| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.123103 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0978254 |
| ANXA1 | annexin A1 | 0.0923355 |
| NDRG1 | N-myc downstream regulated 1 | 0.09157 |
| MT2A | metallothionein 2A | 0.0876896 |
| VMP1 | vacuole membrane protein 1 | 0.0860942 |
| VCL | vinculin | 0.0839334 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0826378 |
| STK24 | serine/threonine kinase 24 | 0.0812939 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0771778 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0745265 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0732527 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0709804 |
| IGF2 | insulin-like growth factor 2 | 0.0708147 |
| CA12 | carbonic anhydrase XII | 0.0696459 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0694721 |
| MYO1E | myosin IE | 0.0687169 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0684707 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0662275 |
| RASA2 | RAS p21 protein activator 2 | 0.0659496 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.065811 |
| RPS16 | ribosomal protein S16 | 0.0622444 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0618277 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0618206 |
| EPN2 | epsin 2 | 0.0614801 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0609631 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0595585 |
| METTL15 | methyltransferase like 15 | 0.0593337 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0590155 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.058554 |
| MYOF | myoferlin | 0.0583365 |
| ACTN4 | actinin, alpha 4 | 0.0569713 |
| ATXN1 | ataxin 1 | 0.0569318 |
| DTNA | dystrobrevin, alpha | 0.0562398 |
| RPL23 | ribosomal protein L23 | 0.0547092 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0542585 |
| INHBA | inhibin, beta A | 0.0542382 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0529682 |
| NAV1 | neuron navigator 1 | 0.0527954 |
| RNF149 | ring finger protein 149 | 0.0524084 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0514789 |
| ETF1 | eukaryotic translation termination factor 1 | 0.0512581 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0506734 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0505649 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0493343 |
| COPA | coatomer protein complex, subunit alpha | 0.0492437 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0485032 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0482222 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0480827 |
| NKTR | natural killer cell triggering receptor | 0.0480062 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0475202 |
| MEIS2 | Meis homeobox 2 | 0.0474934 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0471427 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0463535 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0459758 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0449962 |
| PTEN | phosphatase and tensin homolog | 0.0444349 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0438536 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0437742 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0436243 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0436089 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0433407 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0431313 |
| WDR45B | WD repeat domain 45B | 0.0428284 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0418444 |
| GLIS3 | GLIS family zinc finger 3 | 0.0417021 |
| SMAD3 | SMAD family member 3 | 0.0415044 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0413386 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0412538 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0410818 |
| MXD1 | MAX dimerization protein 1 | 0.0409066 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0407901 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0407634 |
| CDCP1 | CUB domain containing protein 1 | 0.0404654 |
| CMIP | c-Maf inducing protein | 0.0404239 |
| FAM193A | family with sequence similarity 193, member A | 0.0401652 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0401351 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0398369 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0390929 |
| MYO10 | myosin X | 0.0389712 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0381314 |
| PRELID2 | PRELI domain containing 2 | 0.0381285 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0376526 |
| IRS2 | insulin receptor substrate 2 | 0.0375459 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.036727 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0367112 |
| CORO1C | coronin, actin binding protein, 1C | 0.036255 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0356184 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0354505 |
| SSH1 | slingshot protein phosphatase 1 | 0.0353798 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.035021 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0350066 |
| FNBP1 | formin binding protein 1 | 0.0348123 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0347631 |
| CALU | calumenin | 0.0344917 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0343724 |
| JAK1 | Janus kinase 1 | 0.0343135 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0342519 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0342135 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0340747 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.189571 |
| FN1 | fibronectin 1 | -0.129305 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.126641 |
| VIM | vimentin | -0.108384 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0984782 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0951003 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0931449 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0905358 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0879226 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0877274 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.08457 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0799767 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0794763 |
| ZNF292 | zinc finger protein 292 | -0.0791139 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0772103 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0747949 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0669992 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0663337 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0661887 |
| GOLGA4 | golgin A4 | -0.0656181 |
| PDE10A | phosphodiesterase 10A | -0.0650562 |
| SVIL | supervillin | -0.0648479 |
| RPS6 | ribosomal protein S6 | -0.0645567 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0640803 |
| ATOSA | atos homolog A | -0.0636184 |
| TXNRD1 | thioredoxin reductase 1 | -0.0624967 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.061808 |
| TUSC3 | tumor suppressor candidate 3 | -0.0613594 |
| LDHA | lactate dehydrogenase A | -0.0607181 |
| SPAG9 | sperm associated antigen 9 | -0.0598239 |
| GPC6 | glypican 6 | -0.0596362 |
| CNKSR3 | CNKSR family member 3 | -0.0596172 |
| ASPH | aspartate beta-hydroxylase | -0.0596067 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0592701 |
| ZNF638 | zinc finger protein 638 | -0.0587606 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0583568 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0566676 |
| RPL8 | ribosomal protein L8 | -0.0566255 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0563892 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0563011 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0539502 |
| JMJD1C | jumonji domain containing 1C | -0.0537209 |
| INSIG1 | insulin induced gene 1 | -0.0536347 |
| RUNX1 | runt-related transcription factor 1 | -0.0526114 |
| ENO1 | enolase 1, (alpha) | -0.0521076 |
| DST | dystonin | -0.051901 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0516941 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0508778 |
| RTN4 | reticulon 4 | -0.0508297 |
| SFTPA2 | surfactant protein A2 | -0.0505623 |
| SRPK2 | SRSF protein kinase 2 | -0.0483032 |
| WAPL | WAPL cohesin release factor | -0.0471955 |
| KIF5B | kinesin family member 5B | -0.0467125 |
| POTEF | POTE ankyrin domain family, member F | -0.046409 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0460589 |
| RPLP1 | ribosomal protein, large, P1 | -0.0457368 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.045181 |
| USP33 | ubiquitin specific peptidase 33 | -0.0447185 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0441147 |
| PTMA | prothymosin, alpha | -0.0424552 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0420043 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0418188 |
| AHNAK | AHNAK nucleoprotein | -0.041815 |
| SMAD2 | SMAD family member 2 | -0.0411463 |
| FOXO1 | forkhead box O1 | -0.0401365 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397829 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0394248 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.03886 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0387657 |
| PTK2 | protein tyrosine kinase 2 | -0.0384829 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0375599 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0369379 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0369216 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0360439 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0358694 |
| AK1 | adenylate kinase 1 | -0.0356511 |
| MEF2A | myocyte enhancer factor 2A | -0.0356322 |
| SRP72 | signal recognition particle 72kDa | -0.0355856 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0354472 |
| SEPTIN7 | septin 7 | -0.0353055 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0350916 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0350047 |
| RBM47 | RNA binding motif protein 47 | -0.0333793 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0333737 |
| MUC16 | mucin 16, cell surface associated | -0.0333197 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0331114 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0329062 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0322999 |
| UBAP1 | ubiquitin associated protein 1 | -0.0319443 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0318306 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0317923 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0317423 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0313995 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0311222 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0310474 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0307191 |
| CALR | calreticulin | -0.0305534 |
| TMSB10 | thymosin beta 10 | -0.0304604 |
| RPS5 | ribosomal protein S5 | -0.0303168 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0302381 |
