| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0775162 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.07716 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0769231 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0740702 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0732781 |
| GOLGA4 | golgin A4 | 0.0708433 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0692307 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0690199 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.061828 |
| EZR | ezrin | 0.061401 |
| TXNIP | thioredoxin interacting protein | 0.0593334 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0592901 |
| CENPF | centromere protein F, 350/400kDa | 0.0565983 |
| LDHA | lactate dehydrogenase A | 0.0521024 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0501384 |
| EFNA5 | ephrin-A5 | 0.0490005 |
| FLNB | filamin B, beta | 0.0481251 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.046706 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0465139 |
| MKI67 | marker of proliferation Ki-67 | 0.0457608 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0451207 |
| NFIA | nuclear factor I/A | 0.0440368 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0434889 |
| EVI5 | ecotropic viral integration site 5 | 0.0430019 |
| CANX | calnexin | 0.0418186 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0414587 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0411485 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0404069 |
| NAV2 | neuron navigator 2 | 0.0399529 |
| SBF2 | SET binding factor 2 | 0.0394842 |
| AHNAK | AHNAK nucleoprotein | 0.0389965 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0382443 |
| HJURP | Holliday junction recognition protein | 0.0369662 |
| BMP2K | BMP2 inducible kinase | 0.0369373 |
| PGK1 | phosphoglycerate kinase 1 | 0.0363151 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0352766 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0352083 |
| SET | SET nuclear proto-oncogene | 0.0348627 |
| PRELID2 | PRELI domain containing 2 | 0.03463 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0344601 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0343826 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0337313 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0335095 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0334443 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0328385 |
| TMF1 | TATA element modulatory factor 1 | 0.032668 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0324134 |
| USP34 | ubiquitin specific peptidase 34 | 0.0323232 |
| ENO1 | enolase 1, (alpha) | 0.0323016 |
| ZNF638 | zinc finger protein 638 | 0.0318959 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0315771 |
| VCL | vinculin | 0.0315713 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0305363 |
| TPM4 | tropomyosin 4 | 0.0303181 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0302373 |
| RNF145 | ring finger protein 145 | 0.0301327 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0301057 |
| JMJD1C | jumonji domain containing 1C | 0.0294742 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0293568 |
| SNX14 | sorting nexin 14 | 0.0293549 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0289413 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0286965 |
| KIF5B | kinesin family member 5B | 0.0285579 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0284837 |
| RAB6A | RAB6A, member RAS oncogene family | 0.028311 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0281465 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0280094 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.027759 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0276716 |
| TMEM65 | transmembrane protein 65 | 0.0273909 |
| GOLGB1 | golgin B1 | 0.0267527 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.026625 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0266242 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0266067 |
| NGLY1 | N-glycanase 1 | 0.0264561 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0263758 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0263236 |
| CALU | calumenin | 0.0260149 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0257752 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0257451 |
| ANXA1 | annexin A1 | 0.0256985 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0255561 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.025248 |
| ASPH | aspartate beta-hydroxylase | 0.0250916 |
| FAT1 | FAT atypical cadherin 1 | 0.0248273 |
| TMEM41B | transmembrane protein 41B | 0.0248269 |
| SQSTM1 | sequestosome 1 | 0.0248179 |
| PHF3 | PHD finger protein 3 | 0.0246403 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0246026 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0245942 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0244163 |
| TMEM14B | transmembrane protein 14B | 0.0244078 |
| TJP1 | tight junction protein 1 | 0.024221 |
| RHBDD1 | rhomboid domain containing 1 | 0.0241609 |
| YEATS2 | YEATS domain containing 2 | 0.0241411 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0240729 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.023996 |
| NF1 | neurofibromin 1 | 0.0238536 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0237761 |
| IL6ST | interleukin 6 signal transducer | 0.0232893 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | -0.167938 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0781824 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0678224 |
| RPL35A | ribosomal protein L35a | -0.0626085 |
| EGFR | epidermal growth factor receptor | -0.0588689 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0567999 |
| POTEF | POTE ankyrin domain family, member F | -0.053708 |
| RPLP1 | ribosomal protein, large, P1 | -0.0501948 |
| FOXP1 | forkhead box P1 | -0.046034 |
| RPL11 | ribosomal protein L11 | -0.0453046 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0442202 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0402471 |
| RPS6 | ribosomal protein S6 | -0.0402015 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0392499 |
| ACTG1 | actin gamma 1 | -0.0378548 |
| RPS19 | ribosomal protein S19 | -0.0368191 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0364762 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0346455 |
| BMP10 | bone morphogenetic protein 10 | -0.0341333 |
| RPS24 | ribosomal protein S24 | -0.0335937 |
| RPS8 | ribosomal protein S8 | -0.0335291 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0334577 |
| RPL23 | ribosomal protein L23 | -0.0323047 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0322975 |
| RPL19 | ribosomal protein L19 | -0.0319881 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0316384 |
| RPL13A | ribosomal protein L13a | -0.0315962 |
| TMSB10 | thymosin beta 10 | -0.0306696 |
| RPL34 | ribosomal protein L34 | -0.0303743 |
| RTN4 | reticulon 4 | -0.0302198 |
| RPL36 | ribosomal protein L36 | -0.0295939 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0289008 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0285318 |
| HDAC9 | histone deacetylase 9 | -0.0279626 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0279129 |
| RPL3 | ribosomal protein L3 | -0.027875 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0277763 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0271764 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0270509 |
| ZNF438 | zinc finger protein 438 | -0.0270313 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0269937 |
| RPL28 | ribosomal protein L28 | -0.0269514 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0269192 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0267215 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0265283 |
| RPL37A | ribosomal protein L37a | -0.0261259 |
| TAPBP | TAP binding protein (tapasin) | -0.0260747 |
| OSMR | oncostatin M receptor | -0.0250188 |
| SEPTIN9 | septin 9 | -0.0249202 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0248994 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0248526 |
| TFG | TRK-fused gene | -0.0247733 |
| CCNL1 | cyclin L1 | -0.0234834 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0230703 |
| PHF14 | PHD finger protein 14 | -0.0230441 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0229355 |
| PRDX2 | peroxiredoxin 2 | -0.0229036 |
| S100A9 | S100 calcium binding protein A9 | -0.0227673 |
| FMN1 | formin 1 | -0.022666 |
| GSE1 | Gse1 coiled-coil protein | -0.0225961 |
| RPL26 | ribosomal protein L26 | -0.0221381 |
| HMGA1 | high mobility group AT-hook 1 | -0.0219019 |
| PDE7B | phosphodiesterase 7B | -0.0218698 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0217873 |
| RPS4X | ribosomal protein S4, X-linked | -0.0216625 |
| TXNRD1 | thioredoxin reductase 1 | -0.0216281 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0215013 |
| GLI3 | GLI family zinc finger 3 | -0.0212052 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0211704 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0209774 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0206344 |
| RIGI | RNA sensor RIG-I | -0.020481 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | -0.0200834 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0200385 |
| MSI2 | musashi RNA-binding protein 2 | -0.019988 |
| RPS3 | ribosomal protein S3 | -0.0199766 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0197074 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0194413 |
| MLIP | muscular LMNA-interacting protein | -0.0193915 |
| DIAPH1 | diaphanous-related formin 1 | -0.0192735 |
| ACTN4 | actinin, alpha 4 | -0.0192513 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0192472 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.019007 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0189832 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0189033 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0188003 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0184321 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0182864 |
| RUNX1 | runt-related transcription factor 1 | -0.018285 |
| RPL5 | ribosomal protein L5 | -0.018224 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0181807 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | -0.0181776 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.01812 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0181135 |
| RPS16 | ribosomal protein S16 | -0.0178936 |
| RPL12 | ribosomal protein L12 | -0.0178017 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0176714 |
| FBLN2 | fibulin 2 | -0.0176414 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0176018 |
| ECT2 | epithelial cell transforming 2 | -0.0175656 |
