Proliferative Diabetic Retinopathy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0154830
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Genes

170 genes associated with the disease Proliferative Diabetic Retinopathy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACE angiotensin I converting enzyme
ADM adrenomedullin
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AMD1 adenosylmethionine decarboxylase 1
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPTL4 angiopoietin-like 4
ANGPTL8 angiopoietin like 8
AOC2 amine oxidase, copper containing 2 (retina-specific)
AOC3 amine oxidase, copper containing 3
APLN apelin
APLNR apelin receptor
APOE apolipoprotein E
ATF4 activating transcription factor 4
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BSG basigin (Ok blood group)
C1ORF94 chromosome 1 open reading frame 94
C1ORF95 chromosome 1 open reading frame 95
C1QTNF3 C1q and tumor necrosis factor related protein 3
C1QTNF5 C1q and tumor necrosis factor related protein 5
C5 complement component 5
CAPN5 calpain 5
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CD200 CD200 molecule
CD44 CD44 molecule (Indian blood group)
CD96 CD96 molecule
CEP135 centrosomal protein 135kDa
CNTF ciliary neurotrophic factor
COMMD1 copper metabolism (Murr1) domain containing 1
CPM carboxypeptidase M
CTSH cathepsin H
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DPEP1 dipeptidase 1 (renal)
DPP10 dipeptidyl-peptidase 10 (non-functional)
EDN1 endothelin 1
EFNB2 ephrin-B2
ENHO energy homeostasis associated
ENO2 enolase 2 (gamma, neuronal)
EPO erythropoietin
ERBB3 erb-b2 receptor tyrosine kinase 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV5 ets variant 5
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
GDNF glial cell derived neurotrophic factor
GFAP glial fibrillary acidic protein
GFER growth factor, augmenter of liver regeneration
GH1 growth hormone 1
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPATCH2 G patch domain containing 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HP haptoglobin
HPSE heparanase
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL11 interleukin 11
IL11RA interleukin 11 receptor, alpha
IL13 interleukin 13
IL17D interleukin 17D
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL26 interleukin 26
IL27 interleukin 27
IL31 interleukin 31
IL6 interleukin 6
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDR kinase insert domain receptor
KMT2D lysine (K)-specific methyltransferase 2D
LGALS1 lectin, galactoside-binding, soluble, 1
LOX lysyl oxidase
LTA lymphotoxin alpha
MFRP membrane frizzled-related protein
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2
NELFE negative elongation factor complex member E
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NPY neuropeptide Y
NPY2R neuropeptide Y receptor Y2
NRP1 neuropilin 1
OC90 otoconin 90
PEBP1 phosphatidylethanolamine binding protein 1
PFN1 profilin 1
PGF placental growth factor
PIWIL4 piwi-like RNA-mediated gene silencing 4
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLG plasminogen
PLXDC1 plexin domain containing 1
PLXNA2 plexin A2
PML promyelocytic leukemia
PNPLA2 patatin-like phospholipase domain containing 2
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTN pleiotrophin
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RETN resistin
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPE ribulose-5-phosphate-3-epimerase
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SDC1 syndecan 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLIT2 slit homolog 2 (Drosophila)
SNAP47 synaptosomal-associated protein, 47kDa
SORD sorbitol dehydrogenase
SP1 Sp1 transcription factor
SST somatostatin
SYT1 synaptotagmin I
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TIMP3 TIMP metallopeptidase inhibitor 3
TMSB4X thymosin beta 4, X-linked
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAMP8 vesicle-associated membrane protein 8
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VWF von Willebrand factor
WDR72 WD repeat domain 72
WNK1 WNK lysine deficient protein kinase 1
XCR1 chemokine (C motif) receptor 1
ZFP82 ZFP82 zinc finger protein