Proteasome regulatory particle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex. (Gene Ontology, GO_0005838)
External Link http://amigo.geneontology.org/amigo/term/GO:0005838
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Genes

1000 proteins co-occuring with the Proteasome regulatory particle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ADRM1 adhesion regulating molecule 1 3.432
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 3.41
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 3.369
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 3.197
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 3.07
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.974
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 2.959
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 2.945
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 2.937
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.916
PSME4 proteasome (prosome, macropain) activator subunit 4 2.899
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.841
CTRL chymotrypsin-like 2.751
ZUP1 zinc finger containing ubiquitin peptidase 1 2.745
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 2.725
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 2.648
PAAF1 proteasomal ATPase-associated factor 1 2.644
ECPAS Ecm29 proteasome adaptor and scaffold 2.628
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 2.624
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.616
POMP proteasome maturation protein 2.581
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.571
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 2.531
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 2.524
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.477
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 2.47
UBQLN1 ubiquilin 1 2.467
DNAH8 dynein, axonemal, heavy chain 8 2.462
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.379
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) 2.372
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 2.364
UBQLN2 ubiquilin 2 2.362
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.357
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 2.357
VCP valosin containing protein 2.344
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 2.312
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 2.308
SEM1 SEM1 26S proteasome subunit 2.297
COPS5 COP9 signalosome subunit 5 2.288
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11 2.28
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 2.256
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 2.231
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 2.2
UBA1 ubiquitin-like modifier activating enzyme 1 2.162
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 2.162
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 2.119
UBE3A ubiquitin protein ligase E3A 2.096
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 2.077
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 2.07
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 2.066
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.064
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.029
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 2.02
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 2.014
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.008
RAD23A RAD23 homolog A (S. cerevisiae) 2.0
UBE3C ubiquitin protein ligase E3C 1.992
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 1.991
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.989
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.986
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.98
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 1.972
UBE2S ubiquitin-conjugating enzyme E2S 1.972
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.965
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 1.941
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.938
ZFAND2A zinc finger, AN1-type domain 2A 1.918
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 1.917
UFD1 ubiquitin recognition factor in ER associated degradation 1 1.884
TP53 tumor protein p53 1.88
CTRB2 chymotrypsinogen B2 1.872
RAD23B RAD23 homolog B (S. cerevisiae) 1.872
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.87
CTRB1 chymotrypsinogen B1 1.867
UBD ubiquitin D 1.866
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.866
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.859
HSPA4 heat shock 70kDa protein 4 1.85
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 1.836
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 1.831
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 1.825
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.813
SKP1 S-phase kinase-associated protein 1 1.794
NFE2L1 nuclear factor, erythroid 2-like 1 1.791
STAMBP STAM binding protein 1.782
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 1.781
ATXN3 ataxin 3 1.779
STAMBPL1 STAM binding protein-like 1 1.772
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.766
UBA6 ubiquitin-like modifier activating enzyme 6 1.765
CUL1 cullin 1 1.765
ATXN3L ataxin 3-like 1.759
USP9X ubiquitin specific peptidase 9, X-linked 1.753
UBE2K ubiquitin-conjugating enzyme E2K 1.744
USP2 ubiquitin specific peptidase 2 1.744
NFRKB nuclear factor related to kappaB binding protein 1.742
UBE4B ubiquitination factor E4B 1.742
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 1.73
ZFAND5 zinc finger, AN1-type domain 5 1.724
CDC34 cell division cycle 34 1.722
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.719
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 1.718
UBR1 ubiquitin protein ligase E3 component n-recognin 1 1.712
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 1.707
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.703
USP1 ubiquitin specific peptidase 1 1.694
SESN1 sestrin 1 1.691
UBE4A ubiquitination factor E4A 1.686
USP22 ubiquitin specific peptidase 22 1.679
UBQLN4 ubiquilin 4 1.677
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.669
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.65
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1.649
RPL11 ribosomal protein L11 1.643
CUL3 cullin 3 1.64
UBE2N ubiquitin-conjugating enzyme E2N 1.636
USP15 ubiquitin specific peptidase 15 1.634
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.633
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 1.625
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1.623
FLII flightless I homolog (Drosophila) 1.615
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.61
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.606
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.6
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.594
CNOT4 CCR4-NOT transcription complex, subunit 4 1.584
ZFAND2B zinc finger, AN1-type domain 2B 1.545
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.545
ATXN7 ataxin 7 1.54
NGLY1 N-glycanase 1 1.534
USP8 ubiquitin specific peptidase 8 1.532
USP11 ubiquitin specific peptidase 11 1.531
UBE2D1 ubiquitin-conjugating enzyme E2D 1 1.522
DDB1 damage-specific DNA binding protein 1, 127kDa 1.52
UBB ubiquitin B 1.519
IFNG interferon, gamma 1.51
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.51
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.504
UBE2W ubiquitin-conjugating enzyme E2W (putative) 1.503
THRB thyroid hormone receptor, beta 1.502
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.502
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.499
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 1.497
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.496
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 1.495
SQSTM1 sequestosome 1 1.484
UXT ubiquitously-expressed, prefoldin-like chaperone 1.481
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.48
PLEK2 pleckstrin 2 1.478
MARCHF6 membrane associated ring-CH-type finger 6 1.477
H2BC21 H2B clustered histone 21 1.477
WDR48 WD repeat domain 48 1.475
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 1.471
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.47
MPND MPN domain containing 1.469
PLEK pleckstrin 1.468
USP20 ubiquitin specific peptidase 20 1.457
CRBN cereblon 1.451
CYLD cylindromatosis (turban tumor syndrome) 1.445
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.437
CCNL2 cyclin L2 1.436
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.435
USP37 ubiquitin specific peptidase 37 1.432
GABARAPL1 GABA(A) receptor-associated protein like 1 1.428
HSPA8 heat shock 70kDa protein 8 1.421
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.416
GABARAPL2 GABA(A) receptor-associated protein-like 2 1.412
PRKN parkin RBR E3 ubiquitin protein ligase 1.412
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.409
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 1.408
USP28 ubiquitin specific peptidase 28 1.408
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 1.407
UBC ubiquitin C 1.402
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.402
NBR1 neighbor of BRCA1 gene 1 1.399
KEAP1 kelch-like ECH-associated protein 1 1.398
BAG1 BCL2-associated athanogene 1.397
USP24 ubiquitin specific peptidase 24 1.394
USP47 ubiquitin specific peptidase 47 1.389
FBXO32 F-box protein 32 1.383
H2AC19 H2A clustered histone 19 1.38
HDAC6 histone deacetylase 6 1.376
ATG5 autophagy related 5 1.375
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.374
H2AC20 H2A clustered histone 20 1.373
ULK1 unc-51 like autophagy activating kinase 1 1.37
UBA7 ubiquitin-like modifier activating enzyme 7 1.37
AREG amphiregulin 1.369
COPS6 COP9 signalosome subunit 6 1.366
UBE2C ubiquitin-conjugating enzyme E2C 1.365
MCL1 myeloid cell leukemia 1 1.364
BCL2 B-cell CLL/lymphoma 2 1.364
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.362
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.359
MYSM1 Myb-like, SWIRM and MPN domains 1 1.358
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 1.357
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.357
XPC xeroderma pigmentosum, complementation group C 1.345
ZRANB1 zinc finger, RAN-binding domain containing 1 1.344
TNF tumor necrosis factor 1.342
GZMM granzyme M (lymphocyte met-ase 1) 1.34
NUB1 negative regulator of ubiquitin-like proteins 1 1.336
TBX22 T-box 22 1.335
USP19 ubiquitin specific peptidase 19 1.333
USP3 ubiquitin specific peptidase 3 1.328
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.323
USP12 ubiquitin specific peptidase 12 1.319
LGALS4 lectin, galactoside-binding, soluble, 4 1.317
H3C7 H3 clustered histone 7 1.317
CUL4B cullin 4B 1.316
UBR2 ubiquitin protein ligase E3 component n-recognin 2 1.314
UBQLNL ubiquilin-like 1.312
UBE2B ubiquitin-conjugating enzyme E2B 1.311
WWP1 WW domain containing E3 ubiquitin protein ligase 1 1.31
BECN1 beclin 1, autophagy related 1.31
RNF31 ring finger protein 31 1.305
EIF3F eukaryotic translation initiation factor 3, subunit F 1.303
H3-7 H3.7 histone (putative) 1.302
H3C13 H3 clustered histone 13 1.302
H3-5 H3.5 histone 1.301
H3-4 H3.4 histone, cluster member 1.301
ATG12 autophagy related 12 1.299
PRKCA protein kinase C, alpha 1.299
H3-3B H3.3 histone B 1.298
ATG7 autophagy related 7 1.297
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 1.293
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.291
UBQLN3 ubiquilin 3 1.289
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.288
TARDBP TAR DNA binding protein 1.288
PARP1 poly (ADP-ribose) polymerase 1 1.287
BRCA1 breast cancer 1, early onset 1.287
SYVN1 synovial apoptosis inhibitor 1, synoviolin 1.285
POTEF POTE ankyrin domain family, member F 1.283
FOXO4 forkhead box O4 1.28
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.279
USP44 ubiquitin specific peptidase 44 1.277
CUL4A cullin 4A 1.273
ITCH itchy E3 ubiquitin protein ligase 1.271
ENY2 enhancer of yellow 2 homolog (Drosophila) 1.271
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.268
TADA2B transcriptional adaptor 2B 1.266
UBA2 ubiquitin-like modifier activating enzyme 2 1.262
MAPT microtubule-associated protein tau 1.262
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.262
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 1.262
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.259
BIRC2 baculoviral IAP repeat containing 2 1.257
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 1.255
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.252
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.251
ZNF569 zinc finger protein 569 1.251
NCOA3 nuclear receptor coactivator 3 1.25
ESR1 estrogen receptor 1 1.249
RNF4 ring finger protein 4 1.248
UBE2A ubiquitin-conjugating enzyme E2A 1.248
XBP1 X-box binding protein 1 1.247
UBE2R2 ubiquitin-conjugating enzyme E2R 2 1.246
ATXN7L3 ataxin 7-like 3 1.246
INS insulin 1.245
ZNF629 zinc finger protein 629 1.234
ZNF763 zinc finger protein 763 1.234
ZNF44 zinc finger protein 44 1.234
ZNF501 zinc finger protein 501 1.234
DERL1 derlin 1 1.233
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.232
ZNF436 zinc finger protein 436 1.232
RNF126 ring finger protein 126 1.23
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 1.225
CD8A CD8a molecule 1.221
KAT2A K(lysine) acetyltransferase 2A 1.219
FBF1 Fas (TNFRSF6) binding factor 1 1.216
RNF139 ring finger protein 139 1.213
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.212
YME1L1 YME1-like 1 ATPase 1.211
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 1.205
KAT2B K(lysine) acetyltransferase 2B 1.197
BRCA2 breast cancer 2, early onset 1.197
EGFR epidermal growth factor receptor 1.197
EIF3K eukaryotic translation initiation factor 3, subunit K 1.196
USP30 ubiquitin specific peptidase 30 1.195
USP36 ubiquitin specific peptidase 36 1.194
COPS8 COP9 signalosome subunit 8 1.193
COPS4 COP9 signalosome subunit 4 1.193
JUN jun proto-oncogene 1.189
CLSTN1 calsyntenin 1 1.189
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.189
CCDC74B coiled-coil domain containing 74B 1.184
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.181
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.179
PXDN peroxidasin 1.178
RTP5 receptor (chemosensory) transporter protein 5 (putative) 1.178
OTUD1 OTU deubiquitinase 1 1.177
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 1.172
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.171
PXDNL peroxidasin-like 1.169
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.169
TCHP trichoplein, keratin filament binding 1.168
UBL4A ubiquitin-like 4A 1.166
UBE2M ubiquitin-conjugating enzyme E2M 1.166
BAX BCL2-associated X protein 1.166
USP49 ubiquitin specific peptidase 49 1.165
OTUD7B OTU deubiquitinase 7B 1.163
ISG15 ISG15 ubiquitin-like modifier 1.162
USP25 ubiquitin specific peptidase 25 1.161
MINDY1 MINDY lysine 48 deubiquitinase 1 1.16
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 1.159
PGK1 phosphoglycerate kinase 1 1.159
DHFR dihydrofolate reductase 1.159
TCP1 t-complex 1 1.156
PTEN phosphatase and tensin homolog 1.155
ELOB elongin B 1.155
NFE2L3 nuclear factor, erythroid 2-like 3 1.153
OTULIN OTU deubiquitinase with linear linkage specificity 1.15
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.15
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.15
APP amyloid beta (A4) precursor protein 1.149
RNF114 ring finger protein 114 1.149
OTUD5 OTU deubiquitinase 5 1.149
CCNB1 cyclin B1 1.143
STIP1 stress-induced phosphoprotein 1 1.14
IL6 interleukin 6 1.138
USP26 ubiquitin specific peptidase 26 1.134
GABARAP GABA(A) receptor-associated protein 1.133
ATXN7L2 ataxin 7-like 2 1.133
TGFB1 transforming growth factor, beta 1 1.126
SUMO1 small ubiquitin-like modifier 1 1.123
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.122
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 1.119
USP46 ubiquitin specific peptidase 46 1.117
USP48 ubiquitin specific peptidase 48 1.112
TXN2 thioredoxin 2 1.111
ATM ATM serine/threonine kinase 1.111
SIRT1 sirtuin 1 1.107
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 1.106
HDAC9 histone deacetylase 9 1.104
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.101
PLAA phospholipase A2-activating protein 1.096
CD4 CD4 molecule 1.096
ERN1 endoplasmic reticulum to nucleus signaling 1 1.094
UNC50 unc-50 homolog (C. elegans) 1.091
PINK1 PTEN induced putative kinase 1 1.09
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.09
UBR5 ubiquitin protein ligase E3 component n-recognin 5 1.087
ANKZF1 ankyrin repeat and zinc finger domain containing 1 1.087
NFE2L2 nuclear factor, erythroid 2-like 2 1.087
MDM4 MDM4, p53 regulator 1.085
IL1B interleukin 1, beta 1.083
CDPF1 cysteine-rich, DPF motif domain containing 1 1.082
JOSD2 Josephin domain containing 2 1.082
CDK1 cyclin-dependent kinase 1 1.081
UBE2H ubiquitin-conjugating enzyme E2H 1.08
ATF6 activating transcription factor 6 1.078
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 1.077
TBP TATA box binding protein 1.077
CKS1B CDC28 protein kinase regulatory subunit 1B 1.074
CALML6 calmodulin-like 6 1.073
CALCOCO2 calcium binding and coiled-coil domain 2 1.072
CALML4 calmodulin-like 4 1.072
CHD7 chromodomain helicase DNA binding protein 7 1.072
CALML3 calmodulin-like 3 1.071
CALML5 calmodulin-like 5 1.071
UBR4 ubiquitin protein ligase E3 component n-recognin 4 1.069
TRIM21 tripartite motif containing 21 1.067
CYCS cytochrome c, somatic 1.066
CDK2 cyclin-dependent kinase 2 1.063
IGF1 insulin-like growth factor 1 (somatomedin C) 1.06
CD300C CD300c molecule 1.06
FOXM1 forkhead box M1 1.058
FAM120B family with sequence similarity 120B 1.057
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.057
ATXN7L1 ataxin 7-like 1 1.056
H4C7 H4 clustered histone 7 1.055
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.054
UIMC1 ubiquitin interaction motif containing 1 1.051
UBE3B ubiquitin protein ligase E3B 1.049
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.048
PHGDH phosphoglycerate dehydrogenase 1.045
PRSS3 protease, serine, 3 1.041
SP100 SP100 nuclear antigen 1.041
H2BC9 H2B clustered histone 9 1.04
FAF2 Fas associated factor family member 2 1.039
CREB1 cAMP responsive element binding protein 1 1.039
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.038
H4C15 H4 clustered histone 15 1.037
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 1.036
CAND1 cullin-associated and neddylation-dissociated 1 1.036
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.034
COPS7A COP9 signalosome subunit 7A 1.034
CCND1 cyclin D1 1.033
RAD51 RAD51 recombinase 1.032
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.03
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.029
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.028
USP17L2 ubiquitin specific peptidase 17-like family member 2 1.027
CUL2 cullin 2 1.026
ATG3 autophagy related 3 1.024
CHUK conserved helix-loop-helix ubiquitous kinase 1.024
DCAF11 DDB1 and CUL4 associated factor 11 1.023
SOD1 superoxide dismutase 1, soluble 1.021
YOD1 YOD1 deubiquitinase 1.02
USP18 ubiquitin specific peptidase 18 1.019
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.019
WWP2 WW domain containing E3 ubiquitin protein ligase 2 1.017
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 1.017
UBA3 ubiquitin-like modifier activating enzyme 3 1.016
AKIRIN2 akirin 2 1.015
GSK3B glycogen synthase kinase 3 beta 1.014
UBE2G1 ubiquitin-conjugating enzyme E2G 1 1.012
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.012
H2BC17 H2B clustered histone 17 1.012
UBE2I ubiquitin-conjugating enzyme E2I 1.01
DET1 de-etiolated homolog 1 (Arabidopsis) 1.01
PRSS58 protease, serine, 58 1.009
SGF29 SAGA complex associated factor 29 1.008
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 1.007
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.007
HDAC1 histone deacetylase 1 1.004
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.003
H2BC12 H2B clustered histone 12 1.003
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.002
DIABLO diablo, IAP-binding mitochondrial protein 1.002
E2F1 E2F transcription factor 1 1.001
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 1.0
BAG3 BCL2-associated athanogene 3 0.999
UBE2O ubiquitin-conjugating enzyme E2O 0.999
CUL5 cullin 5 0.999
MAPK3 mitogen-activated protein kinase 3 0.998
PDE4A phosphodiesterase 4A, cAMP-specific 0.998
EP300 E1A binding protein p300 0.996
H2BC1 H2B clustered histone 1 0.996
USP33 ubiquitin specific peptidase 33 0.993
ZC3H12A zinc finger CCCH-type containing 12A 0.992
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.99
H2BK1 H2B.K variant histone 1 0.988
OPTN optineurin 0.987
H2BW1 H2B.W histone 1 0.987
H2BW2 H2B.W histone 2 0.987
COPS2 COP9 signalosome subunit 2 0.986
H2BC12L H2B clustered histone 12 like 0.986
H2BC13 H2B clustered histone 13 0.985
ZNF346 zinc finger protein 346 0.984
ELOC elongin C 0.984
H2BC18 H2B clustered histone 18 0.984
RING1 ring finger protein 1 0.982
H2BC14 H2B clustered histone 14 0.982
H2BC26 H2B clustered histone 26 0.982
RNF2 ring finger protein 2 0.981
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.98
PARK7 parkinson protein 7 0.979
H2BC15 H2B clustered histone 15 0.979
USP6 ubiquitin specific peptidase 6 0.978
H2BC3 H2B clustered histone 3 0.977
FOXO3 forkhead box O3 0.976
EIF3E eukaryotic translation initiation factor 3, subunit E 0.976
H2BC11 H2B clustered histone 11 0.976
BCL2L1 BCL2-like 1 0.975
INO80 INO80 complex subunit 0.974
TXNL1 thioredoxin-like 1 0.971
NQO1 NAD(P)H dehydrogenase, quinone 1 0.97
PTTG2 pituitary tumor-transforming 2 0.969
H2BC4 H2B clustered histone 4 0.967
RAD18 RAD18 E3 ubiquitin protein ligase 0.966
YIPF1 Yip1 domain family, member 1 0.966
CDKN2A cyclin-dependent kinase inhibitor 2A 0.965
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.964
ISYNA1 inositol-3-phosphate synthase 1 0.964
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.964
H2BC5 H2B clustered histone 5 0.963
LTN1 listerin E3 ubiquitin protein ligase 1 0.961
EPS15 epidermal growth factor receptor pathway substrate 15 0.959
HSPE1 heat shock 10kDa protein 1 0.959
EIF4A1 eukaryotic translation initiation factor 4A1 0.958
SNRK SNF related kinase 0.957
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.953
HDAC3 histone deacetylase 3 0.951
FBXO7 F-box protein 7 0.95
CTSA cathepsin A 0.949
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.949
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.949
USP39 ubiquitin specific peptidase 39 0.948
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.947
RPS27A ribosomal protein S27a 0.947
CDK4 cyclin-dependent kinase 4 0.946
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 0.945
CHEK1 checkpoint kinase 1 0.942
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.94
DAXX death-domain associated protein 0.938
VWF von Willebrand factor 0.936
IKZF3 IKAROS family zinc finger 3 (Aiolos) 0.936
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.935
ANXA5 annexin A5 0.935
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.933
GGT5 gamma-glutamyltransferase 5 0.932
WDR20 WD repeat domain 20 0.931
ABRAXAS2 abraxas 2, BRISC complex subunit 0.93
CANX calnexin 0.929
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.927
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.926
SIRT2 sirtuin 2 0.924
EIF4A2 eukaryotic translation initiation factor 4A2 0.924
POU2F3 POU class 2 homeobox 3 0.924
EIF3H eukaryotic translation initiation factor 3, subunit H 0.923
GRM5 glutamate receptor, metabotropic 5 0.923
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.923
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 0.923
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.923
RIC3 RIC3 acetylcholine receptor chaperone 0.923
SEC63 SEC63 homolog (S. cerevisiae) 0.923
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 0.922
PTTG1 pituitary tumor-transforming 1 0.919
BRD4 bromodomain containing 4 0.915
MYH14 myosin, heavy chain 14, non-muscle 0.913
SUMO2 small ubiquitin-like modifier 2 0.911
HMOX1 heme oxygenase 1 0.909
MARCHF5 membrane associated ring-CH-type finger 5 0.909
IGF2R insulin-like growth factor 2 receptor 0.908
FOXO1 forkhead box O1 0.907
TRAF3 TNF receptor-associated factor 3 0.904
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.904
EGF epidermal growth factor 0.904
FUS FUS RNA binding protein 0.903
USP42 ubiquitin specific peptidase 42 0.903
DDB2 damage-specific DNA binding protein 2, 48kDa 0.902
RPLP2 ribosomal protein, large, P2 0.902
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.901
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.901
DPH1 diphthamide biosynthesis 1 0.899
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.899
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.899
NAE1 NEDD8 activating enzyme E1 subunit 1 0.899
DDIT3 DNA-damage-inducible transcript 3 0.898
TP53BP1 tumor protein p53 binding protein 1 0.898
NKRF NFKB repressing factor 0.898
USP32 ubiquitin specific peptidase 32 0.897
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.894
ERBB2 erb-b2 receptor tyrosine kinase 2 0.893
ANAPC10 anaphase promoting complex subunit 10 0.893
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.892
SHARPIN SHANK-associated RH domain interactor 0.891
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.891
CTSS cathepsin S 0.89
FBXO2 F-box protein 2 0.89
SMAD3 SMAD family member 3 0.888
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.888
TRIM54 tripartite motif containing 54 0.887
PPARG peroxisome proliferator-activated receptor gamma 0.887
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.882
HSPH1 heat shock 105kDa/110kDa protein 1 0.882
SMAD7 SMAD family member 7 0.881
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.881
EEF2 eukaryotic translation elongation factor 2 0.879
METAP1 methionyl aminopeptidase 1 0.879
DCAF15 DDB1 and CUL4 associated factor 15 0.876
RB1CC1 RB1-inducible coiled-coil 1 0.876
ATG13 autophagy related 13 0.875
PRRT1 proline-rich transmembrane protein 1 0.874
SUMO4 small ubiquitin-like modifier 4 0.872
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.869
PCNA proliferating cell nuclear antigen 0.868
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.868
EIF3C eukaryotic translation initiation factor 3, subunit C 0.866
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.866
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.866
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.865
BARD1 BRCA1 associated RING domain 1 0.863
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.862
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.862
SENP8 SUMO/sentrin specific peptidase family member 8 0.861
BDNF brain-derived neurotrophic factor 0.859
GET3 guided entry of tail-anchored proteins factor 3, ATPase 0.859
PKM pyruvate kinase, muscle 0.857
HAUS7 HAUS augmin-like complex, subunit 7 0.857
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.856
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.855
KCMF1 potassium channel modulatory factor 1 0.854
JOSD1 Josephin domain containing 1 0.852
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.851
ATXN1 ataxin 1 0.851
CDC20 cell division cycle 20 0.85
CD274 CD274 molecule 0.85
INSIG2 insulin induced gene 2 0.849
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.848
NFE2 nuclear factor, erythroid 2 0.848
FBXW8 F-box and WD repeat domain containing 8 0.848
USP29 ubiquitin specific peptidase 29 0.848
WDFY3 WD repeat and FYVE domain containing 3 0.847
CLCF1 cardiotrophin-like cytokine factor 1 0.847
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.847
TRIP12 thyroid hormone receptor interactor 12 0.846
IRS1 insulin receptor substrate 1 0.845
OTUD3 OTU deubiquitinase 3 0.845
TOM1 target of myb1 (chicken) 0.844
HDAC2 histone deacetylase 2 0.843
MIDN midnolin 0.841
SCGB1D4 secretoglobin, family 1D, member 4 0.838
OTUD6B OTU domain containing 6B 0.835
HSPB8 heat shock 22kDa protein 8 0.834
INSIG1 insulin induced gene 1 0.834
CDC37 cell division cycle 37 0.833
OR1J4 olfactory receptor, family 1, subfamily J, member 4 0.831
COMMD3-BMI1 COMMD3-BMI1 readthrough 0.826
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.826
USP17L25 ubiquitin specific peptidase 17-like family member 25 0.825
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.825
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.824
PEX6 peroxisomal biogenesis factor 6 0.823
CCNA2 cyclin A2 0.821
CCNA1 cyclin A1 0.821
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.821
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.819
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.819
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 0.819
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.818
H1-0 H1.0 linker histone 0.818
EIF3L eukaryotic translation initiation factor 3, subunit L 0.817
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.814
RANBP2 RAN binding protein 2 0.814
PSMC3IP PSMC3 interacting protein 0.814
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 0.813
INSR insulin receptor 0.812
PIH1D1 PIH1 domain containing 1 0.808
PHF1 PHD finger protein 1 0.807
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.806
JAK2 Janus kinase 2 0.805
NEMF nuclear export mediator factor 0.805
RNF41 ring finger protein 41, E3 ubiquitin protein ligase 0.804
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.804
TBL1X transducin (beta)-like 1X-linked 0.804
RPS5 ribosomal protein S5 0.804
DDA1 DET1 and DDB1 associated 1 0.803
HSPB1 heat shock 27kDa protein 1 0.803
URM1 ubiquitin related modifier 1 0.802
RO60 Ro60, Y RNA binding protein 0.801
UBAC2 UBA domain containing 2 0.8
FOS FBJ murine osteosarcoma viral oncogene homolog 0.8
LAP3 leucine aminopeptidase 3 0.8
HLA-F major histocompatibility complex, class I, F 0.799
TADA2A transcriptional adaptor 2A 0.798
RNF181 ring finger protein 181 0.798
RNF170 ring finger protein 170 0.793
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.792
IL10 interleukin 10 0.792
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.792
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.791
SKIC2 SKI2 subunit of superkiller complex 0.791
SMCO3 single-pass membrane protein with coiled-coil domains 3 0.788
PRNP prion protein 0.785
PRPF19 pre-mRNA processing factor 19 0.785
CHEK2 checkpoint kinase 2 0.785
ZNF879 zinc finger protein 879 0.784
PAX6 paired box 6 0.784
BIRC5 baculoviral IAP repeat containing 5 0.782
FBXO5 F-box protein 5 0.778
CDK5 cyclin-dependent kinase 5 0.778
ATF4 activating transcription factor 4 0.777
SIRT6 sirtuin 6 0.776
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.776
TLR4 toll-like receptor 4 0.776
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 0.774
UFM1 ubiquitin-fold modifier 1 0.774
SIAH1 siah E3 ubiquitin protein ligase 1 0.773
TPP2 tripeptidyl peptidase II 0.773
EEF1G eukaryotic translation elongation factor 1 gamma 0.772
TADA3 transcriptional adaptor 3 0.771
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.771
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.77
HSPA1B heat shock 70kDa protein 1B 0.768
UBE2L5 ubiquitin conjugating enzyme E2 L5 0.768
ANAPC5 anaphase promoting complex subunit 5 0.766
KLK11 kallikrein-related peptidase 11 0.766
ESS2 ess-2 splicing factor homolog 0.766
FKBP1A FK506 binding protein 1A, 12kDa 0.765
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.765
INO80E INO80 complex subunit E 0.765
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.765
MYB v-myb avian myeloblastosis viral oncogene homolog 0.765
TTR transthyretin 0.764
HSPB2 heat shock 27kDa protein 2 0.763
EIF3M eukaryotic translation initiation factor 3, subunit M 0.763
ANAPC11 anaphase promoting complex subunit 11 0.762
GATA5 GATA binding protein 5 0.762
PHF20 PHD finger protein 20 0.759
PLK1 polo-like kinase 1 0.759
KAT5 K(lysine) acetyltransferase 5 0.759
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.758
MFN1 mitofusin 1 0.758
HID1 HID1 domain containing 0.755
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.753
RPL27 ribosomal protein L27 0.753
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.752
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2 0.751
AURKB aurora kinase B 0.751
GCG glucagon 0.751
RHOD ras homolog family member D 0.749
RNF111 ring finger protein 111 0.747
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 0.747
CALR calreticulin 0.746
ATG14 autophagy related 14 0.746
MSTN myostatin 0.745
SERF1A small EDRK-rich factor 1A (telomeric) 0.744
FBXL3 F-box and leucine-rich repeat protein 3 0.74
CSNK1A1 casein kinase 1, alpha 1 0.739
PDE5A phosphodiesterase 5A, cGMP-specific 0.739
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.739
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.739
BABAM1 BRISC and BRCA1 A complex member 1 0.737
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.737
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.737
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.737
USP27X ubiquitin specific peptidase 27, X-linked 0.736
CREBBP CREB binding protein 0.736
HSPB3 heat shock 27kDa protein 3 0.735
HTRA2 HtrA serine peptidase 2 0.735
TRAT1 T cell receptor associated transmembrane adaptor 1 0.734
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.734
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.733
NGF nerve growth factor (beta polypeptide) 0.732
XPO1 exportin 1 0.732
CTSD cathepsin D 0.731
OR13J1 olfactory receptor, family 13, subfamily J, member 1 0.731
ARRB2 arrestin, beta 2 0.731
MCM3AP minichromosome maintenance complex component 3 associated protein 0.731
PFDN2 prefoldin subunit 2 0.729
CDKN3 cyclin-dependent kinase inhibitor 3 0.728
PEPD peptidase D 0.728
PPARA peroxisome proliferator-activated receptor alpha 0.727
IL2 interleukin 2 0.727
APOE apolipoprotein E 0.726
HDAC8 histone deacetylase 8 0.725
TXNIP thioredoxin interacting protein 0.723
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.722
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 0.722
UVRAG UV radiation resistance associated 0.72
RNF123 ring finger protein 123 0.719
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.719
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.719
IL1A interleukin 1, alpha 0.718
TXNRD1 thioredoxin reductase 1 0.718
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.716
DVL1 dishevelled segment polarity protein 1 0.715
TAC4 tachykinin 4 (hemokinin) 0.714
ATG101 autophagy related 101 0.714
PNO1 partner of NOB1 homolog (S. cerevisiae) 0.713
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.713
SMAD2 SMAD family member 2 0.712
CDC23 cell division cycle 23 0.712
PDIA6 protein disulfide isomerase family A, member 6 0.711
WEE1 WEE1 G2 checkpoint kinase 0.711
PTBP2 polypyrimidine tract binding protein 2 0.71
NSFL1C NSFL1 (p97) cofactor (p47) 0.71
RIPK2 receptor-interacting serine-threonine kinase 2 0.709
METAP2 methionyl aminopeptidase 2 0.709
ANKMY2 ankyrin repeat and MYND domain containing 2 0.708
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.708
SMAD4 SMAD family member 4 0.707
BAG2 BCL2-associated athanogene 2 0.706
SOX2 SRY (sex determining region Y)-box 2 0.706
TFEB transcription factor EB 0.706
ZNF7 zinc finger protein 7 0.705
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 0.704
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 0.704
STAT1 signal transducer and activator of transcription 1, 91kDa 0.702
GRM2 glutamate receptor, metabotropic 2 0.701
ZNF236 zinc finger protein 236 0.701
SNRPA small nuclear ribonucleoprotein polypeptide A 0.701
LOC112694756 uncharaterized LOC112694756 0.701
TRIM32 tripartite motif containing 32 0.7
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.699
H2AZ1 H2A.Z variant histone 1 0.698
CDK6 cyclin-dependent kinase 6 0.696
SOCS1 suppressor of cytokine signaling 1 0.696
UBP1 upstream binding protein 1 (LBP-1a) 0.695
ROPN1L rhophilin associated tail protein 1-like 0.695
RTL10 retrotransposon Gag like 10 0.693
IPO9 importin 9 0.691
UBE2T ubiquitin-conjugating enzyme E2T 0.691
TRIM11 tripartite motif containing 11 0.69
CCL2 chemokine (C-C motif) ligand 2 0.688
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.685
RUVBL1 RuvB-like AAA ATPase 1 0.684
CNOT1 CCR4-NOT transcription complex, subunit 1 0.684
ERCC1 excision repair cross-complementation group 1 0.683
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 0.683
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.683
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.682
ENO1 enolase 1, (alpha) 0.681
USP50 ubiquitin specific peptidase 50 0.681
CDC6 cell division cycle 6 0.681
DCAF16 DDB1 and CUL4 associated factor 16 0.68
GLRX2 glutaredoxin 2 0.679
TBK1 TANK-binding kinase 1 0.679
GRM4 glutamate receptor, metabotropic 4 0.677
TRIM17 tripartite motif containing 17 0.677
CNOT2 CCR4-NOT transcription complex, subunit 2 0.676
ERLEC1 endoplasmic reticulum lectin 1 0.676
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.676
CDC25C cell division cycle 25C 0.675
IFNA1 interferon, alpha 1 0.675
ZPR1 ZPR1 zinc finger 0.675
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.674
DEFB135 defensin, beta 135 0.673
TOLLIP toll interacting protein 0.673
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.672
TBL3 transducin (beta)-like 3 0.672
CTSB cathepsin B 0.67
COPS9 COP9 signalosome subunit 9 0.668
RCC1 regulator of chromosome condensation 1 0.667
SESN2 sestrin 2 0.667
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.666
AGXT alanine-glyoxylate aminotransferase 0.665
TYMS thymidylate synthetase 0.665
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.665
BTK Bruton agammaglobulinemia tyrosine kinase 0.664
GLB1 galactosidase, beta 1 0.663
CFLAR CASP8 and FADD-like apoptosis regulator 0.663
CXCL8 chemokine (C-X-C motif) ligand 8 0.663
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.663
MFN2 mitofusin 2 0.662
RNF216 ring finger protein 216 0.662
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.662
MOGS mannosyl-oligosaccharide glucosidase 0.661
UBE2Z ubiquitin-conjugating enzyme E2Z 0.66
UBAP2L ubiquitin associated protein 2-like 0.659
SRI sorcin 0.659
PRKG1 protein kinase, cGMP-dependent, type I 0.658
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.657
FANCD2 Fanconi anemia, complementation group D2 0.657
CKB creatine kinase, brain 0.657
MAP1B microtubule-associated protein 1B 0.656
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.656
RNF7 ring finger protein 7 0.656
PRR33 proline rich 33 0.655
MAPK7 mitogen-activated protein kinase 7 0.655
GTF2B general transcription factor IIB 0.655
TRIP13 thyroid hormone receptor interactor 13 0.654
ADCY10 adenylate cyclase 10 (soluble) 0.653
ARRB1 arrestin, beta 1 0.653
RUVBL2 RuvB-like AAA ATPase 2 0.651
STAT5A signal transducer and activator of transcription 5A 0.65
KRT38 keratin 38, type I 0.65
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 0.65
JAK1 Janus kinase 1 0.649
GLP1R glucagon-like peptide 1 receptor 0.649
EIF4E eukaryotic translation initiation factor 4E 0.649
OGA O-GlcNAcase 0.647
BIRC3 baculoviral IAP repeat containing 3 0.646
SP4 Sp4 transcription factor 0.645
STK11 serine/threonine kinase 11 0.644
IRF3 interferon regulatory factor 3 0.642
CNOT9 CCR4-NOT transcription complex subunit 9 0.642
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.641
NCOR1 nuclear receptor corepressor 1 0.64
RPN1 ribophorin I 0.639
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.637
RARA retinoic acid receptor, alpha 0.636
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.636
FBXO4 F-box protein 4 0.635
CRABP2 cellular retinoic acid binding protein 2 0.633
TSC2 tuberous sclerosis 2 0.633
FBXO40 F-box protein 40 0.631
CELF3 CUGBP, Elav-like family member 3 0.631
IDE insulin-degrading enzyme 0.631
SFRP4 secreted frizzled-related protein 4 0.63
SPINT4 serine peptidase inhibitor, Kunitz type 4 0.63
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.63
JAG2 jagged 2 0.63
TH tyrosine hydroxylase 0.629
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.628
FMR1 fragile X mental retardation 1 0.628
C6ORF89 chromosome 6 open reading frame 89 0.628
P4HB prolyl 4-hydroxylase, beta polypeptide 0.627
DLAT dihydrolipoamide S-acetyltransferase 0.627
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.627
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.626
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.626
MKRN2 makorin ring finger protein 2 0.625
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 0.625
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 0.625
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.624
SNAI1 snail family zinc finger 1 0.624
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.624
HPGDS hematopoietic prostaglandin D synthase 0.623
GMPS guanine monphosphate synthase 0.622
ZNF621 zinc finger protein 621 0.621
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.621
ASB15 ankyrin repeat and SOCS box containing 15 0.62
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.619
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.619
RAB1A RAB1A, member RAS oncogene family 0.617
CDC16 cell division cycle 16 0.617
TRIM50 tripartite motif containing 50 0.616
ADORA1 adenosine A1 receptor 0.616
PUS1 pseudouridylate synthase 1 0.616
EIF3B eukaryotic translation initiation factor 3, subunit B 0.616
GJD3 gap junction protein, delta 3, 31.9kDa 0.616
TGFBR1 transforming growth factor, beta receptor 1 0.615
CAMLG calcium modulating ligand 0.613
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.613
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.613
KLHL12 kelch-like family member 12 0.612
HBS1L HBS1-like translational GTPase 0.612
PDIA3 protein disulfide isomerase family A, member 3 0.612
USP35 ubiquitin specific peptidase 35 0.611
RABIF RAB interacting factor 0.611
FBXO38 F-box protein 38 0.611
PSEN1 presenilin 1 0.611
TRIM25 tripartite motif containing 25 0.61
NPTX1 neuronal pentraxin I 0.61
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.61
TALDO1 transaldolase 1 0.61
HCFC1 host cell factor C1 0.61
GLRX glutaredoxin (thioltransferase) 0.609
ATF3 activating transcription factor 3 0.608
IGF1R insulin-like growth factor 1 receptor 0.608
TRIM58 tripartite motif containing 58 0.606
ACO1 aconitase 1, soluble 0.606
ATG10 autophagy related 10 0.606
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.605
FKBP5 FK506 binding protein 5 0.605
TRIM23 tripartite motif containing 23 0.604
GRM1 glutamate receptor, metabotropic 1 0.603
DNM1L dynamin 1-like 0.603
CKM creatine kinase, muscle 0.603
HNF1A HNF1 homeobox A 0.603
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.602
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.601
PRDX1 peroxiredoxin 1 0.601
BIRC7 baculoviral IAP repeat containing 7 0.601
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 0.601
GRM3 glutamate receptor, metabotropic 3 0.6
RPS6 ribosomal protein S6 0.6
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 0.599
UBASH3B ubiquitin associated and SH3 domain containing B 0.599
UBE2F ubiquitin-conjugating enzyme E2F (putative) 0.599
AMBRA1 autophagy/beclin-1 regulator 1 0.599
MEIS2 Meis homeobox 2 0.597
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.597
DEPTOR DEP domain containing MTOR-interacting protein 0.597
RNF11 ring finger protein 11 0.595
GRID1 glutamate receptor, ionotropic, delta 1 0.595
IFNB1 interferon, beta 1, fibroblast 0.594
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.594
TERT telomerase reverse transcriptase 0.594
PFDN5 prefoldin subunit 5 0.593
CRHR1 corticotropin releasing hormone receptor 1 0.592
ERBB3 erb-b2 receptor tyrosine kinase 3 0.592
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.591
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.591
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 0.59
APAF1 apoptotic peptidase activating factor 1 0.589
FBXW11 F-box and WD repeat domain containing 11 0.589
VCAM1 vascular cell adhesion molecule 1 0.588
SEC62 SEC62 homolog (S. cerevisiae) 0.588
RPL7 ribosomal protein L7 0.586
OR4C13 olfactory receptor, family 4, subfamily C, member 13 0.586
CUL7 cullin 7 0.586
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.585
CKMT1B creatine kinase, mitochondrial 1B 0.585
CLSPN claspin 0.585
TRAP1 TNF receptor-associated protein 1 0.585
BCLAF1 BCL2-associated transcription factor 1 0.584
RPAP3 RNA polymerase II associated protein 3 0.584
NOTCH1 notch 1 0.582
CXCR4 chemokine (C-X-C motif) receptor 4 0.582
ACE angiotensin I converting enzyme 0.582
TRRAP transformation/transcription domain-associated protein 0.582
VDAC1 voltage-dependent anion channel 1 0.582
H2AX H2A.X variant histone 0.582
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 0.581
CAPN2 calpain 2, (m/II) large subunit 0.581
SATL1 spermidine/spermine N1-acetyl transferase-like 1 0.58
FBXO3 F-box protein 3 0.58
GRM7 glutamate receptor, metabotropic 7 0.579
SP3 Sp3 transcription factor 0.579
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.578
MORF4L1 mortality factor 4 like 1 0.578
DIAPH1 diaphanous-related formin 1 0.577
NSD2 nuclear receptor binding SET domain protein 2 0.577
ADA2 adenosine deaminase 2 0.577
CDT1 chromatin licensing and DNA replication factor 1 0.576
CASR calcium-sensing receptor 0.576
SIAH2 siah E3 ubiquitin protein ligase 2 0.575
RIC1 RAB6A GEF complex partner 1 0.575
IL17F interleukin 17F 0.574
CTAG2 cancer/testis antigen 2 0.574
ACVR1 activin A receptor, type I 0.573
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.573
KDM4A lysine (K)-specific demethylase 4A 0.573
NPEPPS aminopeptidase puromycin sensitive 0.572
NANOS3 nanos homolog 3 (Drosophila) 0.572
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.572
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8 0.571
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.571
ADRB2 adrenoceptor beta 2, surface 0.571
BLM Bloom syndrome, RecQ helicase-like 0.571
MAP1S microtubule-associated protein 1S 0.57
ZNF844 zinc finger protein 844 0.57
EGR1 early growth response 1 0.57
RIGI RNA sensor RIG-I 0.57