Progressive Cgvhd Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C3539781
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Genes

340 genes associated with the disease Progressive Cgvhd in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTN4 actinin, alpha 4
ADAM17 ADAM metallopeptidase domain 17
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AFP alpha-fetoprotein
AGR2 anterior gradient 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALK anaplastic lymphoma receptor tyrosine kinase
ALLC allantoicase
ALMS1 Alstrom syndrome protein 1
ANGPT2 angiopoietin 2
ANKRD36B ankyrin repeat domain 36B
APCS amyloid P component, serum
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
AREG amphiregulin
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARR3 arrestin 3, retinal (X-arrestin)
ARRB1 arrestin, beta 1
ATF7IP activating transcription factor 7 interacting protein
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATXN1 ataxin 1
AVP arginine vasopressin
AZIN2 antizyme inhibitor 2
B2M beta-2-microglobulin
BACE1 beta-site APP-cleaving enzyme 1
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BID BH3 interacting domain death agonist
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCA calcitonin-related polypeptide alpha
CASR calcium-sensing receptor
CCDC54 coiled-coil domain containing 54
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CD1B CD1b molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD38 CD38 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDA cytidine deaminase
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CENPC centromere protein C
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR5 complement factor H-related 5
CH25H cholesterol 25-hydroxylase
CHGA chromogranin A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHPT1 choline phosphotransferase 1
COX2
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXADR coxsackie virus and adenovirus receptor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYCS cytochrome c, somatic
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCX doublecortin
DDT D-dopachrome tautomerase
DHDDS dehydrodolichyl diphosphate synthase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLL4 delta-like 4 (Drosophila)
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSC3 desmocollin 3
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELN elastin
ENO1 enolase 1, (alpha)
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
ESR1 estrogen receptor 1
F2 coagulation factor II (thrombin)
FBN1 fibrillin 1
FBXW11 F-box and WD repeat domain containing 11
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCMR Fc fragment of IgM receptor
FES FES proto-oncogene, tyrosine kinase
FEV FEV (ETS oncogene family)
FGF23 fibroblast growth factor 23
FGFR3 fibroblast growth factor receptor 3
FHIT fragile histidine triad
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FXN frataxin
GADL1 glutamate decarboxylase-like 1
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
GFAP glial fibrillary acidic protein
GGT1 gamma-glutamyltransferase 1
GGTLC3 gamma-glutamyltransferase light chain 3
GINS2 GINS complex subunit 2 (Psf2 homolog)
GLA galactosidase, alpha
GLI1 GLI family zinc finger 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GP2 glycoprotein 2 (zymogen granule membrane)
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRN granulin
GSTP1 glutathione S-transferase pi 1
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HBB hemoglobin, beta
HDAC4 histone deacetylase 4
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HPR haptoglobin-related protein
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGF1R insulin-like growth factor 1 receptor
IGH immunoglobulin heavy locus
IL10 interleukin 10
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL32 interleukin 32
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
ING4 inhibitor of growth family, member 4
IRF1 interferon regulatory factor 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KDR kinase insert domain receptor
KITLG KIT ligand
KLF2 Kruppel-like factor 2
KLK3 kallikrein-related peptidase 3
KLK6 kallikrein-related peptidase 6
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT10 keratin 10, type I
KRT20 keratin 20, type I
LAG3 lymphocyte-activation gene 3
LBR lamin B receptor
LCN2 lipocalin 2
LEP leptin
LEPR leptin receptor
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
MAP2K7 mitogen-activated protein kinase kinase 7
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCL1 myeloid cell leukemia 1
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2C myocyte enhancer factor 2C
MEFV Mediterranean fever
MIA melanoma inhibitory activity
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSLN mesothelin
MTX1 metaxin 1
MUC1 mucin 1, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOM2 myomesin 2
NANOS2 nanos homolog 2 (Drosophila)
NCAM1 neural cell adhesion molecule 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NLRP1 NLR family, pyrin domain containing 1
NLRP5 NLR family, pyrin domain containing 5
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1I3 nuclear receptor subfamily 1, group I, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OSM oncostatin M
PAH phenylalanine hydroxylase
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPN podoplanin
PECAM1 platelet/endothelial cell adhesion molecule 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLCE1 phospholipase C, epsilon 1
PLP1 proteolipid protein 1
PMP22 peripheral myelin protein 22
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNPLA3 patatin-like phospholipase domain containing 3
POMC proopiomelanocortin
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRDX5 peroxiredoxin 5
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRL prolactin
PROM1 prominin 1
PSEN1 presenilin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRC protein tyrosine phosphatase, receptor type, C
RAD51 RAD51 recombinase
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBBP8 retinoblastoma binding protein 8
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RET ret proto-oncogene
RIPK3 receptor-interacting serine-threonine kinase 3
ROR1 receptor tyrosine kinase-like orphan receptor 1
RTEL1 regulator of telomere elongation helicase 1
S100A14 S100 calcium binding protein A14
S100A7A S100 calcium binding protein A7A
S100B S100 calcium binding protein B
SCO2 SCO2 cytochrome c oxidase assembly protein
SCT secretin
SDC1 syndecan 1
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SELE selectin E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD2 SET domain containing 2
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFTPD surfactant protein D
SH3BP4 SH3-domain binding protein 4
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOD1 superoxide dismutase 1, soluble
SPA17 sperm autoantigenic protein 17
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SST somatostatin
SSTR2 somatostatin receptor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STMN1 stathmin 1
STS steroid sulfatase (microsomal), isozyme S
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBX5 T-box 5
TEK TEK tyrosine kinase, endothelial
TENM1 teneurin transmembrane protein 1
TENM2 teneurin transmembrane protein 2
TF transferrin
TG thyroglobulin
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TH tyrosine hydroxylase
TIMELESS timeless circadian clock
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TIMP2 TIMP metallopeptidase inhibitor 2
TK1 thymidine kinase 1, soluble
TLR1 toll-like receptor 1
TNF tumor necrosis factor
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TP53 tumor protein p53
TPI1 triosephosphate isomerase 1
TPM3 tropomyosin 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM13 tripartite motif containing 13
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPO translocator protein (18kDa)
TTR transthyretin
TUBB4A tubulin, beta 4A class IVa
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
TYR tyrosinase
UBE2B ubiquitin-conjugating enzyme E2B
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VSIR V-set immunoregulatory receptor
VWF von Willebrand factor
WIF1 WNT inhibitory factor 1
WIPF3 WAS/WASL interacting protein family, member 3
WNT5A wingless-type MMTV integration site family, member 5A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZAR1 zygote arrest 1
ZFP36 ZFP36 ring finger protein
ZNF654 zinc finger protein 654