Prolapsed Lumbar Disc Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0281899
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Genes

68 genes associated with the disease Prolapsed Lumbar Disc in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ACAN aggrecan
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMH anti-Mullerian hormone
APRT adenine phosphoribosyltransferase
ASIC3 acid sensing (proton gated) ion channel 3
BDNF brain-derived neurotrophic factor
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDKN2A cyclin-dependent kinase inhibitor 2A
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
COL11A1 collagen, type XI, alpha 1
COMT catechol-O-methyltransferase
COX2
CXCL8 chemokine (C-X-C motif) ligand 8
ELN elastin
EYS eyes shut homolog (Drosophila)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FBN2 fibrillin 2
FGF1 fibroblast growth factor 1 (acidic)
FTH1 ferritin, heavy polypeptide 1
GAP43 growth associated protein 43
GDF5 growth differentiation factor 5
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL33 interleukin 33
IL37 interleukin 37
IL6 interleukin 6
KIAA1217 KIAA1217
LIF leukemia inhibitory factor
MARCHF1 membrane associated ring-CH-type finger 1
MFAP1 microfibrillar-associated protein 1
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MOK MOK protein kinase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NGF nerve growth factor (beta polypeptide)
OPRM1 opioid receptor, mu 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STOX1 storkhead box 1
THBS2 thrombospondin 2
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor