Progression Of Prostate Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1739135
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Genes

350 genes associated with the disease Progression Of Prostate Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACP3 acid phosphatase 3
ACTB actin, beta
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT1 angiopoietin 1
ANKRD22 ankyrin repeat domain 22
ANXA2 annexin A2
APLN apelin
AQP5 aquaporin 5
AR androgen receptor
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2 B-cell CLL/lymphoma 2
BCO2 beta-carotene oxygenase 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC2 baculoviral IAP repeat containing 2
BMP7 bone morphogenetic protein 7
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
C1ORF52 chromosome 1 open reading frame 52
C1QBP complement component 1, q subcomponent binding protein
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCNA1 cyclin A1
CCND1 cyclin D1
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD82 CD82 molecule
CD8A CD8a molecule
CDC20 cell division cycle 20
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFL1 cofilin 1 (non-muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CHD1 chromodomain helicase DNA binding protein 1
CHGA chromogranin A
CLDN8 claudin 8
CLOCK clock circadian regulator
CNN2 calponin 2
CNTN1 contactin 1
CNTNAP4 contactin associated protein-like 4
COL18A1 collagen, type XVIII, alpha 1
COMP cartilage oligomeric matrix protein
COX14 COX14 cytochrome c oxidase assembly factor
COX2
CST3 cystatin C
CST6 cystatin E/M
CTCF CCCTC-binding factor (zinc finger protein)
CTNND2 catenin (cadherin-associated protein), delta 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDR1 discoidin domain receptor tyrosine kinase 1
DEK DEK proto-oncogene
DLX1 distal-less homeobox 1
DPT dermatopontin
DST dystonin
E2F5 E2F transcription factor 5, p130-binding
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR3 early growth response 3
EIF4E eukaryotic translation initiation factor 4E
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELL2 elongation factor, RNA polymerase II, 2
ELOC elongin C
EP300 E1A binding protein p300
EPHA1 EPH receptor A1
EPHA3 EPH receptor A3
EPO erythropoietin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
F2RL3 coagulation factor II (thrombin) receptor-like 3
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGF2 fibroblast growth factor 2 (basic)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOSL1 FOS-like antigen 1
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXJ3 forkhead box J3
FOXK1 forkhead box K1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FUZ fuzzy planar cell polarity protein
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADD45B growth arrest and DNA-damage-inducible, beta
GBX2 gastrulation brain homeobox 2
GDF15 growth differentiation factor 15
GDF2 growth differentiation factor 2
GDF9 growth differentiation factor 9
GHRHR growth hormone releasing hormone receptor
GIPC1 GIPC PDZ domain containing family, member 1
GLI1 GLI family zinc finger 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNAS GNAS complex locus
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GRN granulin
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HAVCR2 hepatitis A virus cellular receptor 2
HDGF hepatoma-derived growth factor
HEXIM1 hexamethylene bis-acetamide inducible 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGA2 high mobility group AT-hook 2
HMGN5 high mobility group nucleosome binding domain 5
HMOX1 heme oxygenase 1
HOXA13 homeobox A13
HOXC8 homeobox C8
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA14 heat shock 70kDa protein 14
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP1 insulin-like growth factor binding protein 1
IL10 interleukin 10
IL17RC interleukin 17 receptor C
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
ILK integrin-linked kinase
ING2 inhibitor of growth family, member 2
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRF9 interferon regulatory factor 9
JAG1 jagged 1
KAT2B K(lysine) acetyltransferase 2B
KDM1A lysine (K)-specific demethylase 1A
KDM6A lysine (K)-specific demethylase 6A
KDM6B lysine (K)-specific demethylase 6B
KLF5 Kruppel-like factor 5 (intestinal)
KLK3 kallikrein-related peptidase 3
KLK4 kallikrein-related peptidase 4
LCN2 lipocalin 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDHB lactate dehydrogenase B
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS8 lectin, galactoside-binding, soluble, 8
LMO2 LIM domain only 2 (rhombotin-like 1)
LONP1 lon peptidase 1, mitochondrial
LPAR1 lysophosphatidic acid receptor 1
LPP LIM domain containing preferred translocation partner in lipoma
LRRC4 leucine rich repeat containing 4
MAOA monoamine oxidase A
MAPK3 mitogen-activated protein kinase 3
MCAM melanoma cell adhesion molecule
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED15 mediator complex subunit 15
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MS4A8 membrane-spanning 4-domains, subfamily A, member 8
MSMB microseminoprotein, beta-
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC6 mucin 6, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO6 myosin VI
NANOG Nanog homeobox
NCOA3 nuclear receptor coactivator 3
NCOA4 nuclear receptor coactivator 4
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEU3 sialidase 3 (membrane sialidase)
NFE2L2 nuclear factor, erythroid 2-like 2
NLK nemo-like kinase
NME1 NME/NM23 nucleoside diphosphate kinase 1
NNMT nicotinamide N-methyltransferase
NOTCH1 notch 1
NPEPPS aminopeptidase puromycin sensitive
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRBP1 nuclear receptor binding protein 1
NSD2 nuclear receptor binding SET domain protein 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OLFM4 olfactomedin 4
OSCP1 organic solute carrier partner 1
OSM oncostatin M
PADI2 peptidyl arginine deiminase, type II
PARVB parvin, beta
PCNA proliferating cell nuclear antigen
PCSK6 proprotein convertase subtilisin/kexin type 6
PDF peptide deformylase (mitochondrial)
PDGFD platelet derived growth factor D
PDIK1L PDLIM1 interacting kinase 1 like
PEBP1 phosphatidylethanolamine binding protein 1
PEG10 paternally expressed 10
PHF21B PHD finger protein 21B
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLAG1 pleiomorphic adenoma gene 1
PLAU plasminogen activator, urokinase
PLG plasminogen
POSTN periostin, osteoblast specific factor
PRAP1 proline-rich acidic protein 1
PRKD1 protein kinase D1
PROS1 protein S (alpha)
PRR11 proline rich 11
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
PSCA prostate stem cell antigen
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
PTOV1 prostate tumor overexpressed 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPRR protein tyrosine phosphatase, receptor type, R
PXDN peroxidasin
PYCARD PYD and CARD domain containing
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REPS2 RALBP1 associated Eps domain containing 2
RHPN2 rhophilin, Rho GTPase binding protein 2
RMC1 regulator of MON1-CCZ1
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RXFP1 relaxin/insulin-like family peptide receptor 1
S100A4 S100 calcium binding protein A4
SDK1 sidekick cell adhesion molecule 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SENP1 SUMO1/sentrin specific peptidase 1
SERTAD1 SERTA domain containing 1
SGSM3 small G protein signaling modulator 3
SKA1 spindle and kinetochore associated complex subunit 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A9 solute carrier family 39, member 9
SMAD3 SMAD family member 3
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOCS2 suppressor of cytokine signaling 2
SOD3 superoxide dismutase 3, extracellular
SOX2 SRY (sex determining region Y)-box 2
SOX5 SRY (sex determining region Y)-box 5
SPINK1 serine peptidase inhibitor, Kazal type 1
SPOP speckle-type POZ protein
SPP1 secreted phosphoprotein 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SREBF1 sterol regulatory element binding transcription factor 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STS steroid sulfatase (microsomal), isozyme S
SUN2 Sad1 and UNC84 domain containing 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TEP1 telomerase-associated protein 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF3 trefoil factor 3 (intestinal)
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGIF2LX TGFB-induced factor homeobox 2-like, X-linked
TGM2 transglutaminase 2
TM7SF2 transmembrane 7 superfamily member 2
TMEM64 transmembrane protein 64
TMPRSS2 transmembrane protease, serine 2
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNK2 tyrosine kinase, non-receptor, 2
TP53 tumor protein p53
TRAM1 translocation associated membrane protein 1
TRIM37 tripartite motif containing 37
TRIM44 tripartite motif containing 44
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSPAN13 tetraspanin 13
TTK TTK protein kinase
TUG1 taurine up-regulated 1 (non-protein coding)
TWIST1 twist family bHLH transcription factor 1
TYRP1 tyrosinase-related protein 1
UBA7 ubiquitin-like modifier activating enzyme 7
USP12 ubiquitin specific peptidase 12
VAV3 vav 3 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VIP vasoactive intestinal peptide
WDR20 WD repeat domain 20
WDR48 WD repeat domain 48
WNT11 wingless-type MMTV integration site family, member 11
WNT5A wingless-type MMTV integration site family, member 5A
WWTR1 WW domain containing transcription regulator 1
YBX1 Y box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZEB1 zinc finger E-box binding homeobox 1
ZFX zinc finger protein, X-linked
ZNF185 zinc finger protein 185 (LIM domain)