| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.0637349 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0625668 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0613528 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0596583 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0433799 |
| CENPF | centromere protein F, 350/400kDa | 0.0408875 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0395644 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0391625 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0350615 |
| CDK19 | cyclin-dependent kinase 19 | 0.0350128 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0343657 |
| MSN | moesin | 0.0343335 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0341331 |
| VMP1 | vacuole membrane protein 1 | 0.0335435 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0333178 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0331246 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0316993 |
| MEF2A | myocyte enhancer factor 2A | 0.031622 |
| CAPRIN2 | caprin family member 2 | 0.031558 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0291355 |
| MYADM | myeloid-associated differentiation marker | 0.0290484 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0270762 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0264626 |
| SETD5 | SET domain containing 5 | 0.0262729 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.026171 |
| SLK | STE20-like kinase | 0.0261377 |
| PLIN2 | perilipin 2 | 0.0258983 |
| RAI1 | retinoic acid induced 1 | 0.0252216 |
| FOSL1 | FOS-like antigen 1 | 0.0244966 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0240754 |
| RPS12 | ribosomal protein S12 | 0.0236993 |
| VEGFA | vascular endothelial growth factor A | 0.0235444 |
| NGLY1 | N-glycanase 1 | 0.0234272 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0232875 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0231247 |
| POTEF | POTE ankyrin domain family, member F | 0.022811 |
| PCBP2 | poly(rC) binding protein 2 | 0.022487 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0222108 |
| TMEM41B | transmembrane protein 41B | 0.0220324 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0219125 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0216769 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0214156 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0213591 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0210263 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0205742 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0201582 |
| ANGPTL4 | angiopoietin-like 4 | 0.020028 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.019981 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0198312 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0196053 |
| FNIP1 | folliculin interacting protein 1 | 0.0195889 |
| MKI67 | marker of proliferation Ki-67 | 0.0195023 |
| EFNA5 | ephrin-A5 | 0.0194315 |
| WASF2 | WAS protein family, member 2 | 0.0192936 |
| YEATS2 | YEATS domain containing 2 | 0.0191865 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0187297 |
| ARRDC3 | arrestin domain containing 3 | 0.0186552 |
| EGR1 | early growth response 1 | 0.0185493 |
| SET | SET nuclear proto-oncogene | 0.0185305 |
| KLHL24 | kelch-like family member 24 | 0.0185149 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0180696 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0180388 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0178984 |
| RPS6 | ribosomal protein S6 | 0.0178424 |
| HJURP | Holliday junction recognition protein | 0.0177724 |
| RPL21 | ribosomal protein L21 | 0.0176733 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0176162 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0174823 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0173913 |
| HMGA1 | high mobility group AT-hook 1 | 0.0172943 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0172506 |
| TMF1 | TATA element modulatory factor 1 | 0.0170025 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0166821 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.016571 |
| PGM3 | phosphoglucomutase 3 | 0.0165682 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0164392 |
| CD109 | CD109 molecule | 0.0163891 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0161779 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0161058 |
| NPHP3 | nephronophthisis 3 (adolescent) | 0.0160388 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0159495 |
| RPS23 | ribosomal protein S23 | 0.0158364 |
| NDRG1 | N-myc downstream regulated 1 | 0.0155504 |
| GOLGB1 | golgin B1 | 0.0153751 |
| CFAP96 | cilia and flagella associated protein 96 | 0.0152987 |
| PHF3 | PHD finger protein 3 | 0.0151365 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0151024 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0150876 |
| ZFP36 | ZFP36 ring finger protein | 0.0148363 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0148161 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0148069 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0145039 |
| OPTN | optineurin | 0.0144867 |
| HDGF | hepatoma-derived growth factor | 0.014466 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0144155 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0143328 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0142395 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0141765 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.0141248 |
| SNX14 | sorting nexin 14 | 0.0140003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.252617 |
| CD44 | CD44 molecule (Indian blood group) | -0.184258 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.138511 |
| TMSB4X | thymosin beta 4, X-linked | -0.128161 |
| TP63 | tumor protein p63 | -0.120453 |
| TMSB10 | thymosin beta 10 | -0.118501 |
| TXNRD1 | thioredoxin reductase 1 | -0.114171 |
| DST | dystonin | -0.0934316 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0889359 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0875995 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0874618 |
| APP | amyloid beta (A4) precursor protein | -0.0843252 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0811566 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0803056 |
| RUNX1 | runt-related transcription factor 1 | -0.0780789 |
| AHNAK | AHNAK nucleoprotein | -0.0688344 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0662369 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0641187 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0632932 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0631196 |
| VIM | vimentin | -0.0606803 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0594631 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0594563 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0589657 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0589335 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0587419 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0586612 |
| SPAG9 | sperm associated antigen 9 | -0.0577521 |
| FMNL2 | formin-like 2 | -0.0569754 |
| RIGI | RNA sensor RIG-I | -0.0565827 |
| SP100 | SP100 nuclear antigen | -0.0562649 |
| ACTG1 | actin gamma 1 | -0.0560356 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0558002 |
| CADM2 | cell adhesion molecule 2 | -0.0555918 |
| CMIP | c-Maf inducing protein | -0.0544567 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0533682 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0529036 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0528483 |
| RNF213 | ring finger protein 213 | -0.0517346 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0516978 |
| RGS4 | regulator of G-protein signaling 4 | -0.0514712 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0514632 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0501604 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0495052 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0494468 |
| CFAP299 | cilia and flagella associated protein 299 | -0.046925 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0465696 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0462603 |
| FUS | FUS RNA binding protein | -0.0461572 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0453965 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0444353 |
| RBM39 | RNA binding motif protein 39 | -0.0444065 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0443483 |
| LDHA | lactate dehydrogenase A | -0.0433654 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.043286 |
| PGK1 | phosphoglycerate kinase 1 | -0.0415714 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0413132 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0408805 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0408314 |
| PLSCR1 | phospholipid scramblase 1 | -0.0408184 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0403688 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0396251 |
| OLA1 | Obg-like ATPase 1 | -0.0394596 |
| ZNF217 | zinc finger protein 217 | -0.0392424 |
| RPL4 | ribosomal protein L4 | -0.0391089 |
| TMEM123 | transmembrane protein 123 | -0.0391022 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0390987 |
| CDK6 | cyclin-dependent kinase 6 | -0.0380106 |
| ARF1 | ADP-ribosylation factor 1 | -0.0379541 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0376352 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0376025 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0375023 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0371006 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0363643 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0361494 |
| SMAD3 | SMAD family member 3 | -0.035698 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0353971 |
| TFRC | transferrin receptor | -0.035317 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0348439 |
| WDR45B | WD repeat domain 45B | -0.0346102 |
| EMP1 | epithelial membrane protein 1 | -0.0345049 |
| EPHA4 | EPH receptor A4 | -0.0343535 |
| HDLBP | high density lipoprotein binding protein | -0.0341142 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0327344 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0321385 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0320921 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.031909 |
| PDE10A | phosphodiesterase 10A | -0.0318867 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0318208 |
| AFF4 | AF4/FMR2 family, member 4 | -0.031782 |
| USP34 | ubiquitin specific peptidase 34 | -0.0315512 |
| EZR | ezrin | -0.0314704 |
| YBX1 | Y box binding protein 1 | -0.0313889 |
| VCL | vinculin | -0.0310389 |
| SMYD3 | SET and MYND domain containing 3 | -0.030899 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0308545 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0307223 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0307053 |
| NF1 | neurofibromin 1 | -0.0302463 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0298499 |
