656161 |
| GOLGA4 | golgin A4 | 0.0585538 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0580516 |
| ATP13A3 | ATPase type 13A3 | 0.0513115 |
| VMP1 | vacuole membrane protein 1 | 0.0488762 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0396266 |
| TMF1 | TATA element modulatory factor 1 | 0.0385271 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0356617 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0347418 |
| MT2A | metallothionein 2A | 0.0300986 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.029693 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0292319 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0291305 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0290582 |
| RASA2 | RAS p21 protein activator 2 | 0.0287371 |
| ANKRD12 | ankyrin repeat domain 12 | 0.028258 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0276289 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0271845 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0267925 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0255509 |
| TMEM165 | transmembrane protein 165 | 0.0247654 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0247271 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0241184 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0236304 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0230264 |
| TMEM41B | transmembrane protein 41B | 0.0226146 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0220769 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0218723 |
| NKTR | natural killer cell triggering receptor | 0.0214416 |
| SETD5 | SET domain containing 5 | 0.0212894 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0212563 |
| ERBIN | erbb2 interacting protein | 0.0212194 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0204146 |
| VIM | vimentin | 0.0204136 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0201045 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.0199283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0198375 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0196111 |
| CEP95 | centrosomal protein 95kDa | 0.0192563 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0188595 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0188181 |
| KLHDC10 | kelch domain containing 10 | 0.0186257 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0185325 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0182222 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0177138 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.017648 |
| SBF2 | SET binding factor 2 | 0.0175866 |
| NGLY1 | N-glycanase 1 | 0.0171888 |
| NAV2 | neuron navigator 2 | 0.0171345 |
| GOLGA2 | golgin A2 | 0.0171119 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0169927 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.016951 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0167286 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.016426 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0163083 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0160748 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0160039 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0159588 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0157924 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0157475 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0156743 |
| FAM107B | family with sequence similarity 107, member B | 0.0154902 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0153888 |
| KIF1B | kinesin family member 1B | 0.0153256 |
| RHOA | ras homolog family member A | 0.015178 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0150994 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0149287 |
| CD109 | CD109 molecule | 0.014707 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0146163 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0146161 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0145845 |
| NCK1 | NCK adaptor protein 1 | 0.0144947 |
| DUSP6 | dual specificity phosphatase 6 | 0.0144183 |
| SPAG9 | sperm associated antigen 9 | 0.0141292 |
| INTS10 | integrator complex subunit 10 | 0.0140132 |
| SQLE | squalene epoxidase | 0.0139939 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0139351 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0138764 |
| CLMP | CXADR-like membrane protein | 0.013876 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0138666 |
| PKN2 | protein kinase N2 | 0.0138335 |
| CA5B | carbonic anhydrase VB, mitochondrial | 0.0138332 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0138166 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.013682 |
| KLF6 | Kruppel-like factor 6 | 0.0136288 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0136094 |
| RARS2 | arginyl-tRNA synthetase 2, mitochondrial | 0.0135978 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0133077 |
| USP36 | ubiquitin specific peptidase 36 | 0.0130325 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0129645 |
| SNX14 | sorting nexin 14 | 0.0128285 |
| ZNF654 | zinc finger protein 654 | 0.0128188 |
| MTDH | metadherin | 0.0127197 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0127194 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0125686 |
| CDC27 | cell division cycle 27 | 0.0125605 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0125524 |
| VEGFA | vascular endothelial growth factor A | 0.0125291 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.384192 |
| COL6A3 | collagen, type VI, alpha 3 | -0.271733 |
| CDH13 | cadherin 13 | -0.113141 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.10622 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0982297 |
| NDRG1 | N-myc downstream regulated 1 | -0.0970393 |
| COL1A1 | collagen, type I, alpha 1 | -0.0966406 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0942046 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0908804 |
| COL5A1 | collagen, type V, alpha 1 | -0.0888423 |
| CADM1 | cell adhesion molecule 1 | -0.0868361 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0757437 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0743065 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0681201 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0656146 |
| FBN1 | fibrillin 1 | -0.0646476 |
| COL1A2 | collagen, type I, alpha 2 | -0.0636593 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0632242 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0569396 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0551915 |
| TPM4 | tropomyosin 4 | -0.0541194 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0513023 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0509926 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0502608 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0488961 |
| ASPH | aspartate beta-hydroxylase | -0.0478679 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0471765 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0460473 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0451124 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0450115 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0445839 |
| VCAN | versican | -0.0442673 |
| CLIC4 | chloride intracellular channel 4 | -0.0442525 |
| CALR | calreticulin | -0.0441797 |
| CALD1 | caldesmon 1 | -0.0436967 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0436337 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.042404 |
| PKM | pyruvate kinase, muscle | -0.0423905 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0422039 |
| CD44 | CD44 molecule (Indian blood group) | -0.0400066 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0399662 |
| PRELID2 | PRELI domain containing 2 | -0.0396838 |
| COL7A1 | collagen, type VII, alpha 1 | -0.039157 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0388759 |
| EGFR | epidermal growth factor receptor | -0.0383366 |
| POSTN | periostin, osteoblast specific factor | -0.0381229 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0371167 |
| FLNA | filamin A, alpha | -0.0360924 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0355854 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0355731 |
| IL6ST | interleukin 6 signal transducer | -0.0350999 |
| AHNAK | AHNAK nucleoprotein | -0.0350479 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0344029 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0342399 |
| CNTN5 | contactin 5 | -0.0341813 |
| PLEC | plectin | -0.033757 |
| RUNX1 | runt-related transcription factor 1 | -0.0333544 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0331052 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0319714 |
| GLIS3 | GLIS family zinc finger 3 | -0.0313609 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0312767 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.030818 |
| TMSB4X | thymosin beta 4, X-linked | -0.0304684 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0304557 |
| CANX | calnexin | -0.0295364 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.02912 |
| IER3 | immediate early response 3 | -0.0290763 |
| ACTG1 | actin gamma 1 | -0.0289684 |
| IL6 | interleukin 6 | -0.0287218 |
| RIGI | RNA sensor RIG-I | -0.0284808 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0279096 |
| FAT1 | FAT atypical cadherin 1 | -0.0275208 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0270325 |
| TPM1 | tropomyosin 1 (alpha) | -0.0267122 |
| GRB10 | growth factor receptor-bound protein 10 | -0.026658 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0263491 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0263444 |
| SQSTM1 | sequestosome 1 | -0.0260229 |
| APP | amyloid beta (A4) precursor protein | -0.0258285 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0247726 |
| EXOC4 | exocyst complex component 4 | -0.0246785 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0243424 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0241381 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0236791 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0236572 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0235638 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0233462 |
| EXT1 | exostosin glycosyltransferase 1 | -0.023317 |
| COL3A1 | collagen, type III, alpha 1 | -0.0230277 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0229991 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0229945 |
| PGK1 | phosphoglycerate kinase 1 | -0.0229362 |
| DST | dystonin | -0.0225138 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0219457 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0213932 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0213482 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0213359 |
| POTEF | POTE ankyrin domain family, member F | -0.0213054 |
| STC2 | stanniocalcin 2 | -0.0212588 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0208761 |
