| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Proglumide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0732498 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0580126 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0412835 |
| GLCCI1 | glucocorticoid induced 1 | 0.0302837 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.028098 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0276236 |
| RNF145 | ring finger protein 145 | 0.0271363 |
| SIK3 | SIK family kinase 3 | 0.0244017 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.023492 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0233585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0225727 |
| RPS12 | ribosomal protein S12 | 0.0222351 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0212798 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0209238 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0203237 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0200152 |
| STK38L | serine/threonine kinase 38 like | 0.0198872 |
| RPS8 | ribosomal protein S8 | 0.0195814 |
| RPS6 | ribosomal protein S6 | 0.0194186 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0193832 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0193265 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0187854 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0186061 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0184482 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0182184 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0180458 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0177945 |
| MT2A | metallothionein 2A | 0.0170721 |
| VMP1 | vacuole membrane protein 1 | 0.0168151 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0166898 |
| NEK7 | NIMA-related kinase 7 | 0.016593 |
| OGA | O-GlcNAcase | 0.0165081 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0163503 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0159159 |
| RPL23 | ribosomal protein L23 | 0.0158749 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0158265 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0153001 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0152627 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0149917 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0147082 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0143274 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0134795 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0129704 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0128765 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.012868 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0120915 |
| RASA2 | RAS p21 protein activator 2 | 0.0120454 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0118972 |
| TOP1 | topoisomerase (DNA) I | 0.0116664 |
| SETD5 | SET domain containing 5 | 0.0115841 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0114152 |
| RPLP2 | ribosomal protein, large, P2 | 0.0112313 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0111352 |
| RPS2 | ribosomal protein S2 | 0.0110775 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0109817 |
| FBXO11 | F-box protein 11 | 0.0109584 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0108904 |
| FAM13A | family with sequence similarity 13, member A | 0.0108856 |
| RPL37A | ribosomal protein L37a | 0.0108675 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.01074 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0107305 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0107145 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0106919 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0105911 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0105694 |
| IFI44L | interferon-induced protein 44-like | 0.0105669 |
| PRSS3 | protease, serine, 3 | 0.0105125 |
| USP3 | ubiquitin specific peptidase 3 | 0.0103708 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0103154 |
| DTNA | dystrobrevin, alpha | 0.0102329 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0102004 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0101935 |
| AHR | aryl hydrocarbon receptor | 0.0101323 |
| DENR | density-regulated protein | 0.0100902 |
| SET | SET nuclear proto-oncogene | 0.0100707 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.010031 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0099401 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.00970801 |
| ATP13A3 | ATPase type 13A3 | 0.00968057 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.00967144 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00961787 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.00953568 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00950686 |
| RPS7 | ribosomal protein S7 | 0.00922192 |
| KIAA1958 | KIAA1958 | 0.00910183 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00907926 |
| TEX10 | testis expressed 10 | 0.00896992 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.00895568 |
| PNN | pinin, desmosome associated protein | 0.00894781 |
| CAB39 | calcium binding protein 39 | 0.00894625 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.00890787 |
| ETNK1 | ethanolamine kinase 1 | 0.00890763 |
| USP47 | ubiquitin specific peptidase 47 | 0.008902 |
| RPL5 | ribosomal protein L5 | 0.00886353 |
| LUZP1 | leucine zipper protein 1 | 0.00884051 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00875746 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00874946 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00874864 |
| RPS17 | ribosomal protein S17 | 0.0087359 |
| WDR26 | WD repeat domain 26 | 0.00873152 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.118267 |
| FN1 | fibronectin 1 | -0.0947197 |
| LOX | lysyl oxidase | -0.0886296 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0767006 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0694371 |
| USP34 | ubiquitin specific peptidase 34 | -0.0683829 |
| VIM | vimentin | -0.0655446 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0646334 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0636167 |
| GPC6 | glypican 6 | -0.0610076 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0601767 |
| SYT1 | synaptotagmin I | -0.059033 |
| CDH13 | cadherin 13 | -0.0545786 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0543137 |
| TMSB10 | thymosin beta 10 | -0.0530265 |
| DST | dystonin | -0.0454673 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0435512 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0421945 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0415385 |
| EXOC4 | exocyst complex component 4 | -0.0412067 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0411421 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0408315 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0407498 |
| ETV6 | ets variant 6 | -0.0394726 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0382595 |
| FBN1 | fibrillin 1 | -0.0381431 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0378117 |
| NDRG1 | N-myc downstream regulated 1 | -0.0373766 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0367142 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0355455 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0349017 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0346321 |
| EHBP1 | EH domain binding protein 1 | -0.0345947 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0340707 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0337044 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0335449 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0329558 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0323846 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0322634 |
| MECOM | MDS1 and EVI1 complex locus | -0.0321382 |
| MAP1B | microtubule-associated protein 1B | -0.0315809 |
| EGR1 | early growth response 1 | -0.031463 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0314546 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.031225 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305765 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0305417 |
| PRKCA | protein kinase C, alpha | -0.030533 |
| HDLBP | high density lipoprotein binding protein | -0.0305074 |
| CANX | calnexin | -0.0304697 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0301774 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0300938 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0300609 |
| FNIP1 | folliculin interacting protein 1 | -0.0300116 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0297423 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0290273 |
| ARF4 | ADP-ribosylation factor 4 | -0.0288523 |
| NRG1 | neuregulin 1 | -0.028498 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.028465 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0270441 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0270046 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0267576 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0267329 |
| CALU | calumenin | -0.0265778 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0265685 |
| RAD51B | RAD51 paralog B | -0.0263032 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0260823 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0256997 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.025649 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0255559 |
| PKM | pyruvate kinase, muscle | -0.0255357 |
| COPA | coatomer protein complex, subunit alpha | -0.0254324 |
| HDAC9 | histone deacetylase 9 | -0.0254023 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0253618 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0252663 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0251213 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0250879 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0244723 |
| BPTF | bromodomain PHD finger transcription factor | -0.0244536 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0243938 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0243715 |
| LRRC49 | leucine rich repeat containing 49 | -0.0240852 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0240615 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0239859 |
| PRELID2 | PRELI domain containing 2 | -0.0237486 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0235044 |
| MYO9A | myosin IXA | -0.0231572 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0231346 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.023047 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0229849 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0229457 |
| EGFR | epidermal growth factor receptor | -0.0226849 |
| PGK1 | phosphoglycerate kinase 1 | -0.022664 |
| CUX1 | cut-like homeobox 1 | -0.0226268 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.022434 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0224097 |
| ATXN1 | ataxin 1 | -0.0223855 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0223288 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0223286 |
| NF1 | neurofibromin 1 | -0.0222565 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0221896 |
