| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.151093 |
| VEGFA | vascular endothelial growth factor A | 0.100296 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0790562 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0699337 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0672526 |
| ADM | adrenomedullin | 0.0598796 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0542815 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0542321 |
| VMP1 | vacuole membrane protein 1 | 0.0538441 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0530607 |
| MSN | moesin | 0.0529397 |
| ARRDC3 | arrestin domain containing 3 | 0.0525366 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0504975 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.04837 |
| TXNIP | thioredoxin interacting protein | 0.0481642 |
| NDRG1 | N-myc downstream regulated 1 | 0.047899 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0478677 |
| GOLGA4 | golgin A4 | 0.0464771 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0460806 |
| MYOF | myoferlin | 0.0459901 |
| BRD2 | bromodomain containing 2 | 0.0425017 |
| PLIN2 | perilipin 2 | 0.0409838 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0400996 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0393412 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0385079 |
| JMJD1C | jumonji domain containing 1C | 0.038095 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0375577 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0373853 |
| RND3 | Rho family GTPase 3 | 0.0370644 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0364998 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0360232 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0357367 |
| FTL | ferritin, light polypeptide | 0.0343498 |
| FBXO32 | F-box protein 32 | 0.0341838 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0338254 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0330989 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0328804 |
| ARFGEF3 | ARFGEF family member 3 | 0.0328154 |
| SQSTM1 | sequestosome 1 | 0.0320895 |
| OPTN | optineurin | 0.0311124 |
| RPS12 | ribosomal protein S12 | 0.0309807 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0302253 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0297678 |
| DUSP5 | dual specificity phosphatase 5 | 0.0293369 |
| CDK19 | cyclin-dependent kinase 19 | 0.0292741 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0277616 |
| ZNF292 | zinc finger protein 292 | 0.0276587 |
| MMP12 | matrix metallopeptidase 12 | 0.0275954 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0274311 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0259664 |
| CCNL1 | cyclin L1 | 0.0259003 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0255176 |
| ZNF638 | zinc finger protein 638 | 0.0251087 |
| B2M | beta-2-microglobulin | 0.0248297 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0248208 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.0244726 |
| ZNF654 | zinc finger protein 654 | 0.0243276 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0242733 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.024216 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.02414 |
| OGA | O-GlcNAcase | 0.0238386 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0237327 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0237121 |
| FAM13A | family with sequence similarity 13, member A | 0.023584 |
| KLHL24 | kelch-like family member 24 | 0.0232913 |
| FLNB | filamin B, beta | 0.0232379 |
| STC1 | stanniocalcin 1 | 0.023203 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0225891 |
| RPL21 | ribosomal protein L21 | 0.0216914 |
| YEATS2 | YEATS domain containing 2 | 0.0214927 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0211888 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0211831 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0211523 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.020792 |
| RPS2 | ribosomal protein S2 | 0.0207602 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0205776 |
| UBC | ubiquitin C | 0.0203704 |
| NAV2 | neuron navigator 2 | 0.020292 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0201949 |
| NGLY1 | N-glycanase 1 | 0.0201724 |
| TMF1 | TATA element modulatory factor 1 | 0.0201278 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0200362 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0200107 |
| SETD5 | SET domain containing 5 | 0.019923 |
| UBE4B | ubiquitination factor E4B | 0.0193394 |
| SPAG9 | sperm associated antigen 9 | 0.0192774 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0192134 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0188324 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187392 |
| NOTCH2 | notch 2 | 0.0187309 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0186929 |
| HELZ | helicase with zinc finger | 0.0186463 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0186072 |
| RNF24 | ring finger protein 24 | 0.0185365 |
| CERT1 | ceramide transporter 1 | 0.0183916 |
| FOXO3 | forkhead box O3 | 0.0183517 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0180661 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0179188 |
| ZNF395 | zinc finger protein 395 | 0.017904 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0177958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GLIS3 | GLIS family zinc finger 3 | -0.228678 |
| FN1 | fibronectin 1 | -0.211662 |
| FRMD4A | FERM domain containing 4A | -0.17032 |
| EXT1 | exostosin glycosyltransferase 1 | -0.142124 |
| COL6A3 | collagen, type VI, alpha 3 | -0.124578 |
| DST | dystonin | -0.117444 |
| BICC1 | BicC family RNA binding protein 1 | -0.116465 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.114332 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.102226 |
| HMGA2 | high mobility group AT-hook 2 | -0.0957209 |
| CDH13 | cadherin 13 | -0.094449 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.089012 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0882655 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0762991 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0761922 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0737912 |
| VIM | vimentin | -0.0732984 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0700793 |
| AHNAK | AHNAK nucleoprotein | -0.0669163 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0645566 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0639135 |
| DIAPH2 | diaphanous-related formin 2 | -0.0624696 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0623297 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0615884 |
| RNF213 | ring finger protein 213 | -0.0599875 |
| CD44 | CD44 molecule (Indian blood group) | -0.0594821 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.058661 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.057375 |
| THBS1 | thrombospondin 1 | -0.0566918 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0551992 |
| COL1A1 | collagen, type I, alpha 1 | -0.0550755 |
| HLA-B | major histocompatibility complex, class I, B | -0.0549637 |
| TNS3 | tensin 3 | -0.0538503 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0523588 |
| FOXP1 | forkhead box P1 | -0.0517736 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0512501 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0509304 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0509175 |
| SMYD3 | SET and MYND domain containing 3 | -0.0507046 |
| EFNA5 | ephrin-A5 | -0.049873 |
| SMAD3 | SMAD family member 3 | -0.0498566 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0497367 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0490154 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0478889 |
| RAI14 | retinoic acid induced 14 | -0.0478253 |
| ATXN1 | ataxin 1 | -0.0477274 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0477242 |
| NAV1 | neuron navigator 1 | -0.047367 |
| FAM20C | family with sequence similarity 20, member C | -0.044796 |
| TXNRD1 | thioredoxin reductase 1 | -0.0444062 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0443022 |
| COL5A1 | collagen, type V, alpha 1 | -0.0442926 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0434079 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0426185 |
| TPM1 | tropomyosin 1 (alpha) | -0.0418942 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0405085 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0404395 |
| IER3 | immediate early response 3 | -0.0402443 |
| RIGI | RNA sensor RIG-I | -0.0398592 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.039542 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0391456 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0390571 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0388875 |
| VCAN | versican | -0.0384168 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0378829 |
| CEP112 | centrosomal protein 112kDa | -0.0376084 |
| CADM1 | cell adhesion molecule 1 | -0.0368619 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0366652 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0365022 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.036361 |
| ATG7 | autophagy related 7 | -0.0361019 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0360396 |
| GPC6 | glypican 6 | -0.035921 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0353908 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0349559 |
| TNNC1 | troponin C type 1 (slow) | -0.0348621 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0340813 |
| CALR | calreticulin | -0.0339894 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0338684 |
| THBS2 | thrombospondin 2 | -0.033609 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0332015 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0330931 |
| NRP1 | neuropilin 1 | -0.032928 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0327775 |
| MAP1B | microtubule-associated protein 1B | -0.0325616 |
| TMSB4X | thymosin beta 4, X-linked | -0.0323541 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0323175 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0322519 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.032125 |
| TMEM132D | transmembrane protein 132D | -0.0320832 |
| PLCB4 | phospholipase C, beta 4 | -0.0320408 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0317237 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0317078 |
| TMSB10 | thymosin beta 10 | -0.0314248 |
| EXOC4 | exocyst complex component 4 | -0.0314194 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0314067 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0313714 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.031297 |
| EHBP1 | EH domain binding protein 1 | -0.0312631 |
| COL1A2 | collagen, type I, alpha 2 | -0.0312568 |
