| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.134616 |
| NDRG1 | N-myc downstream regulated 1 | 0.1066 |
| FAM13A | family with sequence similarity 13, member A | 0.0894752 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0856583 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0851276 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0801383 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0606539 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0606167 |
| VEGFA | vascular endothelial growth factor A | 0.0581287 |
| FLNB | filamin B, beta | 0.0558596 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0543062 |
| VMP1 | vacuole membrane protein 1 | 0.0540843 |
| CALB1 | calbindin 1, 28kDa | 0.0477173 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0458552 |
| PTEN | phosphatase and tensin homolog | 0.04482 |
| CCNY | cyclin Y | 0.0379025 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0378493 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0365667 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0342373 |
| CDK19 | cyclin-dependent kinase 19 | 0.0329916 |
| PRELID2 | PRELI domain containing 2 | 0.0327943 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0323114 |
| EXOC1 | exocyst complex component 1 | 0.0298814 |
| LIMA1 | LIM domain and actin binding 1 | 0.0294539 |
| TNS4 | tensin 4 | 0.0292136 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0287513 |
| ABHD2 | abhydrolase domain containing 2 | 0.0284702 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0282695 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0278079 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0274995 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0274968 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0271485 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0270745 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0270736 |
| SUCO | SUN domain containing ossification factor | 0.0269449 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0265908 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0255897 |
| MXD1 | MAX dimerization protein 1 | 0.0253879 |
| SETD5 | SET domain containing 5 | 0.0253715 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0249608 |
| RPL21 | ribosomal protein L21 | 0.0247233 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0236771 |
| ZFP36 | ZFP36 ring finger protein | 0.0231608 |
| CCDC186 | coiled-coil domain containing 186 | 0.0228637 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0227007 |
| CD47 | CD47 molecule | 0.022328 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0223111 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0222093 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0221823 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0220686 |
| ENO1 | enolase 1, (alpha) | 0.0214324 |
| ADD3 | adducin 3 (gamma) | 0.021257 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0210015 |
| RNF149 | ring finger protein 149 | 0.0207681 |
| ATP11B | ATPase, class VI, type 11B | 0.0206284 |
| GOLGA4 | golgin A4 | 0.0204618 |
| PLAUR | plasminogen activator, urokinase receptor | 0.020458 |
| DSPP | dentin sialophosphoprotein | 0.0203942 |
| ZNF292 | zinc finger protein 292 | 0.0203486 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0200983 |
| SLK | STE20-like kinase | 0.0200609 |
| KAZN | kazrin, periplakin interacting protein | 0.0199792 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0196848 |
| ZNF638 | zinc finger protein 638 | 0.0196325 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0196055 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0195588 |
| PCBP2 | poly(rC) binding protein 2 | 0.019337 |
| SBF2 | SET binding factor 2 | 0.0191245 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0191232 |
| CENPF | centromere protein F, 350/400kDa | 0.0188874 |
| CDCP1 | CUB domain containing protein 1 | 0.0188828 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0188399 |
| RNF217 | ring finger protein 217 | 0.0186432 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0185794 |
| FNBP1L | formin binding protein 1-like | 0.0184288 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0182772 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0182344 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0181837 |
| CLDN7 | claudin 7 | 0.0181823 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0180968 |
| FOSL1 | FOS-like antigen 1 | 0.0180259 |
| N4BP1 | NEDD4 binding protein 1 | 0.0179976 |
| PRSS3 | protease, serine, 3 | 0.0177329 |
| SCFD1 | sec1 family domain containing 1 | 0.0176094 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.017587 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0175837 |
| INSIG1 | insulin induced gene 1 | 0.0175639 |
| TMF1 | TATA element modulatory factor 1 | 0.0175425 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.017476 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0174622 |
| COG6 | component of oligomeric golgi complex 6 | 0.017449 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0171778 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0171724 |
| PTCH1 | patched 1 | 0.0170635 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.016925 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0168951 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0166732 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0166395 |
| NBAS | neuroblastoma amplified sequence | 0.0165193 |
| NUCB2 | nucleobindin 2 | 0.0164044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.251629 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.11265 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.089005 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0856251 |
| TMSB10 | thymosin beta 10 | -0.0849349 |
| PTMA | prothymosin, alpha | -0.0813659 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0775098 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0730929 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0713852 |
| ONECUT3 | one cut homeobox 3 | -0.0707052 |
| ACTN4 | actinin, alpha 4 | -0.0691688 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0650023 |
| MYO1E | myosin IE | -0.0633439 |
| RBM39 | RNA binding motif protein 39 | -0.0606903 |
| KRT8 | keratin 8, type II | -0.0600957 |
| VCL | vinculin | -0.055759 |
| AHNAK | AHNAK nucleoprotein | -0.0553153 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0552202 |
| ACTG1 | actin gamma 1 | -0.0549719 |
| KRT18 | keratin 18, type I | -0.0544178 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0541062 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0533394 |
| PIGR | polymeric immunoglobulin receptor | -0.0523124 |
| LMO7 | LIM domain 7 | -0.0510822 |
| CCND1 | cyclin D1 | -0.0507938 |
| CD44 | CD44 molecule (Indian blood group) | -0.0500142 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0492204 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0483452 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0482064 |
| H1-0 | H1.0 linker histone | -0.0480789 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0446387 |
| RPS24 | ribosomal protein S24 | -0.0444216 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0440776 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0425636 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0417943 |
| RPLP1 | ribosomal protein, large, P1 | -0.0404612 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0403266 |
| ARF1 | ADP-ribosylation factor 1 | -0.0397868 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0392854 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0390015 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0389747 |
| TFRC | transferrin receptor | -0.0385189 |
| RPL34 | ribosomal protein L34 | -0.0380894 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0374923 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0373269 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0371334 |
| LMNA | lamin A/C | -0.0369433 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0368042 |
| GPHN | gephyrin | -0.03626 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0359364 |
| RPS8 | ribosomal protein S8 | -0.0358452 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.035735 |
| HDLBP | high density lipoprotein binding protein | -0.0356389 |
| ANXA2 | annexin A2 | -0.0352702 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0346276 |
| APP | amyloid beta (A4) precursor protein | -0.0342966 |
| IER3 | immediate early response 3 | -0.0340087 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0339308 |
| RACK1 | receptor for activated C kinase 1 | -0.0337379 |
| MYOF | myoferlin | -0.0332585 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0331827 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0329222 |
| CUX1 | cut-like homeobox 1 | -0.0328481 |
| NOP58 | NOP58 ribonucleoprotein | -0.0327563 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0326054 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0325693 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0325473 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.032022 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0319462 |
| CADPS | Ca++-dependent secretion activator | -0.0318579 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0315581 |
| HDAC2 | histone deacetylase 2 | -0.0312061 |
| FOXO1 | forkhead box O1 | -0.0311216 |
| CTBP2 | C-terminal binding protein 2 | -0.0308645 |
| CANX | calnexin | -0.0308314 |
| GDF15 | growth differentiation factor 15 | -0.030826 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0305535 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0305135 |
| TXNRD1 | thioredoxin reductase 1 | -0.0304933 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0300857 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.029958 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0299299 |
| EPCAM | epithelial cell adhesion molecule | -0.0298508 |
| RPL13A | ribosomal protein L13a | -0.0296122 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0293975 |
| SMYD3 | SET and MYND domain containing 3 | -0.029296 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0292727 |
| POF1B | premature ovarian failure, 1B | -0.0291614 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.029117 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.029015 |
| MTAP | methylthioadenosine phosphorylase | -0.0289331 |
| RPL4 | ribosomal protein L4 | -0.0289305 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0287736 |
| FUS | FUS RNA binding protein | -0.0287423 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0286866 |
| RPL26 | ribosomal protein L26 | -0.0281956 |
| RBM25 | RNA binding motif protein 25 | -0.0280804 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0280144 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0277677 |
| ANXA1 | annexin A1 | -0.0277219 |
