| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Proglumide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Proglumide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.146723 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0931263 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0697259 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0679235 |
| TXNIP | thioredoxin interacting protein | 0.0677232 |
| TPR | translocated promoter region, nuclear basket protein | 0.0668702 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0664497 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0659834 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0584527 |
| VMP1 | vacuole membrane protein 1 | 0.0532143 |
| RBM39 | RNA binding motif protein 39 | 0.0496005 |
| EREG | epiregulin | 0.0490706 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0482799 |
| VCL | vinculin | 0.0467682 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0465356 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0440898 |
| GOLGA4 | golgin A4 | 0.0440641 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0422914 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0414689 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0405662 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0389282 |
| TOP1 | topoisomerase (DNA) I | 0.0386697 |
| SETD5 | SET domain containing 5 | 0.0378656 |
| SQSTM1 | sequestosome 1 | 0.037795 |
| RBM25 | RNA binding motif protein 25 | 0.0360834 |
| OGA | O-GlcNAcase | 0.0350064 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0348259 |
| DUSP5 | dual specificity phosphatase 5 | 0.0347797 |
| RRBP1 | ribosome binding protein 1 | 0.0341183 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.03236 |
| ATXN2 | ataxin 2 | 0.031474 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0310952 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0309276 |
| TMF1 | TATA element modulatory factor 1 | 0.0307505 |
| VEGFA | vascular endothelial growth factor A | 0.0304098 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.03038 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.030277 |
| WDR26 | WD repeat domain 26 | 0.029847 |
| TMEM156 | transmembrane protein 156 | 0.0293796 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0281294 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0281264 |
| JMJD1C | jumonji domain containing 1C | 0.0280425 |
| TMEM263 | transmembrane protein 263 | 0.0279502 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0273805 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0273668 |
| NTN4 | netrin 4 | 0.0272476 |
| AREG | amphiregulin | 0.0271134 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0270147 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0269585 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0268015 |
| FBXO32 | F-box protein 32 | 0.026533 |
| PALLD | palladin, cytoskeletal associated protein | 0.0260202 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0257964 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0255512 |
| CREBRF | CREB3 regulatory factor | 0.0251942 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0250022 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0248876 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0248083 |
| SEC24A | SEC24 family member A | 0.0246603 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0246411 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0246299 |
| GOLM2 | golgi membrane protein 2 | 0.0245682 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0243476 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0243185 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0241948 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0240001 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0239897 |
| SRP54 | signal recognition particle 54kDa | 0.0238932 |
| ATP13A3 | ATPase type 13A3 | 0.0238468 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0238363 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0237511 |
| KSR1 | kinase suppressor of ras 1 | 0.0237046 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0233455 |
| RPS12 | ribosomal protein S12 | 0.0233114 |
| TMEM41B | transmembrane protein 41B | 0.0230682 |
| HPCAL1 | hippocalcin-like 1 | 0.0230003 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0228986 |
| SMAD3 | SMAD family member 3 | 0.0227808 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0226189 |
| SBF2 | SET binding factor 2 | 0.0226066 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0225721 |
| CDC27 | cell division cycle 27 | 0.0225413 |
| IL6ST | interleukin 6 signal transducer | 0.0224394 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0223571 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0222952 |
| SUCO | SUN domain containing ossification factor | 0.0221201 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219046 |
| ANXA5 | annexin A5 | 0.0218659 |
| CEP350 | centrosomal protein 350kDa | 0.0218485 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0217489 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0216393 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0214221 |
| THOC2 | THO complex 2 | 0.0210591 |
| KIF5B | kinesin family member 5B | 0.0209385 |
| SMOX | spermine oxidase | 0.0208564 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0206372 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0204209 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0202982 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0201903 |
| CUL3 | cullin 3 | 0.0199979 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224271 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.202519 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.172665 |
| NRG1 | neuregulin 1 | -0.158333 |
| NDRG1 | N-myc downstream regulated 1 | -0.129798 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.127015 |
| TMSB10 | thymosin beta 10 | -0.113986 |
| FN1 | fibronectin 1 | -0.111627 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0909193 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0828929 |
| PTMA | prothymosin, alpha | -0.0818122 |
| CADM1 | cell adhesion molecule 1 | -0.0655791 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0645082 |
| VIM | vimentin | -0.0623096 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0613326 |
| HLA-B | major histocompatibility complex, class I, B | -0.0578998 |
| RPL35A | ribosomal protein L35a | -0.0556373 |
| PKM | pyruvate kinase, muscle | -0.0555932 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0547767 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0538713 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0524459 |
| HMGA2 | high mobility group AT-hook 2 | -0.0509981 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0509958 |
| STC2 | stanniocalcin 2 | -0.0503202 |
| HMGA1 | high mobility group AT-hook 1 | -0.0501354 |
| MAP1B | microtubule-associated protein 1B | -0.0494096 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0468958 |
| FTL | ferritin, light polypeptide | -0.0454228 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0450404 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.044714 |
| LOX | lysyl oxidase | -0.0415325 |
| SFTPA2 | surfactant protein A2 | -0.0400753 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0400662 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0399785 |
| LMNA | lamin A/C | -0.0398601 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397829 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0386553 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.038543 |
| UBC | ubiquitin C | -0.0384894 |
| POTEF | POTE ankyrin domain family, member F | -0.0383495 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0380683 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0380397 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0375795 |
| CALU | calumenin | -0.037464 |
| CANX | calnexin | -0.0368687 |
| GLIS3 | GLIS family zinc finger 3 | -0.0357275 |
| COPA | coatomer protein complex, subunit alpha | -0.0343119 |
| AEBP2 | AE binding protein 2 | -0.0342525 |
| PGK1 | phosphoglycerate kinase 1 | -0.0329995 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0328833 |
| S100A6 | S100 calcium binding protein A6 | -0.0322353 |
| TMSB4X | thymosin beta 4, X-linked | -0.0310742 |
| S100A10 | S100 calcium binding protein A10 | -0.0309033 |
| DNM1L | dynamin 1-like | -0.030351 |
| PFN1 | profilin 1 | -0.0302874 |
| INTS6 | integrator complex subunit 6 | -0.0301476 |
| CENPF | centromere protein F, 350/400kDa | -0.0294977 |
| PTK2 | protein tyrosine kinase 2 | -0.0294971 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0290696 |
| SDCBP | syndecan binding protein (syntenin) | -0.0285204 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0284892 |
| BSG | basigin (Ok blood group) | -0.0279294 |
| TAGLN2 | transgelin 2 | -0.0278165 |
| LDHA | lactate dehydrogenase A | -0.0268855 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0268664 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0268159 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0267972 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0266234 |
| AHNAK | AHNAK nucleoprotein | -0.0266081 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0263964 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0261211 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0260317 |
| FLNA | filamin A, alpha | -0.0258708 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0258244 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0257056 |
| CTSD | cathepsin D | -0.025629 |
| RPS5 | ribosomal protein S5 | -0.0252218 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0249858 |
| RPL37 | ribosomal protein L37 | -0.0249514 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0249344 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0246789 |
| ACTG1 | actin gamma 1 | -0.0245422 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0245232 |
| HLA-A | major histocompatibility complex, class I, A | -0.0241142 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0240019 |
| RPS20 | ribosomal protein S20 | -0.0237768 |
| RNF213 | ring finger protein 213 | -0.0234642 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0230744 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0230129 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.022938 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0229219 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.0228918 |
| RASAL2 | RAS protein activator like 2 | -0.0227618 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.0227424 |
| RPL26 | ribosomal protein L26 | -0.0226996 |
| CALR | calreticulin | -0.0223074 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0219071 |
| RPL31 | ribosomal protein L31 | -0.0218755 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.021606 |
| NPR2 | natriuretic peptide receptor 2 | -0.0215808 |
