Psoriasis Vulgaris Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group immune (Genetic Association Database)
External Link https://www.disgenet.org/browser/0/1/0/C0263361
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Genes

233 genes associated with the disease Psoriasis Vulgaris in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
AFF3 AF4/FMR2 family, member 3
AHR aryl hydrocarbon receptor
AKR1C3 aldo-keto reductase family 1, member C3
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
APOE apolipoprotein E
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BTLA B and T lymphocyte associated
BTNL2 butyrophilin-like 2
C1ORF228 chromosome 1 open reading frame 228
CALCA calcitonin-related polypeptide alpha
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMP cathelicidin antimicrobial peptide
CARD10 caspase recruitment domain family, member 10
CARD11 caspase recruitment domain family, member 11
CARD14 caspase recruitment domain family, member 14
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CCL5 chemokine (C-C motif) ligand 5
CCN1 cellular communication network factor 1
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CD19 CD19 molecule
CD1C CD1c molecule
CD207 CD207 molecule, langerin
CD34 CD34 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDSN corneodesmosin
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLEC4C C-type lectin domain family 4, member C
COG6 component of oligomeric golgi complex 6
CRNN cornulin
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
DEFB1 defensin, beta 1
DEFB4A defensin, beta 4A
DEFB4B defensin, beta 4B
DST dystonin
EBNA1BP2 EBNA1 binding protein 2
EDN1 endothelin 1
EGF epidermal growth factor
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ELOVL6 ELOVL fatty acid elongase 6
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
F9 coagulation factor IX
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FGFR3 fibroblast growth factor receptor 3
FLG filaggrin
FLNB filamin B, beta
FOXA2 forkhead box A2
FOXP3 forkhead box P3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GEM GTP binding protein overexpressed in skeletal muscle
GJB2 gap junction protein, beta 2, 26kDa
GRN granulin
GSS glutathione synthetase
GSTK1 glutathione S-transferase kappa 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HMOX1 heme oxygenase 1
HPGDS hematopoietic prostaglandin D synthase
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFNG interferon, gamma
IFNLR1 interferon, lambda receptor 1
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL36RN interleukin 36 receptor antagonist
IL37 interleukin 37
IL3RA interleukin 3 receptor, alpha (low affinity)
IL6 interleukin 6
IL7 interleukin 7
IL9 interleukin 9
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
IVL involucrin
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DL5B killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLK3 kallikrein-related peptidase 3
KRT17 keratin 17, type I
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LCE3D late cornified envelope 3D
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LTA lymphotoxin alpha
LYNX1 Ly6/neurotoxin 1
MAPK1 mitogen-activated protein kinase 1
MGST2 microsomal glutathione S-transferase 2
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MME membrane metallo-endopeptidase
MMEL1 membrane metallo-endopeptidase-like 1
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC22 mucin 22
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH4 notch 4
NPEPPS aminopeptidase puromycin sensitive
NR1I2 nuclear receptor subfamily 1, group I, member 2
NXF1 nuclear RNA export factor 1
PIPOX pipecolic acid oxidase
PLAG1 pleiomorphic adenoma gene 1
PLCL2 phospholipase C-like 2
PLXNB1 plexin B1
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
PPARG peroxisome proliferator-activated receptor gamma
PRL prolactin
PRO2268 uncharacterized protein PRO2268
PROS1 protein S (alpha)
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
PSIP1 PC4 and SFRS1 interacting protein 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSORS1C2 psoriasis susceptibility 1 candidate 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTTG1 pituitary tumor-transforming 1
QTRT1 queuine tRNA-ribosyltransferase 1
RABEPK Rab9 effector protein with kelch motifs
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM45 RNA binding motif protein 45
RDX radixin
REG1A regenerating islet-derived 1 alpha
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RMI2 RecQ mediated genome instability 2
RNF114 ring finger protein 114
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RORC RAR-related orphan receptor C
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPSA ribosomal protein SA
RUNX3 runt-related transcription factor 3
S100A7 S100 calcium binding protein A7
SEC14L2 SEC14-like 2 (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC12A8 solute carrier family 12, member 8
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLURP1 secreted LY6/PLAUR domain containing 1
SPARCL1 SPARC-like 1 (hevin)
SRSF1 serine/arginine-rich splicing factor 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STX1B syntaxin 1B
SUMO4 small ubiquitin-like modifier 4
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R13 taste receptor, type 2, member 13
TCF19 transcription factor 19
TCHHL1 trichohyalin-like 1
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMPRSS11D transmembrane protease, serine 11D
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TP63 tumor protein p63
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIB3 tribbles pseudokinase 3
TSHZ1 teashirt zinc finger homeobox 1
TYK2 tyrosine kinase 2
UBE2L3 ubiquitin-conjugating enzyme E2L 3
USO1 USO1 vesicle transport factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF816 zinc finger protein 816