Prostate Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A male reproductive organ cancer that is located_in the prostate. (Human Disease Ontology, DOID_10283)
External Link https://www.disgenet.org/browser/0/1/0/C1370962
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Genes

188 genes associated with the disease Prostate Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACP3 acid phosphatase 3
ADGRG1 adhesion G protein-coupled receptor G1
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMACR alpha-methylacyl-CoA racemase
AR androgen receptor
ARHGAP6 Rho GTPase activating protein 6
ARL11 ADP-ribosylation factor-like 11
ATAT1 alpha tubulin acetyltransferase 1
ATM ATM serine/threonine kinase
B3GAT1 beta-1,3-glucuronyltransferase 1
BCAS1 breast carcinoma amplified sequence 1
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BGLAP bone gamma-carboxyglutamate (gla) protein
BGN biglycan
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CASC5 cancer susceptibility candidate 5
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAVIN1 caveolae associated protein 1
CBX4 chromobox homolog 4
CCL2 chemokine (C-C motif) ligand 2
CDCA7 cell division cycle associated 7
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CENPF centromere protein F, 350/400kDa
CHD3 chromodomain helicase DNA binding protein 3
CHEK2 checkpoint kinase 2
COL23A1 collagen, type XXIII, alpha 1
CPA4 carboxypeptidase A4
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CT55 cancer/testis antigen 55
CXCL8 chemokine (C-X-C motif) ligand 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DENND4B DENN/MADD domain containing 4B
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK2 dedicator of cytokinesis 2
DSG2 desmoglein 2
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EHBP1 EH domain binding protein 1
ELAC2 elaC ribonuclease Z 2
EMSY EMSY transcriptional repressor, BRCA2 interacting
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERCC1 excision repair cross-complementation group 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV1 ets variant 1
ETV4 ets variant 4
FAM13C family with sequence similarity 13, member C
FBRSL1 fibrosin-like 1
FECH ferrochelatase
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXA1 forkhead box A1
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
GATA2 GATA binding protein 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLIPR1 GLI pathogenesis-related 1
GRPR gastrin-releasing peptide receptor
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAUS6 HAUS augmin-like complex, subunit 6
HDAC9 histone deacetylase 9
HES6 hes family bHLH transcription factor 6
HLA-DOA major histocompatibility complex, class II, DO alpha
HNF1B HNF1 homeobox B
HOXB13 homeobox B13
HPN hepsin
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL6 interleukin 6
INCENP inner centromere protein antigens 135/155kDa
ITGB8 integrin, beta 8
KDM2A lysine (K)-specific demethylase 2A
KIF11 kinesin family member 11
KLF6 Kruppel-like factor 6
KLK15 kallikrein-related peptidase 15
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
LARP4B La ribonucleoprotein domain family, member 4B
LGALS8 lectin, galactoside-binding, soluble, 8
LMNA lamin A/C
LZTS1 leucine zipper, putative tumor suppressor 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGEA11 melanoma antigen family A11
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MBD2 methyl-CpG binding domain protein 2
MBNL1 muscleblind-like splicing regulator 1
MECOM MDS1 and EVI1 complex locus
MGLL monoglyceride lipase
MLH1 mutL homolog 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MOB2 MOB kinase activator 2
MSMB microseminoprotein, beta-
MSR1 macrophage scavenger receptor 1
MT-ATP6 ATP synthase F0 subunit 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO9B myosin IXB
NBN nibrin
NKX3-1 NK3 homeobox 1
NPEPPS aminopeptidase puromycin sensitive
NUSAP1 nucleolar and spindle associated protein 1
ODC1 ornithine decarboxylase 1
PALB2 partner and localizer of BRCA2
PAX9 paired box 9
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PITX2 paired-like homeodomain 2
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKNOX2 PBX/knotted 1 homeobox 2
PLAG1 pleiomorphic adenoma gene 1
PON1 paraoxonase 1
POU2F2 POU class 2 homeobox 2
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PROS1 protein S (alpha)
PSAT1 phosphoserine aminotransferase 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASA2 RAS p21 protein activator 2
RASSF3 Ras association (RalGDS/AF-6) domain family member 3
RFX7 regulatory factor X, 7
RGS8 regulator of G-protein signaling 8
RGSL1 regulator of G-protein signaling like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF43 ring finger protein 43
RNLS renalase, FAD-dependent amine oxidase
RUNX2 runt-related transcription factor 2
SATB1 SATB homeobox 1
SENP1 SUMO1/sentrin specific peptidase 1
SFRP4 secreted frizzled-related protein 4
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SPOP speckle-type POZ protein
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SUGCT succinyl-CoA:glutarate-CoA transferase
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TBX21 T-box 21
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
THOC1 THO complex 1
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TSHZ1 teashirt zinc finger homeobox 1
TTC28 tetratricopeptide repeat domain 28
UHRF1BP1 UHRF1 binding protein 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZFHX3 zinc finger homeobox 3