Psychotic Disorders Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D011618
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Genes

163 genes/proteins associated with the disease Psychotic Disorders from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
DRD5 dopamine receptor D5 2.88009
SNAP25 synaptosomal-associated protein, 25kDa 2.88009
SELENBP1 selenium binding protein 1 2.88009
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.88009
PVALB parvalbumin 2.88009
BDNF brain-derived neurotrophic factor 2.88009
CPLX1 complexin 1 2.88009
AVP arginine vasopressin 2.88009
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.88009
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.88009
CPLX2 complexin 2 2.88009
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 2.88009
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.88009
DRD2 dopamine receptor D2 2.48214
PRL prolactin 2.45202
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.36145
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.26063
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.22823
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.189
DRD1 dopamine receptor D1 2.15965
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.12979
FOS FBJ murine osteosarcoma viral oncogene homolog 2.08573
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 2.03807
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.01691
CAT catalase 1.96979
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.91485
EGR1 early growth response 1 1.8836
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.83859
DRD3 dopamine receptor D3 1.83148
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.8306
NPY neuropeptide Y 1.80322
NUPR1 nuclear protein, transcriptional regulator, 1 1.78911
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.76771
PENK proenkephalin 1.76309
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.7546
TAGLN transgelin 1.7226
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.69534
MAOB monoamine oxidase B 1.67868
CRH corticotropin releasing hormone 1.65402
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.64887
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.64438
SOD1 superoxide dismutase 1, soluble 1.63921
MAPK1 mitogen-activated protein kinase 1 1.62036
IL6 interleukin 6 1.61529
INHBE inhibin, beta E 1.61154
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.59404
BAX BCL2-associated X protein 1.58561
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.57665
DUSP1 dual specificity phosphatase 1 1.56971
POMC proopiomelanocortin 1.5673
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.56484
TH tyrosine hydroxylase 1.55896
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.53868
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.53357
ARC activity-regulated cytoskeleton-associated protein 1.53135
TNF tumor necrosis factor 1.52489
JUNB jun B proto-oncogene 1.52111
C10ORF10 chromosome 10 open reading frame 10 1.51734
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.51506
BCL2 B-cell CLL/lymphoma 2 1.5143
MAPK3 mitogen-activated protein kinase 3 1.51405
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.50198
CREB1 cAMP responsive element binding protein 1 1.49045
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.46568
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.44899
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.44626
JUN jun proto-oncogene 1.44273
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.43809
CNR1 cannabinoid receptor 1 (brain) 1.437
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.42562
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.41451
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.40429
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.39813
PDYN prodynorphin 1.38835
GFAP glial fibrillary acidic protein 1.38298
TAC1 tachykinin, precursor 1 1.37705
FABP1 fatty acid binding protein 1, liver 1.36848
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.3639
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.34401
MAOA monoamine oxidase A 1.33966
PER1 period circadian clock 1 1.33022
GSK3A glycogen synthase kinase 3 alpha 1.32637
GSTP1 glutathione S-transferase pi 1 1.32518
CDK5 cyclin-dependent kinase 5 1.31626
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.30881
FNDC4 fibronectin type III domain containing 4 1.2941
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.29164
FOSL2 FOS-like antigen 2 1.28858
FAS Fas cell surface death receptor 1.28549
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.28241
DRD4 dopamine receptor D4 1.28241
RGS2 regulator of G-protein signaling 2 1.28119
GRIK2 glutamate receptor, ionotropic, kainate 2 1.27997
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.26483
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.26021
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.25214
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.24843
RELN reelin 1.23993
HOMER1 homer scaffolding protein 1 1.23993
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.23962
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.23552
SREBF2 sterol regulatory element binding transcription factor 2 1.23201
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.20946
MBP myelin basic protein 1.20913
SREBF1 sterol regulatory element binding transcription factor 1 1.20064
SOD2 superoxide dismutase 2, mitochondrial 1.19312
RGS4 regulator of G-protein signaling 4 1.19146
GSK3B glycogen synthase kinase 3 beta 1.18849
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.18718
HPN hepsin 1.18126
GAL galanin/GMAP prepropeptide 1.18093
MAP2 microtubule-associated protein 2 1.17761
PRKCZ protein kinase C, zeta 1.17761
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.17761
INHA inhibin, alpha 1.17629
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.16467
GDNF glial cell derived neurotrophic factor 1.15831
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.15797
PHYH phytanoyl-CoA 2-hydroxylase 1.15729
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.15729
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.15492
IL10 interleukin 10 1.15223
GRM1 glutamate receptor, metabotropic 1 1.14816
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.14473
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.14166
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.13862
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.13245
TPI1 triosephosphate isomerase 1 1.13041
NGF nerve growth factor (beta polypeptide) 1.12805
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.12634
SCG2 secretogranin II 1.12599
GRM2 glutamate receptor, metabotropic 2 1.12599
VEGFA vascular endothelial growth factor A 1.12288
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.11809
OPRM1 opioid receptor, mu 1 1.11639
MAPK8 mitogen-activated protein kinase 8 1.11501
INS insulin 1.10838
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.10631
PARP1 poly (ADP-ribose) polymerase 1 1.10211
NOS2 nitric oxide synthase 2, inducible 1.08868
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.08266
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.08231
CHGA chromogranin A 1.07696
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.06881
EGR2 early growth response 2 1.06297
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.0608
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.05648
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.04501
NTS neurotensin 1.04126
COMT catechol-O-methyltransferase 1.03122
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.03046
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.03009
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.02971
ALDOC aldolase C, fructose-bisphosphate 1.02821
LDLR low density lipoprotein receptor 1.02783
CCND1 cyclin D1 1.02708
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.02522
DUSP6 dual specificity phosphatase 6 1.01814
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.01587
CRP C-reactive protein, pentraxin-related 1.01399
MAP2K2 mitogen-activated protein kinase kinase 2 1.01361
HPCA hippocalcin 1.01361
MAP2K1 mitogen-activated protein kinase kinase 1 1.01249