| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.0569724 |
| HMGA1 | high mobility group AT-hook 1 | 0.0399755 |
| POTEF | POTE ankyrin domain family, member F | 0.0398814 |
| RPS12 | ribosomal protein S12 | 0.0347471 |
| RPLP2 | ribosomal protein, large, P2 | 0.0332819 |
| MT2A | metallothionein 2A | 0.0306979 |
| RPS23 | ribosomal protein S23 | 0.024918 |
| G0S2 | G0/G1 switch 2 | 0.0248139 |
| RPS13 | ribosomal protein S13 | 0.0243938 |
| RPL21 | ribosomal protein L21 | 0.0210516 |
| RPS8 | ribosomal protein S8 | 0.02099 |
| RPS6 | ribosomal protein S6 | 0.0200563 |
| RPS19 | ribosomal protein S19 | 0.0198998 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0187137 |
| GPX4 | glutathione peroxidase 4 | 0.0181298 |
| RNF145 | ring finger protein 145 | 0.0178457 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.017783 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.017668 |
| RPS29 | ribosomal protein S29 | 0.0173139 |
| PCBP2 | poly(rC) binding protein 2 | 0.0154053 |
| RPL12 | ribosomal protein L12 | 0.0151832 |
| PTMA | prothymosin, alpha | 0.0149415 |
| RPS27 | ribosomal protein S27 | 0.0149334 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0144712 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0142762 |
| RPL9 | ribosomal protein L9 | 0.0142066 |
| TMSB10 | thymosin beta 10 | 0.0141504 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0140796 |
| RPL18 | ribosomal protein L18 | 0.0139527 |
| COX7C | cytochrome c oxidase subunit VIIc | 0.0136773 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0136717 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0128823 |
| RPL5 | ribosomal protein L5 | 0.0128003 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0127268 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0123715 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0123681 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0122349 |
| MSN | moesin | 0.0121305 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0114096 |
| TMEM167A | transmembrane protein 167A | 0.0113873 |
| USP3 | ubiquitin specific peptidase 3 | 0.011378 |
| RPL28 | ribosomal protein L28 | 0.0113564 |
| RPL37 | ribosomal protein L37 | 0.0113114 |
| RPS15 | ribosomal protein S15 | 0.011222 |
| S100A9 | S100 calcium binding protein A9 | 0.0112128 |
| TFG | TRK-fused gene | 0.0111924 |
| NUP54 | nucleoporin 54kDa | 0.0111596 |
| RPL35A | ribosomal protein L35a | 0.0111409 |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.0111108 |
| MEF2A | myocyte enhancer factor 2A | 0.0109775 |
| FOSL1 | FOS-like antigen 1 | 0.0105703 |
| RPL27 | ribosomal protein L27 | 0.0104919 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0104856 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0104838 |
| SESN2 | sestrin 2 | 0.0103454 |
| ROMO1 | reactive oxygen species modulator 1 | 0.0103078 |
| S100A6 | S100 calcium binding protein A6 | 0.0101333 |
| RPS25 | ribosomal protein S25 | 0.0100768 |
| LDHB | lactate dehydrogenase B | 0.00976956 |
| RPS10 | ribosomal protein S10 | 0.00963569 |
| CD24 | CD24 molecule | 0.00961754 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.00960079 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | 0.00945016 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00937548 |
| WDR43 | WD repeat domain 43 | 0.00930309 |
| NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 0.00923278 |
| CCNL1 | cyclin L1 | 0.00921876 |
| RHOF | ras homolog family member F (in filopodia) | 0.00917678 |
| RCOR1 | REST corepressor 1 | 0.00902074 |
| OCIAD2 | OCIA domain containing 2 | 0.00893265 |
| RPS11 | ribosomal protein S11 | 0.00886241 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00883253 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.00876817 |
| SELENOT | selenoprotein T | 0.00876201 |
| RPL35 | ribosomal protein L35 | 0.00874963 |
| MYL12B | myosin, light chain 12B, regulatory | 0.00872387 |
| PML | promyelocytic leukemia | 0.00871162 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0087083 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.00861586 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00858979 |
| YY1AP1 | YY1 associated protein 1 | 0.00853443 |
| ZFP36 | ZFP36 ring finger protein | 0.00851449 |
| RPL36 | ribosomal protein L36 | 0.00842849 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00842577 |
| H1-4 | H1.4 linker histone, cluster member | 0.0084122 |
| ATP13A3 | ATPase type 13A3 | 0.00838692 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00831438 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00828434 |
| B2M | beta-2-microglobulin | 0.00825153 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00818559 |
| ATP11B | ATPase, class VI, type 11B | 0.00816468 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00812995 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.00807307 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.00800301 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.00788942 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.00782305 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.00778814 |
| COL1A1 | collagen, type I, alpha 1 | 0.00778532 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00774864 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | 0.00772349 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.171812 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125709 |
| LMO7 | LIM domain 7 | -0.0843193 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0671094 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0626447 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0619204 |
| EFNA5 | ephrin-A5 | -0.0618221 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0599495 |
| ACTG1 | actin gamma 1 | -0.0598008 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.059558 |
| NDRG1 | N-myc downstream regulated 1 | -0.0543042 |
| ERBIN | erbb2 interacting protein | -0.054233 |
| CANX | calnexin | -0.0539293 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0534437 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0520039 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0499892 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0492893 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0479241 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0458665 |
| ANXA2 | annexin A2 | -0.04553 |
| PGK1 | phosphoglycerate kinase 1 | -0.0448732 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0448324 |
| GRB10 | growth factor receptor-bound protein 10 | -0.04434 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0435442 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0433667 |
| UBC | ubiquitin C | -0.04282 |
| ASPH | aspartate beta-hydroxylase | -0.04261 |
| CD2AP | CD2-associated protein | -0.0410214 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0405649 |
| TMSB4X | thymosin beta 4, X-linked | -0.04011 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0399804 |
| MYOF | myoferlin | -0.0399118 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0379483 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0379346 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0378769 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.036481 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0358672 |
| PTK2 | protein tyrosine kinase 2 | -0.0356916 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0347904 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0343847 |
| MAP4 | microtubule-associated protein 4 | -0.0341917 |
| LDHA | lactate dehydrogenase A | -0.0337344 |
| PARD3 | par-3 family cell polarity regulator | -0.0337268 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0335263 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0329928 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0329549 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0328487 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0326163 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0318871 |
| TPM4 | tropomyosin 4 | -0.0312851 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0311304 |
| GNAS | GNAS complex locus | -0.0310754 |
| OCLN | occludin | -0.0310017 |
| ARF1 | ADP-ribosylation factor 1 | -0.0307273 |
| FNIP1 | folliculin interacting protein 1 | -0.0305718 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0304291 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0297436 |
| LAMC2 | laminin, gamma 2 | -0.029248 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0289939 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0286031 |
| RBM39 | RNA binding motif protein 39 | -0.0283895 |
| RRBP1 | ribosome binding protein 1 | -0.0282572 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0280674 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0279931 |
| EZR | ezrin | -0.0279673 |
| HMGB2 | high mobility group box 2 | -0.0279105 |
| FN1 | fibronectin 1 | -0.0278999 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.027897 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0277073 |
| CCND1 | cyclin D1 | -0.0276988 |
| FAM13A | family with sequence similarity 13, member A | -0.0275717 |
| PKM | pyruvate kinase, muscle | -0.0274565 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0273377 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0272287 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.027191 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.027005 |
| COPA | coatomer protein complex, subunit alpha | -0.0269424 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.026791 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0266011 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0265872 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0265676 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.026106 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0259887 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0259225 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0257971 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0257659 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0255991 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0255641 |
| AHNAK | AHNAK nucleoprotein | -0.0255619 |
| MYO1E | myosin IE | -0.0254104 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0253853 |
| CEP350 | centrosomal protein 350kDa | -0.0252449 |
| NAV2 | neuron navigator 2 | -0.0252404 |
| PLEC | plectin | -0.0249834 |
| OSMR | oncostatin M receptor | -0.0246909 |
| MYO6 | myosin VI | -0.0242516 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0241188 |
| EPCAM | epithelial cell adhesion molecule | -0.0240375 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0239865 |
| ATP11A | ATPase, class VI, type 11A | -0.0238902 |
