Prostatitis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment. (Experimental Factor Ontology, EFO_0003830)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D011472
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Genes

249 genes/proteins associated with the disease Prostatitis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
IL10 interleukin 10 2.88009
IGF1R insulin-like growth factor 1 receptor 1.60058
CYP3A cytochrome P450, family 3, subfamily A 1.59241
AR androgen receptor 1.57498
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.57426
PRLR prolactin receptor 1.53308
SFN stratifin 1.46568
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.43673
CCND1 cyclin D1 1.41938
FADD Fas (TNFRSF6)-associated via death domain 1.40232
GHR growth hormone receptor 1.39674
HMGB2 high mobility group box 2 1.38946
ODC1 ornithine decarboxylase 1 1.38584
FOS FBJ murine osteosarcoma viral oncogene homolog 1.37733
TIMP3 TIMP metallopeptidase inhibitor 3 1.34111
RARA retinoic acid receptor, alpha 1.33701
PGR progesterone receptor 1.33612
CAT catalase 1.32577
CFLAR CASP8 and FADD-like apoptosis regulator 1.32577
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.32458
COL3A1 collagen, type III, alpha 1 1.31776
TGFB2 transforming growth factor, beta 2 1.31506
MED11 mediator complex subunit 11 1.3103
SMTNL2 smoothelin-like 2 1.3103
GADD45A growth arrest and DNA-damage-inducible, alpha 1.30788
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.3039
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.30056
CCNB1 cyclin B1 1.29626
ECE1 endothelin converting enzyme 1 1.28765
TUBB6 tubulin, beta 6 class V 1.28272
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 1.27782
PLAU plasminogen activator, urokinase 1.27595
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.27564
PARP12 poly (ADP-ribose) polymerase family, member 12 1.27286
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.27101
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.26947
NRIP1 nuclear receptor interacting protein 1 1.26638
IL1B interleukin 1, beta 1.26421
EDN1 endothelin 1 1.26298
ESR1 estrogen receptor 1 1.26267
NUP107 nucleoporin 107kDa 1.26021
IGF1 insulin-like growth factor 1 (somatomedin C) 1.25745
HDAC8 histone deacetylase 8 1.25432
GAL galanin/GMAP prepropeptide 1.25307
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 1.2509
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.2456
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.24496
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.24275
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.24244
EGFR epidermal growth factor receptor 1.2415
STAT1 signal transducer and activator of transcription 1, 91kDa 1.23775
FGF2 fibroblast growth factor 2 (basic) 1.23488
MCL1 myeloid cell leukemia 1 1.23106
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.22884
PARP9 poly (ADP-ribose) polymerase family, member 9 1.22664
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.22534
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.22339
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.22177
MYH14 myosin, heavy chain 14, non-muscle 1.21663
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.21567
LHB luteinizing hormone beta polypeptide 1.21108
CXCL10 chemokine (C-X-C motif) ligand 10 1.21108
CCNE1 cyclin E1 1.20751
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 1.20719
ACTA2 actin, alpha 2, smooth muscle, aorta 1.20654
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.2059
BCL2L1 BCL2-like 1 1.2046
EGF epidermal growth factor 1.20229
MSMO1 methylsterol monooxygenase 1 1.19999
NMI N-myc (and STAT) interactor 1.19802
GSTP1 glutathione S-transferase pi 1 1.1977
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.19509
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 1.19412
GPATCH4 G patch domain containing 4 1.19412
CDK2 cyclin-dependent kinase 2 1.19246
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.19047
AQP1 aquaporin 1 (Colton blood group) 1.18849
KLK3 kallikrein-related peptidase 3 1.18751
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.18587
FGD4 FYVE, RhoGEF and PH domain containing 4 1.18521
BDNF brain-derived neurotrophic factor 1.18026
BAX BCL2-associated X protein 1.17794
GADD45G growth arrest and DNA-damage-inducible, gamma 1.17761
PDGFA platelet-derived growth factor alpha polypeptide 1.17629
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.17497
JUND jun D proto-oncogene 1.17333
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.17202
ANGPTL2 angiopoietin-like 2 1.16967
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.16766
CPEB2 cytoplasmic polyadenylation element binding protein 2 1.16633
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.166
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.166
GSK3B glycogen synthase kinase 3 beta 1.16368
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.16368
PRKD1 protein kinase D1 1.16302
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.16302
RAD51 RAD51 recombinase 1.16137
TSPAN8 tetraspanin 8 1.15933
TP53 tumor protein p53 1.15865
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.15763
TGFB1 transforming growth factor, beta 1 1.15729
HPCAL1 hippocalcin-like 1 1.15256
TRPV6 transient receptor potential cation channel, subfamily V, member 6 1.15223
HSDL2 hydroxysteroid dehydrogenase like 2 1.14885
TNS3 tensin 3 1.14885
IRS1 insulin receptor substrate 1 1.14507
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.14473
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.14438
IGF2 insulin-like growth factor 2 1.1437
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.142
FSHR follicle stimulating hormone receptor 1.1403
HIST1H2BO histone cluster 1, H2bo 1.1403
AHR aryl hydrocarbon receptor 1.13997
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 1.13862
BRCA1 breast cancer 1, early onset 1.13586
VEGFA vascular endothelial growth factor A 1.13484
JUN jun proto-oncogene 1.13449
COL1A1 collagen, type I, alpha 1 1.13347
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.13347
STAT2 signal transducer and activator of transcription 2, 113kDa 1.12634
CXCR4 chemokine (C-X-C motif) receptor 4 1.12599
CCND2 cyclin D2 1.12495
TFF1 trefoil factor 1 1.12461
TES testin LIM domain protein 1.12357
HDAC2 histone deacetylase 2 1.12117
DST dystonin 1.12048
PCNA proliferating cell nuclear antigen 1.11911
FOXA1 forkhead box A1 1.11809
ESR2 estrogen receptor 2 (ER beta) 1.11501
EGR1 early growth response 1 1.1129
PLSCR1 phospholipid scramblase 1 1.1122
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.1122
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 1.10665
TNF tumor necrosis factor 1.10631
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.10596
IFNG interferon, gamma 1.10562
LMCD1 LIM and cysteine-rich domains 1 1.10493
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.10388
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 1.10246
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 1.09927
IL6 interleukin 6 1.09892
PSRC1 proline/serine-rich coiled-coil 1 1.09857
ANGPT1 angiopoietin 1 1.09681
SDK1 sidekick cell adhesion molecule 1 1.09611
DDIT3 DNA-damage-inducible transcript 3 1.0919
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.0919
TEK TEK tyrosine kinase, endothelial 1.09154
CGA glycoprotein hormones, alpha polypeptide 1.08868
AHNAK AHNAK nucleoprotein 1.08655
BCL3 B-cell CLL/lymphoma 3 1.08619
BIRC3 baculoviral IAP repeat containing 3 1.08549
ARRDC3 arrestin domain containing 3 1.08407
MUC1 mucin 1, cell surface associated 1.08372
PNPLA2 patatin-like phospholipase domain containing 2 1.08372
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.08126
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.08055
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.07875
DBP D site of albumin promoter (albumin D-box) binding protein 1.07732
FSHB follicle stimulating hormone, beta polypeptide 1.07589
LPIN1 lipin 1 1.07234
CEP83 centrosomal protein 83kDa 1.07128
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 1.07128
GSR glutathione reductase 1.07057
CTGF connective tissue growth factor 1.07022
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 1.07022
UBQLN4 ubiquilin 4 1.07022
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.06987
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.06588
TOP2A topoisomerase (DNA) II alpha 170kDa 1.06552
PROM1 prominin 1 1.06515
BAD BCL2-associated agonist of cell death 1.06479
MRPS27 mitochondrial ribosomal protein S27 1.06297
SFPQ splicing factor proline/glutamine-rich 1.06188
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.06152
GJA1 gap junction protein, alpha 1, 43kDa 1.06116
COL18A1 collagen, type XVIII, alpha 1 1.05936
CLU clusterin 1.05936
VIM vimentin 1.059
FASLG Fas ligand (TNF superfamily, member 6) 1.05721
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.05573
HRAS Harvey rat sarcoma viral oncogene homolog 1.05535
SAMD9 sterile alpha motif domain containing 9 1.05498
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.05461
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.05349
SREBF1 sterol regulatory element binding transcription factor 1 1.05312
EFNA1 ephrin-A1 1.05274
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.04868
MMD2 monocyte to macrophage differentiation-associated 2 1.04831
NUP133 nucleoporin 133kDa 1.04794
DGKH diacylglycerol kinase, eta 1.04794
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 1.04757
MIR93 microRNA 93 1.04757
DUSP1 dual specificity phosphatase 1 1.04611
STAR steroidogenic acute regulatory protein 1.04611
FADS1 fatty acid desaturase 1 1.04611
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.04574
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.04501
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.04427
STC2 stanniocalcin 2 1.04427
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 1.04427
SOX9 SRY (sex determining region Y)-box 9 1.04427
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.04276
SENP5 SUMO1/sentrin specific peptidase 5 1.04163
DPF1 D4, zinc and double PHD fingers family 1 1.04126
HMOX1 heme oxygenase 1 1.04088
CDK4 cyclin-dependent kinase 4 1.04088
TH tyrosine hydroxylase 1.04051
PTHLH parathyroid hormone-like hormone 1.04014
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.03901
COL4A1 collagen, type IV, alpha 1 1.03456
IRS2 insulin receptor substrate 2 1.03456
TGFBR1 transforming growth factor, beta receptor 1 1.03419
CLDN1 claudin 1 1.03308
NFIL3 nuclear factor, interleukin 3 regulated 1.03308
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 1.03122
DAPK1 death-associated protein kinase 1 1.03122
P4HB prolyl 4-hydroxylase, beta polypeptide 1.03084
NOS2 nitric oxide synthase 2, inducible 1.03046
GUSB glucuronidase, beta 1.02933
MMP12 matrix metallopeptidase 12 1.02933
LYRM5 LYR motif containing 5 1.02821
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 1.02746
MAPK9 mitogen-activated protein kinase 9 1.02708
JAK1 Janus kinase 1 1.02596
BRCA2 breast cancer 2, early onset 1.02522
CCNA2 cyclin A2 1.02447
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.0241
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 1.02373
THOC1 THO complex 1 1.02262
SNX4 sorting nexin 4 1.02225
PAK1IP1 PAK1 interacting protein 1 1.02225
ADRA1B adrenoceptor alpha 1B 1.02188
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.02151
PNPT1 polyribonucleotide nucleotidyltransferase 1 1.02151
FOXL2 forkhead box L2 1.01928
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 1.01701
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 1.01587
FASTKD2 FAST kinase domains 2 1.01587
MRPL33 mitochondrial ribosomal protein L33 1.01587
CDC25B cell division cycle 25B 1.01512
TGFB3 transforming growth factor, beta 3 1.01512
ATF3 activating transcription factor 3 1.01324
MAPK14 mitogen-activated protein kinase 14 1.01249
CSHL1 chorionic somatomammotropin hormone-like 1 1.01174
FADS2 fatty acid desaturase 2 1.01137
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.01099
FAM110C family with sequence similarity 110, member C 1.01025
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 1.01025
GOLIM4 golgi integral membrane protein 4 1.01025