Propafenone Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias. (Chemical Entities of Biological Interest Ontology, CHEBI_63619)
External Link http://www.hmdb.ca/metabolites/HMDB15313
Similar Terms
Downloads & Tools

Genes

8 interacting proteins for the Propafenone metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
SCN5A sodium channel, voltage gated, type V alpha subunit