Prostate cancer Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
Description A male reproductive organ cancer that is located_in the prostate. (Human Disease Ontology, DOID_10283)
External Link https://www.kegg.jp/entry/hsa05215
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Genes

103 proteins participating in the Prostate cancer pathway from the KEGG Pathways 2026 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ARAF A-Raf proto-oncogene, serine/threonine kinase
AREG amphiregulin
ATF4 activating transcription factor 4
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CCNE1 cyclin E1
CCNE2 cyclin E2
CDK2 cyclin-dependent kinase 2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDPF1 cysteine-rich, DPF motif domain containing 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLSTN1 calsyntenin 1
CREB1 cAMP responsive element binding protein 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CREB3L3 cAMP responsive element binding protein 3-like 3
CREB3L4 cAMP responsive element binding protein 3-like 4
CREB5 cAMP responsive element binding protein 5
CREBBP CREB binding protein
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ETV5 ets variant 5
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLR2 folate receptor 2 (fetal)
FOLR3 folate receptor 3 (gamma)
FOXO1 forkhead box O1
GRB2 growth factor receptor-bound protein 2
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1R2 interleukin 1 receptor, type II
INS insulin
INSRR insulin receptor-related receptor
KLKB1 kallikrein B, plasma (Fletcher factor) 1
LEF1 lymphoid enhancer-binding factor 1
LNCEGFL7OS lncRNA EGFL7 opposite strand
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX3-1 NK3 homeobox 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PTEN phosphatase and tensin homolog
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNASE3 ribonuclease, RNase A family, 3
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC46A1 solute carrier family 46 (folate transporter), member 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SPINT1 serine peptidase inhibitor, Kunitz type 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFA transforming growth factor, alpha
TMPRSS2 transmembrane protease, serine 2
TP53 tumor protein p53
ZEB1 zinc finger E-box binding homeobox 1