| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.339977 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0969773 |
| VIM | vimentin | 0.0831051 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0782407 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0763588 |
| YBX3 | Y box binding protein 3 | 0.0651096 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0614217 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0584814 |
| NUP58 | nucleoporin 58 | 0.0583817 |
| GOLGA4 | golgin A4 | 0.0581002 |
| CENPF | centromere protein F, 350/400kDa | 0.0555109 |
| ZNF292 | zinc finger protein 292 | 0.0554131 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0546287 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0510449 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0489626 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0473399 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0454531 |
| RBM39 | RNA binding motif protein 39 | 0.0447085 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0438219 |
| TXNIP | thioredoxin interacting protein | 0.0418107 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0416056 |
| DEK | DEK proto-oncogene | 0.0412239 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0405289 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.040489 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.040006 |
| SETD5 | SET domain containing 5 | 0.0393614 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0389685 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0382932 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0366387 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0366256 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0362223 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0357647 |
| PHF20 | PHD finger protein 20 | 0.0352148 |
| RPL23 | ribosomal protein L23 | 0.0346845 |
| THOC2 | THO complex 2 | 0.0346117 |
| TPX2 | TPX2, microtubule-associated | 0.0341006 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0340757 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0338147 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0332861 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.03234 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0322571 |
| CANX | calnexin | 0.031845 |
| LDHA | lactate dehydrogenase A | 0.0317928 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0315146 |
| KIF4A | kinesin family member 4A | 0.0314297 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313117 |
| RBM25 | RNA binding motif protein 25 | 0.0312392 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0308497 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0306141 |
| ECT2 | epithelial cell transforming 2 | 0.0305214 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0301854 |
| KIAA1328 | KIAA1328 | 0.0297725 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0297484 |
| KIAA1958 | KIAA1958 | 0.0297415 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0294353 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.0293381 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0289651 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.028846 |
| RPS3 | ribosomal protein S3 | 0.0287927 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0286337 |
| SPAG9 | sperm associated antigen 9 | 0.028399 |
| MATR3 | matrin 3 | 0.0278236 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0278056 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0276408 |
| NGLY1 | N-glycanase 1 | 0.0275087 |
| TXNRD1 | thioredoxin reductase 1 | 0.0274826 |
| SEPTIN7 | septin 7 | 0.027457 |
| VMP1 | vacuole membrane protein 1 | 0.0274097 |
| RANBP2 | RAN binding protein 2 | 0.0273118 |
| OSMR | oncostatin M receptor | 0.0272779 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0271496 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0270823 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0269307 |
| AXL | AXL receptor tyrosine kinase | 0.0268794 |
| RNF145 | ring finger protein 145 | 0.0267628 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0265887 |
| SGO2 | shugoshin 2 | 0.0265468 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0265003 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0263764 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0261464 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0260505 |
| MKI67 | marker of proliferation Ki-67 | 0.0259611 |
| SETD2 | SET domain containing 2 | 0.0258882 |
| HJURP | Holliday junction recognition protein | 0.0257625 |
| OGA | O-GlcNAcase | 0.0253198 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0252087 |
| RRBP1 | ribosome binding protein 1 | 0.025155 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0251005 |
| SNX14 | sorting nexin 14 | 0.0248053 |
| H3-3B | H3.3 histone B | 0.024791 |
| CEP295 | centrosomal protein 295kDa | 0.0247473 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.024649 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0246139 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0245259 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0244236 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0243733 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0243364 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.0242368 |
| CENPE | centromere protein E, 312kDa | 0.0241517 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0239821 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0994985 |
| HMGA2 | high mobility group AT-hook 2 | -0.0744046 |
| PKM | pyruvate kinase, muscle | -0.0528464 |
| INTS6 | integrator complex subunit 6 | -0.0525181 |
| MT2A | metallothionein 2A | -0.0520214 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0506963 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0478088 |
| EGR1 | early growth response 1 | -0.0450992 |
| FTL | ferritin, light polypeptide | -0.0396046 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0374936 |
| PODXL | podocalyxin-like | -0.0373662 |
| HLA-B | major histocompatibility complex, class I, B | -0.0362452 |
| COL5A1 | collagen, type V, alpha 1 | -0.0349682 |
| MAP1B | microtubule-associated protein 1B | -0.034694 |
| LAMA5 | laminin, alpha 5 | -0.0343739 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0342177 |
| PRKCA | protein kinase C, alpha | -0.0331149 |
| CCNH | cyclin H | -0.0326622 |
| CD44 | CD44 molecule (Indian blood group) | -0.0311661 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0308452 |
| LOC112694756 | uncharaterized LOC112694756 | -0.029903 |
| POTEF | POTE ankyrin domain family, member F | -0.0298087 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0295029 |
| TMSB10 | thymosin beta 10 | -0.0286413 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0282508 |
| HM13 | histocompatibility (minor) 13 | -0.0279438 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0278744 |
| CCND1 | cyclin D1 | -0.027693 |
| PRSS23 | protease, serine, 23 | -0.0265894 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0261074 |
| AEBP2 | AE binding protein 2 | -0.0260967 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0255741 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0254274 |
| RORA | RAR-related orphan receptor A | -0.0253027 |
| PCNX2 | pecanex 2 | -0.0252091 |
| IGF2 | insulin-like growth factor 2 | -0.0250132 |
| RIGI | RNA sensor RIG-I | -0.0249055 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0244942 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0244503 |
| HDAC9 | histone deacetylase 9 | -0.0236889 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0230948 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.022856 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0227495 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.022731 |
| TBCA | tubulin folding cofactor A | -0.0227282 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0224293 |
| ITGB4 | integrin, beta 4 | -0.0219064 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0218457 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.021548 |
| NAV2 | neuron navigator 2 | -0.0214248 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0213872 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0211116 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0210769 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0210482 |
| RPS29 | ribosomal protein S29 | -0.0209037 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.0207818 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0207532 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.02075 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0205238 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.020443 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0204048 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0202691 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0202335 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.020178 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0200961 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | -0.0199744 |
| RPS11 | ribosomal protein S11 | -0.0198851 |
| SUMF1 | sulfatase modifying factor 1 | -0.0197866 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0196775 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0195313 |
| SETX | senataxin | -0.0194196 |
| FAM120B | family with sequence similarity 120B | -0.0193932 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0192482 |
| TNS3 | tensin 3 | -0.0190637 |
| RPL19 | ribosomal protein L19 | -0.0188839 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0187499 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0186269 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0185186 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0185131 |
| RAD51B | RAD51 paralog B | -0.0184805 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | -0.0183797 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | -0.0181918 |
| BRD4 | bromodomain containing 4 | -0.0181827 |
| FNIP1 | folliculin interacting protein 1 | -0.0180434 |
| RAI14 | retinoic acid induced 14 | -0.0180387 |
| FRMD6 | FERM domain containing 6 | -0.0180225 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0179193 |
| RNF213 | ring finger protein 213 | -0.017836 |
| PRR16 | proline rich 16 | -0.0177202 |
| PKP4 | plakophilin 4 | -0.0174988 |
| HDLBP | high density lipoprotein binding protein | -0.0174775 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0174114 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0173742 |
| NRG1 | neuregulin 1 | -0.0173513 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0172222 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0172012 |
| HLA-C | major histocompatibility complex, class I, C | -0.0169431 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0169183 |
| ATG7 | autophagy related 7 | -0.0168275 |
| USO1 | USO1 vesicle transport factor | -0.0167513 |
