Pseudotumor Cerebri Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_11459)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D011559
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Genes

180 genes/proteins associated with the disease Pseudotumor Cerebri from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNF tumor necrosis factor 1.98096
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.9604
IL1B interleukin 1, beta 1.85327
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.83735
VEGFA vascular endothelial growth factor A 1.82726
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.77218
BAX BCL2-associated X protein 1.69805
IL6 interleukin 6 1.67569
BCL2 B-cell CLL/lymphoma 2 1.65045
POMC proopiomelanocortin 1.63631
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.55772
TAGLN transgelin 1.5462
CAT catalase 1.53844
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.50852
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.50599
CXCL8 chemokine (C-X-C motif) ligand 8 1.50298
KRT8 keratin 8, type II 1.48941
JUN jun proto-oncogene 1.47966
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.47787
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.46883
TP53 tumor protein p53 1.45194
IL2 interleukin 2 1.44599
CKB creatine kinase, brain 1.44436
IFNG interferon, gamma 1.44139
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.42642
CCL2 chemokine (C-C motif) ligand 2 1.41229
IL4 interleukin 4 1.41119
TGFB1 transforming growth factor, beta 1 1.40925
S100A9 S100 calcium binding protein A9 1.40092
G6PD glucose-6-phosphate dehydrogenase 1.38696
GLUL glutamate-ammonia ligase 1.38412
CA2 carbonic anhydrase II 1.38213
NPY neuropeptide Y 1.35127
RXRG retinoid X receptor, gamma 1.34782
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.34782
PLG plasminogen 1.34024
MMP13 matrix metallopeptidase 13 1.3385
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 1.33523
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.32015
AR androgen receptor 1.30026
NCOA1 nuclear receptor coactivator 1 1.30026
MMP2 matrix metallopeptidase 2 1.29812
IGFBP3 insulin-like growth factor binding protein 3 1.28827
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.28672
RXRA retinoid X receptor, alpha 1.28672
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.28088
SPP1 secreted phosphoprotein 1 1.27936
BGLAP bone gamma-carboxyglutamate (gla) protein 1.27689
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.26205
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.25929
PLAT plasminogen activator, tissue 1.25838
PLTP phospholipid transfer protein 1.25745
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.25245
COL1A1 collagen, type I, alpha 1 1.24812
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.2456
S100A8 S100 calcium binding protein A8 1.24087
THBS1 thrombospondin 1 1.23552
RHOA ras homolog family member A 1.23552
GSTM1 glutathione S-transferase mu 1 1.2352
APP amyloid beta (A4) precursor protein 1.22948
DNASE1 deoxyribonuclease I 1.22632
FASN fatty acid synthase 1.22501
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.22404
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.21984
FAS Fas cell surface death receptor 1.21887
PIR pirin (iron-binding nuclear protein) 1.21304
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.21173
FOS FBJ murine osteosarcoma viral oncogene homolog 1.21076
MMP9 matrix metallopeptidase 9 1.20751
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.20526
ALB albumin 1.2046
GRB7 growth factor receptor-bound protein 7 1.20427
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.20229
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.20163
MPO myeloperoxidase 1.20163
IGF1 insulin-like growth factor 1 (somatomedin C) 1.19999
ANXA4 annexin A4 1.19966
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.19966
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.19737
PPARG peroxisome proliferator-activated receptor gamma 1.19509
IL12B interleukin 12B 1.19146
FN1 fibronectin 1 1.19047
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.18816
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.18226
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.17959
SOCS2 suppressor of cytokine signaling 2 1.17959
EGFR epidermal growth factor receptor 1.17926
MMP3 matrix metallopeptidase 3 1.17464
LAMA2 laminin, alpha 2 1.17067
KCTD12 potassium channel tetramerization domain containing 12 1.17067
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.16833
ETFDH electron-transferring-flavoprotein dehydrogenase 1.1617
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.15661
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.15627
TGFB3 transforming growth factor, beta 3 1.15425
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 1.15425
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.15391
VGF VGF nerve growth factor inducible 1.15357
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.14989
TIMP1 TIMP metallopeptidase inhibitor 1 1.14954
PARP1 poly (ADP-ribose) polymerase 1 1.14473
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.14404
NOX4 NADPH oxidase 4 1.13724
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.13313
NOS2 nitric oxide synthase 2, inducible 1.13245
ESR1 estrogen receptor 1 1.13211
IL10RA interleukin 10 receptor, alpha 1.12973
SRGN serglycin 1.12599
RHOB ras homolog family member B 1.12495
FMO1 flavin containing monooxygenase 1 1.12495
GSTP1 glutathione S-transferase pi 1 1.12288
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 1.12254
IL5 interleukin 5 1.11911
PGD phosphogluconate dehydrogenase 1.11911
GDF15 growth differentiation factor 15 1.11877
CECR1 cat eye syndrome chromosome region, candidate 1 1.11639
BMP4 bone morphogenetic protein 4 1.11536
APOE apolipoprotein E 1.11536
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.11325
GJA1 gap junction protein, alpha 1, 43kDa 1.1129
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.1129
HBEGF heparin-binding EGF-like growth factor 1.09857
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.09822
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.09681
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.09646
C10ORF10 chromosome 10 open reading frame 10 1.09506
FBLN1 fibulin 1 1.09506
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.09506
DUSP1 dual specificity phosphatase 1 1.09436
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.09154
ELMOD3 ELMO/CED-12 domain containing 3 1.09011
CRABP2 cellular retinoic acid binding protein 2 1.08868
RARG retinoic acid receptor, gamma 1.08584
RARA retinoic acid receptor, alpha 1.08266
KRT17 keratin 17, type I 1.07625
GTPBP1 GTP binding protein 1 1.07625
TGM2 transglutaminase 2 1.07447
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.07128
HMHA1 histocompatibility (minor) HA-1 1.06952
CCL3 chemokine (C-C motif) ligand 3 1.06808
COL6A3 collagen, type VI, alpha 3 1.06771
LYN LYN proto-oncogene, Src family tyrosine kinase 1.06734
PRL prolactin 1.06588
SC5D sterol-C5-desaturase 1.06479
SPRR1B small proline-rich protein 1B 1.06406
PPARA peroxisome proliferator-activated receptor alpha 1.0637
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.06297
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.06297
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.06261
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 1.05936
NDRG2 NDRG family member 2 1.05312
NES nestin 1.04757
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.04757
CRYAB crystallin, alpha B 1.04684
PER1 period circadian clock 1 1.04501
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.04427
GSR glutathione reductase 1.03752
CREB1 cAMP responsive element binding protein 1 1.03641
GSTM3 glutathione S-transferase mu 3 (brain) 1.03641
CCND1 cyclin D1 1.03567
EPX eosinophil peroxidase 1.03419
HMOX1 heme oxygenase 1 1.03419
NKX2-1 NK2 homeobox 1 1.03382
MEIS1 Meis homeobox 1 1.03382
RAD17 RAD17 homolog (S. pombe) 1.03271
SDC4 syndecan 4 1.03235
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.03197
SOD2 superoxide dismutase 2, mitochondrial 1.03084
MAP2 microtubule-associated protein 2 1.02708
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 1.02671
RGS8 regulator of G-protein signaling 8 1.02262
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 1.02225
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.02188
CAPN2 calpain 2, (m/II) large subunit 1.02003
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.01928
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.01928
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.01739
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.01549
CXCL2 chemokine (C-X-C motif) ligand 2 1.01474
MAPK4 mitogen-activated protein kinase 4 1.01174