| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.209245 |
| FAM13A | family with sequence similarity 13, member A | 0.110247 |
| MT2A | metallothionein 2A | 0.0828512 |
| LAMC2 | laminin, gamma 2 | 0.0756614 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0724366 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0646626 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0625772 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0614831 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0584672 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0581985 |
| STC1 | stanniocalcin 1 | 0.0577066 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0554418 |
| MCL1 | myeloid cell leukemia 1 | 0.0536853 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0502866 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0501172 |
| ENO1 | enolase 1, (alpha) | 0.0496867 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0462936 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0455914 |
| NGLY1 | N-glycanase 1 | 0.0454353 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0454235 |
| MKI67 | marker of proliferation Ki-67 | 0.0451978 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0450591 |
| VMP1 | vacuole membrane protein 1 | 0.0439721 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0439325 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0429323 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0420196 |
| SLTM | SAFB-like, transcription modulator | 0.0413331 |
| SPAG9 | sperm associated antigen 9 | 0.0408424 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0392885 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0390007 |
| DSPP | dentin sialophosphoprotein | 0.0389826 |
| PTMA | prothymosin, alpha | 0.0377899 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0365265 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0364595 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0353821 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.034488 |
| ARRDC3 | arrestin domain containing 3 | 0.0344392 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0328096 |
| RPS12 | ribosomal protein S12 | 0.0326524 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0325539 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0317238 |
| RPS3 | ribosomal protein S3 | 0.031385 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0308331 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0305288 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0303407 |
| CSTB | cystatin B (stefin B) | 0.0301319 |
| GOLGA4 | golgin A4 | 0.0300867 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0298561 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0297139 |
| PYGL | phosphorylase, glycogen, liver | 0.0296235 |
| SEC61G | Sec61 gamma subunit | 0.0295585 |
| RASA2 | RAS p21 protein activator 2 | 0.0293981 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0290358 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0287493 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0284174 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0282387 |
| ZNF292 | zinc finger protein 292 | 0.0281197 |
| RPL37A | ribosomal protein L37a | 0.0280713 |
| B2M | beta-2-microglobulin | 0.0278488 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0274187 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.026909 |
| RPS6 | ribosomal protein S6 | 0.0268919 |
| SEPTIN2 | septin 2 | 0.0264228 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0263894 |
| RPS25 | ribosomal protein S25 | 0.0263155 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0260456 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0254541 |
| SQSTM1 | sequestosome 1 | 0.0252937 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0251197 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0245539 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0245351 |
| RPS2 | ribosomal protein S2 | 0.0244234 |
| TMF1 | TATA element modulatory factor 1 | 0.0243534 |
| PGK1 | phosphoglycerate kinase 1 | 0.0243391 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0242821 |
| FRY | furry homolog (Drosophila) | 0.0242273 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0240073 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0238896 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0238693 |
| RPS8 | ribosomal protein S8 | 0.0238064 |
| LAMB3 | laminin, beta 3 | 0.0234305 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0231098 |
| ENSA | endosulfine alpha | 0.0230221 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0229484 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0229229 |
| LAMA4 | laminin, alpha 4 | 0.0226859 |
| MYO1E | myosin IE | 0.0225417 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0223516 |
| AREG | amphiregulin | 0.0221315 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.022 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0219824 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0219615 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0219369 |
| MAP7 | microtubule-associated protein 7 | 0.0218718 |
| LDHA | lactate dehydrogenase A | 0.0218469 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.021722 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0215966 |
| SETD5 | SET domain containing 5 | 0.0215477 |
| TMEM87A | transmembrane protein 87A | 0.0214869 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0214703 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.135529 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0697192 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0543814 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0431384 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0374337 |
| PKM | pyruvate kinase, muscle | -0.0352212 |
| EGFR | epidermal growth factor receptor | -0.0316542 |
| NDRG1 | N-myc downstream regulated 1 | -0.0316276 |
| CES1 | carboxylesterase 1 | -0.0304464 |
| SCEL | sciellin | -0.0285915 |
| PLEC | plectin | -0.0279839 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0266183 |
| SLC38A2 | solute carrier family 38, member 2 | -0.026317 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0261003 |
| LMO7 | LIM domain 7 | -0.0244999 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0230878 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0223006 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0217151 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0213654 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0205167 |
| MYOF | myoferlin | -0.0202513 |
| RNF213 | ring finger protein 213 | -0.0199704 |
| TNS3 | tensin 3 | -0.0182949 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0179812 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0175788 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0170267 |
| PTEN | phosphatase and tensin homolog | -0.0168238 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.016349 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0160532 |
| LAMA5 | laminin, alpha 5 | -0.0160254 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0159932 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0155191 |
| MGAT4C | MGAT4 family, member C | -0.015468 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0153702 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0153543 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0153395 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0145484 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0145175 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.014438 |
| EGR1 | early growth response 1 | -0.014217 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0139873 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0136263 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0136044 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.013454 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0133461 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0133418 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0132712 |
| HCFC1 | host cell factor C1 | -0.013121 |
| HMGA1 | high mobility group AT-hook 1 | -0.0131186 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0129555 |
| FLNA | filamin A, alpha | -0.0128397 |
| FLNB | filamin B, beta | -0.0126888 |
| TMSB10 | thymosin beta 10 | -0.0123355 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0122286 |
| FAT1 | FAT atypical cadherin 1 | -0.0121244 |
| EMP1 | epithelial membrane protein 1 | -0.0118596 |
| EXOC6B | exocyst complex component 6B | -0.0117885 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0116492 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0116251 |
| SMTN | smoothelin | -0.0115347 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0115255 |
| JUP | junction plakoglobin | -0.0114556 |
| HLA-A | major histocompatibility complex, class I, A | -0.0114293 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0113518 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0112885 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0112832 |
| TAPBP | TAP binding protein (tapasin) | -0.0112767 |
| GAK | cyclin G associated kinase | -0.0112729 |
| TRAPPC12 | trafficking protein particle complex 12 | -0.0112353 |
| AHNAK | AHNAK nucleoprotein | -0.0110965 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0110563 |
| EP400 | E1A binding protein p400 | -0.0110424 |
| MYEOV | myeloma overexpressed | -0.0109884 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.0108449 |
| CCND1 | cyclin D1 | -0.0107279 |
| ATN1 | atrophin 1 | -0.0107173 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0106824 |
| SETD1B | SET domain containing 1B | -0.0106574 |
| PHKB | phosphorylase kinase, beta | -0.0105997 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0105946 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0105925 |
| BCL9L | B-cell CLL/lymphoma 9-like | -0.0104828 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.01044 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0104284 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0103342 |
| SETX | senataxin | -0.0102834 |
| PFKL | phosphofructokinase, liver | -0.0102701 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0102091 |
| CPNE4 | copine IV | -0.0100435 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00998971 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.00998698 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0098799 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | -0.00982373 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | -0.00978323 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00974943 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.00970118 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.00966207 |
| CLDN7 | claudin 7 | -0.00964815 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.00958649 |
| USP25 | ubiquitin specific peptidase 25 | -0.00954925 |
