Prostatic Intraepithelial Neoplasias Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0282612
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Genes

220 genes associated with the disease Prostatic Intraepithelial Neoplasias in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AGR2 anterior gradient 2
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALKBH3 alkB, alkylation repair homolog 3 (E. coli)
ALOX12 arachidonate 12-lipoxygenase
ALOX15 arachidonate 15-lipoxygenase
AMACR alpha-methylacyl-CoA racemase
ANG angiogenin, ribonuclease, RNase A family, 5
ANXA1 annexin A1
ANXA2 annexin A2
APRT adenine phosphoribosyltransferase
AR androgen receptor
AREG amphiregulin
ARRB2 arrestin, beta 2
ATF3 activating transcription factor 3
AURKA aurora kinase A
BCL2 B-cell CLL/lymphoma 2
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMX BMX non-receptor tyrosine kinase
CAV1 caveolin 1, caveolae protein, 22kDa
CBX4 chromobox homolog 4
CCND1 cyclin D1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHKA choline kinase alpha
CIB1 calcium and integrin binding 1 (calmyrin)
CLCA2 chloride channel accessory 2
CLDN3 claudin 3
CLU clusterin
COX2
CREB3L4 cAMP responsive element binding protein 3-like 4
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSK cathepsin K
CTSZ cathepsin Z
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCTN6 dynactin 6
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPT dermatopontin
DRG1 developmentally regulated GTP binding protein 1
DUSP1 dual specificity phosphatase 1
DYNLL1 dynein, light chain, LC8-type 1
EAF1 ELL associated factor 1
EAF2 ELL associated factor 2
EGFR epidermal growth factor receptor
ELAC2 elaC ribonuclease Z 2
ELL2 elongation factor, RNA polymerase II, 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV1 ets variant 1
EZR ezrin
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAS Fas cell surface death receptor
FASN fatty acid synthase
FGF10 fibroblast growth factor 10
FLT1 fms-related tyrosine kinase 1
FOXA1 forkhead box A1
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GDF15 growth differentiation factor 15
GLIPR1 GLI pathogenesis-related 1
GORASP1 golgi reassembly stacking protein 1, 65kDa
GRN granulin
GSTA1 glutathione S-transferase alpha 1
GSTP1 glutathione S-transferase pi 1
HDAC1 histone deacetylase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIC1 hypermethylated in cancer 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HOXB13 homeobox B13
HPGDS hematopoietic prostaglandin D synthase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IFI27 interferon, alpha-inducible protein 27
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL27 interleukin 27
INSL3 insulin-like 3 (Leydig cell)
IQGAP2 IQ motif containing GTPase activating protein 2
IRS2 insulin receptor substrate 2
KDM4A lysine (K)-specific demethylase 4A
KLF4 Kruppel-like factor 4 (gut)
KLK15 kallikrein-related peptidase 15
KLK3 kallikrein-related peptidase 3
KLK4 kallikrein-related peptidase 4
KRT14 keratin 14, type I
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMNA lamin A/C
LOC105371045 uncharacterized LOC105371045
LONP1 lon peptidase 1, mitochondrial
MAN2C1 mannosidase, alpha, class 2C, member 1
MCM7 minichromosome maintenance complex component 7
MET MET proto-oncogene, receptor tyrosine kinase
MFAP1 microfibrillar-associated protein 1
MGMT O-6-methylguanine-DNA methyltransferase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MKI67 marker of proliferation Ki-67
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP26 matrix metallopeptidase 26
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MOK MOK protein kinase
MRC1 mannose receptor, C type 1
MT2A metallothionein 2A
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO1C myosin IC
MYO1E myosin IE
NDRG1 N-myc downstream regulated 1
NEFL neurofilament, light polypeptide
NME1 NME/NM23 nucleoside diphosphate kinase 1
NPEPPS aminopeptidase puromycin sensitive
NR2C2 nuclear receptor subfamily 2, group C, member 2
OLFM4 olfactomedin 4
OPRD1 opioid receptor, delta 1
OR51E1 olfactory receptor, family 51, subfamily E, member 1
OR51E2 olfactory receptor, family 51, subfamily E, member 2
PARD3 par-3 family cell polarity regulator
PDZD2 PDZ domain containing 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PITX2 paired-like homeodomain 2
PLAG1 pleiomorphic adenoma gene 1
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLK1 polo-like kinase 1
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNN pinin, desmosome associated protein
PROS1 protein S (alpha)
PSAT1 phosphoserine aminotransferase 1
PSCA prostate stem cell antigen
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTMA prothymosin, alpha
PTOV1 prostate tumor overexpressed 1
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic)
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RARB retinoic acid receptor, beta
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RXRA retinoid X receptor, alpha
S100A1 S100 calcium binding protein A1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SAT2 spermidine/spermine N1-acetyltransferase family member 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SENP1 SUMO1/sentrin specific peptidase 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SET SET nuclear proto-oncogene
SETD2 SET domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SIRT1 sirtuin 1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMAD2 SMAD family member 2
SMOX spermine oxidase
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
SRPX sushi-repeat containing protein, X-linked
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TGFB2 transforming growth factor, beta 2
TICAM2 toll-like receptor adaptor molecule 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP4 TIMP metallopeptidase inhibitor 4
TLR5 toll-like receptor 5
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMPRSS2 transmembrane protease, serine 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNRC6A trinucleotide repeat containing 6A
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP63 tumor protein p63
TRAM1 translocation associated membrane protein 1
TRAP1 TNF receptor-associated protein 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN13 tetraspanin 13
TSPO translocator protein (18kDa)
TWIST2 twist family bHLH transcription factor 2
VEGFA vascular endothelial growth factor A
VIM vimentin
VTA1 vesicle (multivesicular body) trafficking 1
WNK1 WNK lysine deficient protein kinase 1
WNT10B wingless-type MMTV integration site family, member 10B
ZBED1 zinc finger, BED-type containing 1