| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0661772 |
| B2M | beta-2-microglobulin | 0.062467 |
| FAM13A | family with sequence similarity 13, member A | 0.0575578 |
| VEGFA | vascular endothelial growth factor A | 0.0566652 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0528864 |
| ATP13A3 | ATPase type 13A3 | 0.0474257 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0469872 |
| ARRDC3 | arrestin domain containing 3 | 0.0445304 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0428743 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0427725 |
| RNF145 | ring finger protein 145 | 0.0426161 |
| RYBP | RING1 and YY1 binding protein | 0.0420759 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0414986 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0414848 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0405317 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.040442 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0403984 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0400647 |
| COPA | coatomer protein complex, subunit alpha | 0.039825 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0391744 |
| GOLGA4 | golgin A4 | 0.0389786 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0387688 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0386945 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0367744 |
| CALR | calreticulin | 0.0364049 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0362534 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.03618 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0356854 |
| MSN | moesin | 0.0347791 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0347038 |
| SRP54 | signal recognition particle 54kDa | 0.03335 |
| XPO1 | exportin 1 | 0.0332682 |
| TMEM167A | transmembrane protein 167A | 0.0330941 |
| ZNF148 | zinc finger protein 148 | 0.0330823 |
| NOP58 | NOP58 ribonucleoprotein | 0.0325947 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0323732 |
| IL6 | interleukin 6 | 0.0323072 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0321663 |
| TPM2 | tropomyosin 2 (beta) | 0.0320385 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0315947 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0312741 |
| PHF21A | PHD finger protein 21A | 0.0311492 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0310386 |
| HOMER2 | homer scaffolding protein 2 | 0.0305713 |
| RPS6 | ribosomal protein S6 | 0.0302061 |
| OPTN | optineurin | 0.0301116 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0297882 |
| SETD5 | SET domain containing 5 | 0.0295315 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.029467 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0287609 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0286325 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0284378 |
| RIOK3 | RIO kinase 3 | 0.0284095 |
| RPL12 | ribosomal protein L12 | 0.028384 |
| RPS8 | ribosomal protein S8 | 0.0283184 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0281858 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0281377 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0279122 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0278819 |
| FOSL1 | FOS-like antigen 1 | 0.0273507 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0272533 |
| RORA | RAR-related orphan receptor A | 0.0271415 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0269837 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0269541 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0268881 |
| RPL21 | ribosomal protein L21 | 0.0266111 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0265943 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0265587 |
| MTREX | Mtr4 exosome RNA helicase | 0.0263537 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0263472 |
| TMEM39A | transmembrane protein 39A | 0.0263306 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0262848 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0262166 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0262052 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0261203 |
| VGLL4 | vestigial-like family member 4 | 0.0259448 |
| CCNI | cyclin I | 0.0259049 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0258965 |
| CD109 | CD109 molecule | 0.0257258 |
| PTGES2 | prostaglandin E synthase 2 | 0.0256539 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0254766 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0253921 |
| NME7 | NME/NM23 family member 7 | 0.0253002 |
| COG6 | component of oligomeric golgi complex 6 | 0.0252504 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0252215 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0251838 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0251068 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0250916 |
| PAPOLA | poly(A) polymerase alpha | 0.0250205 |
| RARS2 | arginyl-tRNA synthetase 2, mitochondrial | 0.0250147 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0249994 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0249153 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0247582 |
| CST3 | cystatin C | 0.0247456 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0246293 |
| NRBP1 | nuclear receptor binding protein 1 | 0.0245377 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0243324 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0242999 |
| RACK1 | receptor for activated C kinase 1 | 0.0240159 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0240075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.296062 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.215764 |
| FN1 | fibronectin 1 | -0.161835 |
| VIM | vimentin | -0.0998637 |
| GLIS3 | GLIS family zinc finger 3 | -0.0997411 |
| HLA-B | major histocompatibility complex, class I, B | -0.0966485 |
| LOXL2 | lysyl oxidase-like 2 | -0.0954859 |
| TMSB10 | thymosin beta 10 | -0.0952978 |
| HMGA2 | high mobility group AT-hook 2 | -0.0949149 |
| AHNAK | AHNAK nucleoprotein | -0.0916684 |
| LOX | lysyl oxidase | -0.0805536 |
| COL5A1 | collagen, type V, alpha 1 | -0.0779696 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0763798 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0753428 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0726539 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0665537 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.066052 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0660291 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0659929 |
| VCL | vinculin | -0.0624754 |
| CALD1 | caldesmon 1 | -0.0624592 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0604999 |
| CDK6 | cyclin-dependent kinase 6 | -0.0596627 |
| ASPH | aspartate beta-hydroxylase | -0.0567647 |
| NRXN3 | neurexin 3 | -0.0543473 |
| RASAL2 | RAS protein activator like 2 | -0.0540015 |
| CLTC | clathrin, heavy chain (Hc) | -0.0523681 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0517502 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.051707 |
| AOPEP | aminopeptidase O (putative) | -0.0510814 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0503933 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0499151 |
| TPM4 | tropomyosin 4 | -0.0496446 |
| CALU | calumenin | -0.047869 |
| MAP4 | microtubule-associated protein 4 | -0.0476001 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0475816 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0475136 |
| CDH13 | cadherin 13 | -0.0471981 |
| ANXA2 | annexin A2 | -0.0471323 |
| NRP1 | neuropilin 1 | -0.0455983 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.045284 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0451122 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0448133 |
| FAM20C | family with sequence similarity 20, member C | -0.0442235 |
| VEGFC | vascular endothelial growth factor C | -0.0434729 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0434349 |
| CD44 | CD44 molecule (Indian blood group) | -0.0426958 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0410765 |
| OSMR | oncostatin M receptor | -0.0403956 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0398048 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0389529 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0385694 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0383093 |
| AHR | aryl hydrocarbon receptor | -0.0382039 |
| CADM1 | cell adhesion molecule 1 | -0.0381983 |
| CUL3 | cullin 3 | -0.0376627 |
| TNNC1 | troponin C type 1 (slow) | -0.0376037 |
| USP34 | ubiquitin specific peptidase 34 | -0.0374803 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0372474 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0371927 |
| PTK2 | protein tyrosine kinase 2 | -0.0371674 |
| SRPK2 | SRSF protein kinase 2 | -0.0365753 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0364445 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | -0.0359906 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0359378 |
| SMAD3 | SMAD family member 3 | -0.0357706 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0355429 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0350498 |
| RAI14 | retinoic acid induced 14 | -0.0350174 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0350123 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0346005 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0343722 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0342525 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0339614 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0334667 |
| ETV6 | ets variant 6 | -0.0330562 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0320955 |
| SETBP1 | SET binding protein 1 | -0.0320582 |
| CAVIN1 | caveolae associated protein 1 | -0.0320353 |
| FLNA | filamin A, alpha | -0.0320236 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0319848 |
| TNS3 | tensin 3 | -0.0319353 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0318152 |
| ENO1 | enolase 1, (alpha) | -0.0315818 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.031579 |
| APP | amyloid beta (A4) precursor protein | -0.0315423 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0315143 |
| RPL35A | ribosomal protein L35a | -0.0315078 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0314806 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.031409 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0313649 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0311466 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.031002 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0308119 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0306092 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0305999 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0305866 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0305758 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0305667 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301961 |
